Effect of dialysate volume on peritoneal dialysis kinetics

Goldschmidt, Z; Pote, Harry H.; Katz, Murray A.; Shear, Leroy

doi:10.1038/ki.1974.29

Cited by 43 publications

(7 citation statements)

References 12 publications

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“…The loss was greater in the group with the higher predialysis plasma levels and this comparison proved to be statistically very significant (p< 0.001). Tak ing for granted that the other factors influencing the peri toneal dialysis remain stable, this fact is due to the gradient [Goldsmith et al 1974;Gross et al 1967;Tsapas et al 1975].…”

Section: Discussionmentioning

confidence: 99%

Effect of Peritoneal Dialysis on Plasma Levels of Ascorbic Acid

Tsapas¹,

Magoula²,

Paletas³

et al. 1983

Nephron

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The effect of peritoneal dialysis on plasma ascorbate levels was investigated in 32 patients suffering from end-stage renal disease. Our studies demonstrated a high peritoneal clearance of ascorbic acid resulting in a significant loss into the dialysate. The quantity of ascorbic acid lost by patients undergoing peritoneal dialysis was proportional to the predialysis ascorbic acid levels. Since the ascorbic acid lost from the plasma during peritoneal dialysis is not adequately replaced by dietary consumption of vitamin C, patients undergoing chronic peritoneal dialysis should receive ascorbic acid supplementation as an important part of their therapeutic regimen.

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Section: Discussionmentioning

confidence: 99%

Effect of Peritoneal Dialysis on Plasma Levels of Ascorbic Acid

Tsapas¹,

Magoula²,

Paletas³

et al. 1983

Nephron

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“…Generally there are two main reasons thought to cause this inverse relationship between volume and D / P urea and creatinine. The first is that larger volumes of dialysate require somewhat longer time to reach equivalent D / P solute, most notable during the first 2 hours (13–15). Potential remedies to this problem in the future might be a cycler or catheter that allows better mixing of the dialysate and increases contact time with the peritoneal membrane.…”

Section: Percentage Increase In Clearances With Increase In Exchange mentioning

confidence: 99%

Automated Peritoneal Dialysis Symposium: Intra‐abdominal Pressure, Peritoneal Dialysis Exchange Volume, and Tolerance in APD

Enoch

Aslam

Piraino

2002

Seminars in Dialysis

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Automated peritoneal dialysis (APD) is increasingly popular compared to continuous ambulatory peritoneal dialysis (CAPD). It not only can provide more solute clearance and ultrafiltration than its CAPD counterpart, but it is conducive to a more convenient lifestyle as well. Using relatively smaller-volume daytime dwells, with the use of larger-volume exchanges while the patient is recumbent during the night, is an attractive approach. Advantages of supine exchanges include greater small molecule clearances for equivalent flow rates and decreased intra-abdominal pressure per volume of dialysate (as intraperitoneal pressure parallels intraperitoneal volume). Urea nitrogen clearance can be optimally increased on APD by increasing both the exchange volume and the frequency of exchanges at night. This is even true for anuric low transporters. This approach allows daytime exchanges and volumes to be minimized. Historic studies in peritoneal dialysis including flow rate analysis, clearance and adequacy studies, as well as tolerance have primarily involved CAPD. As a result, there is a paucity of investigations involving APD. More research is required in APD related to these subjects.

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“…It must be remembered that it is not convenient to overfill the peritoneal cavity: in fact, the time required to achieve equilibrium between the peritoneal solution and serum increases in proportion to the volume of liquid used, this is probably due to changes in the volume/surface ratio [13].…”

Section: Methodsmentioning

confidence: 99%

Acceleration of Peritoneal Dialysis with Simple Device

Paolo¹,

Acconcia²,

Manganelli³

1977

Nephron

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Peritoneal dialysis in acute and chronic renal failure has been greatly facilitated by the advent of Tenckhoff indwelling peritoneal catheters and by strict control of peritoneal infections. A number of reports on long-term treatment have been published. A simple device has been developed and tested for regular peritoneal dialysis in the hospital and in the home, in order to accelerate the time required. Employing a ‘single needle apparatus’, a rotary pump and a thermostatic heating unit, it is possible to carry out a very efficacious peritoneal dialysis, similar to the ‘continuous peritoneal dialysis’. The purpose of this paper is to discuss its use and its advantages in comparison with classic procedures.

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Effect of dialysate volume on peritoneal dialysis kinetics

Cited by 43 publications

References 12 publications

Effect of Peritoneal Dialysis on Plasma Levels of Ascorbic Acid

Effect of Peritoneal Dialysis on Plasma Levels of Ascorbic Acid

Automated Peritoneal Dialysis Symposium: Intra‐abdominal Pressure, Peritoneal Dialysis Exchange Volume, and Tolerance in APD

Acceleration of Peritoneal Dialysis with Simple Device

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