Effect of dietary fiber of “Rihane” barley grains and azoxymethane on serum and liver lipid variables in Wistar rats

Abstract

The aim of the present study is to evaluate the effects of diet enriched with dietary fiber of barley variety "Rihane" and azoxymethane on serum and liver lipid variables in male rats. Forty male rats were divided into four groups and fed on control diet or experimental diet that contained control enriched with dietary fiber of barley variety "Rihane". Animals were injected with saline (controls) or azoxymethane (20 mg/kg body weight s.c.) at 7 and 8 weeks of age. The experimental diet significantly decreased cholesterol level compared with the control diet. Rats fed with BR diet significantly increased the serum high-density lipoprotein (HDL) cholesterol and significantly decreased low-density lipoprotein (LDL) cholesterol concentrations. The experimental diet decreased the atherogenic index (p < 0.05) compared with the control diet. Whereas the azoxymethane induced a significant increase of liver lipid, serum LDL and triglyceride concentrations, but it caused a significant reduction of HDL. Consequently, the ratio of HDL/TC decreased significantly compared with the control (p < 0.05). Accordingly, these results indicated that the diet enriched with dietary fiber of barley variety "Rihane" could be effective in decreasing the atherogenic risk factors in rats whereas the use of the azoxymethane as colon-specific carcinogen substance altered the lipid metabolism.

Dietary fibre alleviates hepatic fat deposition via inhibiting lipogenic gene expression in meat ducks

“…Dietary fibre (DF) plays a critical role in reducing blood TG, cholesterol and hepatic lipid contents and improvement in liver health (Guo et al., ; Lahouar et al., ). Thus, we examined the effects of DF on fat deposition in liver and relative mechanism of DF working for meat ducks from 1 to 14 days.…”

“…Recent studies found that the dietary fibre (DF) could reduce blood TG and cholesterol, and hepatic lipid contents in rodent studies (van Bennekum, Nguyen, Schulthess, Hauser, & Phillips, ; Guo, Shu, & Yang, ; Lahouar et al., ). Similar results have also been reported in the chicken, where DF resulted in lower relative liver weight and/or fat mass (Akiba & Matsumoto, ; Mohiti‐Asli et al., ).…”

Phenolic composition as measured by liquid chromatography/mass spectrometry and biological properties of Tunisian barley

“…[33,34] Recent experiments proved that TBV had considerable protective effects against both cardiovascular disease and colon cancer. [33,35] In the present work, we investigated the antimicrobial capacities of seed ethanolic extracts against five human pathogenic bacteria to search for novel biological activities for the TBV. Our findings (Fig.…”

Pengaruh Konsumsi Serat Pangan Barley Pada Metabolisme Lipid

“…Tunisia, Maroko, Algeria, Afganistan, Lebanon, Cyprus, China, Libya dan Iraq. Rihane adalah salah satu jenis kultivar barley lokal di negara Tunisia yang saat ini mulai banyak diteliti (Lahouar et al, 2011). Penelitian yang berkembang umumnya berkaitan dengan komposisi dan nilai fungsional barley terhadap kesehatan.…”

“…Penelitian yang berkembang umumnya berkaitan dengan komposisi dan nilai fungsional barley terhadap kesehatan. Menurut Kalra et al (2000) (Lahouar et al, 2011;Kalra et al, 2000;Li et al, 2003) dan juga manusia secara langsung (Behall et al, 2004;Shimizu et al, 2008;Telati et al, 2009…”