Effect of Dietary Inclusion of Probiotic, Prebiotic and Butyric Acid Glycerides on Resistance against Coccidiosis in Broiler Chickens

Abstract

This research was conducted to investigate the effects of single or combined use of probiotic (Primalac), prebiotic (Fermacto) and butyric acid glycerides (Baby C4) compared to salinomycin on resistance against coccidiosis in broiler chickens challenged with Eimeria. One day-old male Ross 308 broiler chicks were divided into 9 cages with 15 birds per each. Birds of different treatments received a regular corn-soybean meal basal diet supplemented with feed additives; none of them in negative control (C − ), salinomycin in positive control (C ＋ ), probiotic in PRO group, prebiotic in PRE group, butyric acid glycerides in BAG group, probiotic＋prebiotic in PRO＋PRE group, probiotic＋ butyric acid glycerides in PRO＋BAG group, prebiotic＋butyric acid glycerides in PRE＋BAG group, and probiotic ＋prebiotic＋butyric acid glycerides in PRO＋PRE＋BAG group. At 28 d of age, 8 birds from each treatment were removed and kept separately in other cages (2 birds/cage) to challenge with Eimeria. These separated chicks were orally challenged with 1×10 5 E. acervulina and 9×10 4 E. tenella. Positive effect (P＜0.05) was observed in the duodenal and cecal lesion scores in any of the supplemented groups when compared to that of the C − . There was no significant difference between all supplemented groups and C ＋ for cecal lesion score. PRO, PRE＋BAG, PRO＋ PRE, PRO＋BAG and PRO＋PRE＋BAG reduced (P＜0.05) oocyst shedding in birds challenged with Eimeria oocysts compared to the C − , and there was no significant difference between PRO＋PRE, PRO＋BAG, PRO＋PRE ＋BAG and C ＋ . These results demonstrate that prebiotic, butyric acid glycerides and especially probiotic or its combination with prebiotic or butyric acid glycerides enhance the resistance of birds and partially protects against coccidiosis. Therefore, it seems some of these supplements, in comparison to salinomycin, can diminish partially the adverse effects of coccidiosis.

Sodium butyrate in chicken nutrition: the dynamics of performance, gut microbiota, gut morphology, and immunity

“…Mansoub (2011) reported that dietary sodium butyrate increased the weight gain and FCR up to 28 days of age. (Antongiovanni et al, 2007;Leeson et al, 2005;Taherpour et al, 2009). Similarly, butyric acid enhanced the weight gain and FCR (Panda et al, 2009).…”

“…Beneficial health effects of butyrate or butyric acid are well documented, and it has been shown to have positive effects on broiler production parameters such as weight gain, feed intake, and FCR (Antongiovanni et al, 2007;Leeson et al, 2005;Taherpour et al, 2009). Chamba et al (2014) reported that partially coated sodium butyrate in broiler diet significantly increased the feed intake and weight gain, and improved FCR as compared to positive and negative controls during grower and finisher phases but not in the starter phase.…”

Butyric Acid as an Antibiotic Substitute for Broiler Chicken A Review

“…Deconjugated bile acids are less soluble, hence less absorbed in the intestine and are more likely to excrete cholesterol and its fractionin faeces (Klaver and Van der meer, 1993) thus reduction of cholesterol accretion in the body. Previous work done by Taherpour et al (2009), Jang (2011), Mansoub (2011a, Kamal and Ragaa (2014) and Deepa et al (2017) showed reduced levels of serum total and LDL cholesterol without affecting HDL cholesterol level due to addition of various forms of BA. Similarly, serum triglyceride level was also found to be reduced when BAG was supplemented in broiler ration at 0.2 ( Jang, 2011;Mansoub, 2011a) and BA at 0.25 % (Dehghani-Tafti and Jahanian, 2016).…”

Variations on the Efficacy of Probiotics in Poultry

“…demonstrated similar results, with reduction in the total cholesterol and low density lipoprotein (LDL) cholesterol levels (Kalavathy et al, 2003;Taherpour et al, 2009) and triglycerides (Kalavathy et al 2003) in blood serum of broilers.…”