Absorción de minerales de una nueva fórmula Láctea propuesta para el Programa Nacional de Alimentación Complementaria

Abstract

Mineral absortion in infants fed with a new modified cow's milk formulaCow's miik has excessive calcium and phosphorus content and deficient amounts of zinc and copper, relative to the needs of normal infants. Calcium, phosphorus, magnesium, zinc, and copper absorption with a new cow milk formula which macronutrient and mineral compositions were adapted to comply with most normal infant's requirements, were studied in 9 male infants recovering from malnutrition in a closed nutritional recovery center. Patient's age was 3 to 1 0 months and their weight/length ratio was > 85%. Each infant was fed for six days with unmodified powdered cow's milk diluted to 10%, with sucrose 5%, maltodextrin 1% and vegetable oil 1%added, and for another six days witn modified cow's milk diluted to 1 5% plus maltodextrin 2.5%. Metabolic balance was done in the last three days of each experimental period to every child. Modified milk had lower calcium, magnesium and phosphorus (20%) and higher, copper (60%) and zinc (25%) contents (%) than unmodified milk. Calcium absorption (%) was similar with both unmodified and modified milk [49.0 ± 14.2%vs62.5± 18.6%); absolute calcium absorption with modified milk complied with accepted infant's needs. Apparent phosphorus absorption (54.3 ± 6.7 with modified milk vs 86.8 ± 9.1 mg • kg -d with unmodified milk) should be enough for normal bone mineralization. Net magnesium absorption for modified milk was significantly lower than that of unmodifed milk (3.5 ± 1.2 vs 0.1 + 2.2 mg • kg d; p < 0.001). Copper absorption was deficient with unmodified miik but it was sufficient under modified milk (95.4 + 13.3 jug -kg • d). Both formulae met recommended zinc allowances. The modified milk formula seems to better meet mineral requirements of infants than unmodified powdered cow's milk.Los principals objetivos al desarrollar formumetabolizaci6n y los insuficientes conocimientos las Idcteas, adecuadas a los requerimientos de acerca de los reales requerimientos de estos numinerales del primer ano de vida, son promover trientes. La leche de vaca, sin considerar la bioun crecimiento y desarrollo psicomotor normal, disponibilidad de los minerales, tiene un conteasegurar una mineralizaci6n osea adecuada y nido teorico cercano al adecuado de zinc, excemantener una respuesta inmune dptima 1 ' 2 . sivo de otros (calcio, f6sforo), e insuficiente de Entre los factores que dificultan en la actualidad otros (cobre,magnesio) 1~i°.una recomendaci6n mis exacta, en cuanto al En la formulation de una leche de vaca en aporte de minerales, estan las multiples interacpolvo modificada (LPM), que ha sido propuesta ciones entre minerales, o con otros nutrientes, para incorporar en el Programa Nacional (chileque pueden modificar su biodisponibilidad o su no) de Alimentation Complementaria (PNAC), se han efectuado cambios en la concentraci6n de algunos minerales y tambie"n de otros nu-1. Material y MetodosSe seleccionaion lactantes con desnutricion primaria, hospitalizados para su tratamiento enun centro cerrado de recuperacion nu...