Effect of Dietary Calcium on Metabolic Balance of Normal Infants

Devizia, B; Fomon, Samuel J.; Nelson, Steven E.; Edwards, Barbara E; Ziegler, Ekhard E.

doi:10.1203/00006450-198508000-00004

Cited by 25 publications

(32 citation statements)

References 27 publications

(30 reference statements)

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“…These high concentrations may lead to lower fractional calcium absorption in the infants. This inverse relationship was demonstrated by Devizia [33] who reported decreasing fractional absorption in a very small group of infants as formula concentration of calcium increased.…”

Section: Full-term Infants E Calciummentioning

confidence: 78%

Vitamin D Deficiency and Calcium Absorption during Childhood

Abrams¹

2011

Vitamin D

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Section: Full-term Infants E Calciummentioning

confidence: 78%

Vitamin D Deficiency and Calcium Absorption during Childhood

Abrams¹

2011

Vitamin D

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“…Its use in term infants is reported to result in lower BMC as measured by photon absorptiometry when compared to infants fed cow milk-based formula [137] or human milk [138]. The phytate in soy formula is thought to be responsible for binding to P and reducing absorption [110,139]. How ever, newer formulation of soy formula with lower protein content and improved mineral suspension ap pears to result in appropriate mineral retention [110] and normal BMC [140,141].…”

Section: Journal Of the American College Of Nutritionmentioning

confidence: 99%

“…In preterm infants fed low-mineral-containing milk, Ca absorption and retention may be increased by vitamin D [77] and P [78,79] supplementation, but the effect of dietary lactose remains unconfirmed [87]. With increasing Ca intake to a level > 150 mg/kg/day, frac tional phosphate absorption is decreased [66], and there is also a 5-10% increase in fecal fat loss noted in preterm [109] and term [110] infants. Fecal Ca excretion also was correlated with fecal fat excretion [79].…”

Section: Determination Of Mineral Requirements In Enterally Fed Infantsmentioning

confidence: 99%

“…The phytate in soy formula is thought to be responsible for binding to P and reducing absorption [110,139]. How ever, newer formulation of soy formula with lower protein content and improved mineral suspension ap pears to result in appropriate mineral retention [110] and normal BMC [140,141]. Nevertheless, until more data are available on soy formula, its use for more than a few days in small preterm infants is inappropriate [142].…”

Section: Journal Of the American College Of Nutritionmentioning

confidence: 99%

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Mineral requirements of low-birth-weight infants.

Koo

Tsang

1991

Journal of the American College of Nutrition

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The minerals calcium (Ca), magnesium (Mg), and phosphorus (P) are essential for tissue structure and function. Recent studies have resulted in a more rational approach to the management of mineral intake in preterm infants receiving parenteral nutrition (PN) and enteral nutrition (EN). For preterm infants requiring PN, the use of PN solutions with a Ca content of 1.25-1.5 mmol/dl (50-60 mg/dl), a P content of 1.29-1.45 mmol/dl (40-45 mg/dl), and an Mg content of 0.2-0.3 mmol/dl (5-7 mg/dl) is supported by studies of mineral homeostasis with serial chemical and calciotropic hormone measurements, standard balance studies, and improved radiographic indices of bone mineralization. For infants requiring EN, an intake of approximately 4 mmol (200 mg) of Ca, 3.2 mmol (100 mg) of P, and 0.33 mmol (8 mg) of Mg/kg/day based on an average retention rate of 64% for Ca, 71% for P, and 50% for Mg should be sufficient to meet the requirements of preterm infants in early infancy. This level of intake is supported by data from balance studies using standard and stable isotope techniques, changes in bone mineral content (BMC) measurements, and calciotropic hormone data. Based on the timing of development of fractures and rickets, changes in BMC, and skeletal growth data, the increased Ca and P intake should continue for at least 3 months after birth or until reaching a body weight of about 3.5 kg. In addition, nonnutritional factors may have the potential to increase mineral loss and disturb mineral homeostasis; chronic diuretic therapy increases mineral loss, and aluminum contamination of nutrients theoretically may compound any skeletal disorder. Thus, attention to the level of mineral intake and factors important in mineral loss and mineral metabolism should optimize mineral retention in small preterm infants.

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“…Estos resultados sugieren que la formula lactea modificada permite ingestion y absorcion de los minerales evaluados, concordantes con las recomendaciones aceptadas habitualmente para lactantes sanos 3 ' 4 ' 6 .…”

Section: Comentark)unclassified

Absorción de minerales de una nueva fórmula Láctea propuesta para el Programa Nacional de Alimentación Complementaria

D¹,

B²,

A³

et al. 1992

Rev. chil. pediatr.

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Mineral absortion in infants fed with a new modified cow's milk formulaCow's miik has excessive calcium and phosphorus content and deficient amounts of zinc and copper, relative to the needs of normal infants. Calcium, phosphorus, magnesium, zinc, and copper absorption with a new cow milk formula which macronutrient and mineral compositions were adapted to comply with most normal infant's requirements, were studied in 9 male infants recovering from malnutrition in a closed nutritional recovery center. Patient's age was 3 to 1 0 months and their weight/length ratio was > 85%. Each infant was fed for six days with unmodified powdered cow's milk diluted to 10%, with sucrose 5%, maltodextrin 1% and vegetable oil 1%added, and for another six days witn modified cow's milk diluted to 1 5% plus maltodextrin 2.5%. Metabolic balance was done in the last three days of each experimental period to every child. Modified milk had lower calcium, magnesium and phosphorus (20%) and higher, copper (60%) and zinc (25%) contents (%) than unmodified milk. Calcium absorption (%) was similar with both unmodified and modified milk [49.0 ± 14.2%vs62.5± 18.6%); absolute calcium absorption with modified milk complied with accepted infant's needs. Apparent phosphorus absorption (54.3 ± 6.7 with modified milk vs 86.8 ± 9.1 mg • kg -d with unmodified milk) should be enough for normal bone mineralization. Net magnesium absorption for modified milk was significantly lower than that of unmodifed milk (3.5 ± 1.2 vs 0.1 + 2.2 mg • kg d; p < 0.001). Copper absorption was deficient with unmodified miik but it was sufficient under modified milk (95.4 + 13.3 jug -kg • d). Both formulae met recommended zinc allowances. The modified milk formula seems to better meet mineral requirements of infants than unmodified powdered cow's milk.Los principals objetivos al desarrollar formumetabolizaci6n y los insuficientes conocimientos las Idcteas, adecuadas a los requerimientos de acerca de los reales requerimientos de estos numinerales del primer ano de vida, son promover trientes. La leche de vaca, sin considerar la bioun crecimiento y desarrollo psicomotor normal, disponibilidad de los minerales, tiene un conteasegurar una mineralizaci6n osea adecuada y nido teorico cercano al adecuado de zinc, excemantener una respuesta inmune dptima 1 ' 2 . sivo de otros (calcio, f6sforo), e insuficiente de Entre los factores que dificultan en la actualidad otros (cobre,magnesio) 1~i°.una recomendaci6n mis exacta, en cuanto al En la formulation de una leche de vaca en aporte de minerales, estan las multiples interacpolvo modificada (LPM), que ha sido propuesta ciones entre minerales, o con otros nutrientes, para incorporar en el Programa Nacional (chileque pueden modificar su biodisponibilidad o su no) de Alimentation Complementaria (PNAC), se han efectuado cambios en la concentraci6n de algunos minerales y tambie"n de otros nu-1. Material y MetodosSe seleccionaion lactantes con desnutricion primaria, hospitalizados para su tratamiento enun centro cerrado de recuperacion nu...

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Effect of Dietary Calcium on Metabolic Balance of Normal Infants

Cited by 25 publications

References 27 publications

Vitamin D Deficiency and Calcium Absorption during Childhood

Vitamin D Deficiency and Calcium Absorption during Childhood

Mineral requirements of low-birth-weight infants.

Absorción de minerales de una nueva fórmula Láctea propuesta para el Programa Nacional de Alimentación Complementaria

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