Effect of dietary esterified glucomannan on performance of broilers exposed to aflatoxin

Abstract

Effect of esterified glucomannan (E-GM), a new generation toxin binder enzymatically extracted from the cell wall of certain stains of Saccharomyces cerevisiae in counteracting the deleterious effects of aflatoxin in broiler chicken was investigated. Broilers fed 1ppm aflatoxin-B1 recorded significantly (P<0.05) poor weekly weight gain, feed consumption, feed efficiency and liveability. Addition of E-GM as a feed additive, in general, in diets free of aflatoxin had no adverse effect on weight gain, feed consumption and feed efficiency except during second week. Addition of E-GM in birds exposed to aflatoxin significantly (P<0.05) counteracted the ill effects on weight gain and feed consumption, while the feed efficiency was restored to normal. High mortality in broilers caused by aflatoxin, was slightly reduced by the addition of E-GM.

Combined toxic effects of aflatoxin B2 and the protective role of resveratrol in Swiss albino mice

“…Although there is no study in the literature about the effect of AFB 2 application on weight gain, there are important data on the effects of other aflatoxin species. Similarly to our results, Arvind and Churchil 39 found that there was a 33.94% reduction in weight gain of chickens fed with 1 ppm AFB 1 for 6 weeks. In another study, Dimitri et al 40 reported that exposure to AFB 1 and AFG 2 caused an average of 539 g (16%) body weight loss in rabbits, and this was related to impaired protein synthesis and DNA synthesis.…”