Effect of Cyperus rotundus tubers ethanolic extract on learning and memory in animal model of Alzheimer

Rabiei, Zahra; Hojjati, Mohammad Reza; Rafieian-Kopaeia, Mahmoud; Alibabaei, Zahra

doi:10.1016/j.biomag.2013.08.006

Cited by 34 publications

(13 citation statements)

References 26 publications

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“…37 The red color of pomegranate juice has been attributed to anthocyanins, such as cyanidin, pelargonidin glycosides, and delphinidin, which have potent antioxidant activity. 37 Preclinical and clinical researches have revealed that plants antioxidants are effective in prevention and treatment of free radical-induced complications such as low-density lipoprotein oxidation, 58,59 heart disease, 60,61 diabetes, 62,63 cancer, 64,65 cognition problem, 66,67 and infectious diseases. [68][69][70] Therefore, the medicinal properties of pomegranate, at least in part, can be attributed to its components with antioxidant activities.…”

Section: Discussionmentioning

confidence: 99%

A Review Study on Punica granatum L

Shaygannia

Bahmani

Zamanzad

et al. 2015

J Evid Based Complementary Altern Med

174

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Punica granatum L (pomegranate) is a deciduous shrub, native to Iran. Nowadays, besides its use as a fruit, its medicinal properties have attracted the interest of researchers of many countries. Pomegranate fruit has medicinal properties such as antiinflammatory and antibacterial activities. The pomegranate seed oil has inhibitory effect on skin and breast cancers. The pomegranate seed oil has phytoestrogenic compounds and the fruit is rich in phenolic compounds with strong antioxidant activity. Ellagic acid is one of the main components of pomegranate with phenolic structure and antioxidant activity. This review article presents the recently published findings on different aspects of this plant focusing on its medicinal properties

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Section: Discussionmentioning

confidence: 99%

A Review Study on Punica granatum L

Shaygannia

Bahmani

Zamanzad

et al. 2015

J Evid Based Complementary Altern Med

174

View full text Add to dashboard Cite

show abstract

“…Four extracts of leaves extracts showed no antigenotoxic effect on the indicator bacteria. Rabiei et al [15] carried out the ethanolic extract of tubers of plant effects on learning and memory in rat model of Alzheimer. All nucleus basalis of Meynert-lesioned rats demonstrated significant cognitive deficits along with the Morris water maze swimming test.…”

Section: Resultsmentioning

confidence: 99%

Volatiles of Turkish Cyperus rotundus L. Roots

Poyraz¹,

Demirci²,

Küçük³

2018

Rec.Nat.Prod.

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Purple nutsedge, Cyperus rotundus L. (Cyperaceae) is an invasive plant grown in all around the world. C. rotundus rhizomes are called "topalak" and an analgesic plant for the treatment of stomach ache in infants, folk medicine in Turkey. The volatile compounds of C. rotundus rhizomes were investigated by Headspace-SPME. Cyperene (30.5% and 28.0%), α-copaene (10.6% and12%) and α-ylangene (7.7% and10.5%) were identified as main volatile components of rhizomes and analyzed at room temperature and 40ºC respectively. This study designed to support detailed studies on underground plant parts volatiles and it is the first time to identification of volatile compounds of raw C. rotundus rhizomes collected from Turkey by Headspace-SPME and GC and GC-MS.

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“…About each individual herbal plant, which DL contains, some evidence exists about their effect on cognition and memory, in particular in animal models. Rabiei et al 24 studied the influence of C. rotundus L. (Cyperaceae) tubers ethanolic extract on learning and memory in the rat model of Alzheimer's and intact rats. They randomly divided 49 male Wistar rats into seven groups.…”

Section: Discussionmentioning

confidence: 99%

“…[19][20][21] In traditional medicine both DL and its components have been used for reinforcement of memory. [16][17][18][19][20][21] Various studies have investigated the efficacy of components of DL in the treatment of Alzheimer's disease [22][23][24][25][26][27] but there is no study about the efficacy of DL in treatment of Alzheimer's disease. So far, no study has been done to determine the clinical efficacy of DL in patients with Alzheimer's disease.…”

Section: Introductionmentioning

confidence: 99%