Effect of dead volume on efficiency of a gas chromatographic system

Abstract

also necessitates a conservation of "mass" indicating, for a constant sample size, an isosbestic point in the data curves.3. If the points lie in a straight line, one can determine a reaction rate constant, k, for A = B from the spacing of the points.4. If the points fall on a line through the origin, the proportion of A and B is constant and the sample size is changing. The distance from the origin along this line is proportional to the sample size. 5. If one uses a constant sample size and runs an unknown mixture and successive dilutions of this mixture with one component, the composition of the unknown mixture can be determined from its distance from the boundaries along a line parallel to 9. Figure 10 is an example for a 50:50 "unknown" mixture of A and B. Three other samples are prepared by sequential dilutions (1:1) withIf the sample size is not constant, the points will not be in a line, but the analysis can still be obtained by passing line 9 through each original sample point and measuring as above. ACKNOWLEDGMENTThe discussions with William Lawton and the help of Paul Taylor with some of the experimental work and with the final drawings are greatly appreciated.

Equations for calculation of chromatographic figures of merit for ideal and skewed peaks

“…Although somewhat surprising, this is explained by the near convergence of these EMG equations to Gaussian ones when the substitution B/A = 1.00 is made in the former. The NSYS equation in Table III, for example, becomes iVSYS = 18.53(iR/W0.i)2 (13) which is within +0.6% of the Gaussian formula NWoi = 18.42(tR/W0.1)2 ( 14)…”

Measurement of diffusion coefficients of octane isomers by the chromatographic broadening method

“…25 Temperatures at any point in the oven could be held to rt0.02". Our system resembled the one described by Fuller, Ensley, and Giddings.13 Several modifications, however, were made in order to increase the precision of measurement.…”

Fundamental Relationships of Chromatography

“…contribution to the plate height from molecular diffusion in the mobile phase arises from the natural tendency of the solute band to diffuse away from the zone center as it moves through the column [59,60,63,64]. Its value is proportional to the diffusion coefficient and the time the sample spends in the column.…”