Acceleration of Peritoneal Dialysis with Simple Device

Abstract

Peritoneal dialysis in acute and chronic renal failure has been greatly facilitated by the advent of Tenckhoff indwelling peritoneal catheters and by strict control of peritoneal infections. A number of reports on long-term treatment have been published. A simple device has been developed and tested for regular peritoneal dialysis in the hospital and in the home, in order to accelerate the time required. Employing a ‘single needle apparatus’, a rotary pump and a thermostatic heating unit, it is possible to carry out a very efficacious peritoneal dialysis, similar to the ‘continuous peritoneal dialysis’. The purpose of this paper is to discuss its use and its advantages in comparison with classic procedures.

Effect of Chlorpromazine on Peritoneal Clearances

“…The same directional change of ultrafiltration and solute transport indicate a simple effect on peritoneal surface rather than a complex intramembranous alteration found in many conditions [19]. In addition, the results of different techniques used to stir the stagnant dialysate fluid layers in other studies [20,21] were the same as in this study. The stable protein loss in this experiment can be explained by the fact that proteins are charged molecules of large molecular weight with high reflection coefficient and hardly influences by dialysate composition [22].…”

A New Technique – Semicontinuous Rapid Flow, High Volume Exchange – For Effective Peritoneal Dialysis in Shorter Periods

“…It is clear from the observations that our method of semicontinuous rapid flow, high volume ex change peritoneal dialysis is superior to the methods used by Tenckhoff et al [1965] and Paolo et al [1977] as shown in table V.…”

“…In the study of Paolo et al [1977] on rapid flow peri toneal dialysis, peritoneal clearance of urea and creatinine at 6 litres/hour was 34.0 + 3 and 22.0±3.00 ml/minute, respectively. But these values are significantly lower than the values obtained in our study.…”

“…Later, Tenckhoff et al [1965] and Paolo et al [1977] attempted to increase the flow rate of dialysate, thereby improving the clearance rate. Various techniques are used to increase the peritoneal clearances along with our method as shown in figure 2.…”

“…The incidence was not related to flow rates but depended on the patient's condition. Semicontinuous rapid flow, low volume exchange [Paolo et al, 1977] 34.0 ± 3.00 22.0 ± 3.00…”