Effect of Dietary Inclusion of Lemon Balm (&lt;i&gt;Melissa Officinalis &lt;/i&gt;L.) Extract on Performance, Gut Microflora, Blood Parameters, Immunity and Carcass Traits of Broilers

Poorghasemi, Mohammadreza; Seidavi, Alireza; Mohammadi, M; Simões, João; Laudadio, Vito; Tufarelli, Vincenzo

doi:10.2141/jpsa.0170001

Cited by 6 publications

(9 citation statements)

References 22 publications

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“…Interestingly, the performance of these chickens was improved during the grower phase with also a trend for a lower occurrence of muscle defects. These effects of MEL extract supplementation on chicken performance have been described previously (20,21) and are strengthened by our study. The beneficial antioxidative activity of MEL was also reported on the quality of meat by limited lipid oxidation (20).…”

Section: Discussionsupporting

confidence: 89%

“…Nevertheless, few studies have demonstrated and documented the capacity of MEL extract to improve the defense system of chickens and its impact on their health, welfare and performance (20,21). The different steps reported in this study range from the quality of MEL extract, its possible cytotoxicity on chicken cell lines and its potential to stimulate immune functions in vitro, the capacity to reveal its antioxidative and anti-inflammatory properties in an original ex vivo model of inflammation to the assessment of its effects on welfare, health and performance indicators in chickens reared in suboptimal conditions.…”

Section: Discussionmentioning

confidence: 99%

“…The pellet preparation was performed at 70 • C. The composition of the basal feed for each breeding period, is described in Tables 1, 3. Based on references (20,21), MEL extract was supplemented at 1% (10 g/kg) into the mash which was then granulated. To evaluate the impact of the granulation process, the supplement rate of RA and the recovery rate in mash and pellets were measured using HPLC-DAD and HPLC-FLUO methods.…”

Section: Feed Preparationmentioning

confidence: 99%

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Methodologies to Assess the Bioactivity of an Herbal Extract on Immunity, Health, Welfare and Production Performance in the Chicken: The Case of Melissa officinalis L. Extract

et al. 2021

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The potential of herbal extracts containing bioactive compounds to strengthen immunity could contribute to reducing antimicrobial use in poultry. This study aimed at developing a reliable and robust methodological pipeline to assess the ability of herbal extracts to strengthen chicken innate defenses, especially concerning inflammation and oxidative stress. This methodology was applied to Melissa officinalis L. (MEL) extract, recognized for its biological activities including antioxidant and anti-inflammatory properties. Different methods were used to (1). guarantee the quality of MEL extract and its capacity to stimulate the innate immune system; (2). evaluate the relevance of an ex vivo model to mimic inflammatory and oxidative stress challenges to replace LPS injection in chickens; (3). analyse the effects of feed supplemented with MEL extract on inflammation and oxidative stress induced ex vivo; (4). assess the effects of MEL extract on the redox balance, health, welfare and performance in broilers exposed to suboptimal starting conditions through a large-scale approach. The quality of MEL extract preparations, through phytochemical quantification of rosmarinic acid (RA), revealed varying concentrations of RA in the different MEL extracts. RA concentrations remained stable for at least 9 months and in feed three months after incorporating MEL extract. When incubated with chicken cell lines MEL extract showed potential metabolic activation and ability to stimulate immune functions but induced cytotoxicity at high concentrations. The original ex vivo model of inflammation developed on chicken blood cells enabled inflammation and oxidative stress biomarkers to be expressed and revealed antioxidative and anti-inflammatory properties of blood cells from chickens fed MEL extract. The experimental model of chicken suboptimal starting conditions validated beneficial effects of MEL extract on the redox balance and also evidenced improved performance during the growth phase, a tendency for fewer muscle defects but a higher severity of pododermatitis lesions without affecting other welfare indicators. This study grouped methods and tools that could be combined according to the plant extract, the needs of professionals working in poultry production systems and staff responsible for animal health, welfare and feeding.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Section: Feed Preparationmentioning

confidence: 99%

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Methodologies to Assess the Bioactivity of an Herbal Extract on Immunity, Health, Welfare and Production Performance in the Chicken: The Case of Melissa officinalis L. Extract

et al. 2021

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“…Also, Mehr et al (2014) found that dietary inclusion of clove oil at 0.15, 0.30 g/kg did not affect antibody titers against NDV and avian influenza in broiler chickens. Moreover, Poorghasemi et al (2017) reported that antibody titers against NDV and IBDV were not affected by dietary lemon balm supplementation in broiler chickens. Additionally, Toghyani et al (2011) stated that antibody titers against avian influenza virus and NDV were not significantly different in broiler chickens fed diets supplemented with 2 g/kg and 4 g/kg of cinnamon bark powder.…”

Section: Resultsmentioning

confidence: 99%

Effects of clove powder supplementation on performance, blood biochemistry, and immune responses in broiler chickens

Al-Mufarrej¹,

Fazea²,

Al-Baadani³

et al. 2019

SA J. An. Sci.

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The goal of this study was to evaluate the effects of clove (Syzygium aromaticum) supplementation levels on performance, blood parameters, and immune response of broilers. A total of 336 one-day-old broilers were assigned to one of eight treatments: 1% to 6% clove supplementation levels, a positive control (vaccinated) and a negative control (unvaccinated). Bodyweight gain, feed intake, feed conversion ratio, serum protein profile, and immune responses were measured weekly. Lymphoid organs were weighed at 21 and 35 days. Levels of dietary clove between 2% and 6% supplementation resulted in a gradual decrease in weight gain and feed intake with an increase in feed conversion ratio at two and three weeks, whereas those that received 4% to 6% supplementation had reduced weight gain and the 3% to 6% supplemented animals consumed the least amount of feed at four and five weeks. High levels of clove supplementation (4%, 5%, and 6%) resulted in reduced total serum protein and albumin and the greatest activity of aspartate aminotransferase at 35 days. Antibodies to viruses against which the birds had been vaccinated were not affected by different levels of clove supplementation compared with the positive control. However, they were increased in birds in the negative control group without vaccination. Relative weights of lymphoid organs were not affected by any treatments at 21 and 35 days. These results indicate that clove supplementation at levels greater than 2% can lead to negative effects on performance without improving the health of the liver and immune responsiveness of broilers.

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“…The total weight of all dissected organs was also calculated. Ratios were calculated according to the following formula: [(weight of component(s)/eviscerated carcass weight) Â 100] (Poorghasemi et al 2017). Carcass components, gastrointestinal organs and heart were measured according to the methods described by Seidavi et al (2014) on 42 nd day of age.…”

Section: Measured Variablesmentioning

confidence: 99%

Feed supplementation with vermi-humus and earthworm (Eisenia foetida) powder on broiler productivity

Chashmidari

Esmaielzadeh

Torshizi

et al. 2021

Italian Journal of Animal Science

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The objective of this study was to evaluate the use of earthworm meal (EW) and vermi-humus (VH) in broiler diets. A total of 225 day-old male broilers were divided into 5 treatment groups with 3 repetitions of 3 birds each. The treatment groups were: T1control (no EW or VH; T2 À 1.0% EW and 0% VH; T3 À 1.0% EW and 1.0% VH; T4 À 1.0% EW and 1.5% VH; and T5: 1.0% EW and 2.0% VH. The birds received (EW) and (VH) for 14 d, and after this period, they received the common diet. The birds were reared for 42 d and, at 42 d, one representative broiler chicken per pen, close to the average body weight, was selected for blood sampling using a sterile needle and heparinised vacuum tube. Performance data, blood results, immunity, ileum morphology and microbiota, the relative weight of carcass components and gastrointestinal organs, malondialdehyde (MDA) content, and breast and thigh meat quality were evaluated. EW and VH had a positive effect on the immune response of broilers, as well as producing a reduction in the aerobic bacteria in the birds' intestines. HIGHLIGHTSProtein is a limiting factor for broiler performance, carcass yield, and meat quality; Poultry industry is searching for new protein sources which can be used on broiler diets; Insects meal are good protein sources in broiler nutrition and can be used on diets without compromising its performance.

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Effect of Dietary Inclusion of Lemon Balm (<i>Melissa Officinalis </i>L.) Extract on Performance, Gut Microflora, Blood Parameters, Immunity and Carcass Traits of Broilers

Cited by 6 publications

References 22 publications

Methodologies to Assess the Bioactivity of an Herbal Extract on Immunity, Health, Welfare and Production Performance in the Chicken: The Case of Melissa officinalis L. Extract

Methodologies to Assess the Bioactivity of an Herbal Extract on Immunity, Health, Welfare and Production Performance in the Chicken: The Case of Melissa officinalis L. Extract

Effects of clove powder supplementation on performance, blood biochemistry, and immune responses in broiler chickens

Feed supplementation with vermi-humus and earthworm (Eisenia foetida) powder on broiler productivity

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