Effect of creatine supplementation on sprint exercise performance and muscle metabolism

Abstract

The aim of the present study was to examine the effect of creatine supplementation (CrS) on sprint exercise performance and skeletal muscle anaerobic metabolism during and after sprint exercise. Eight active, untrained men performed a 20-s maximal sprint on an air-braked cycle ergometer after 5 days of CrS [30 g creatine (Cr) + 30 g dextrose per day] or placebo (30 g dextrose per day). The trials were separated by 4 wk, and a double-blind crossover design was used. Muscle and blood samples were obtained at rest, immediately after exercise, and after 2 min of passive recovery. CrS increased the muscle total Cr content (9.5 +/- 2.0%, P < 0.05, mean +/- SE); however, 20-s sprint performance was not improved by CrS. Similarly, the magnitude of the degradation or accumulation of muscle (e.g., adenine nucleotides, phosphocreatine, inosine 5'-monophosphate, lactate, and glycogen) and plasma metabolites (e.g. , lactate, hypoxanthine, and ammonia/ammonium) were also unaffected by CrS during exercise or recovery. These data demonstrated that CrS increased muscle total Cr content, but the increase did not induce an improved sprint exercise performance or alterations in anaerobic muscle metabolism.

Suplementação com creatina altera a potência no teste de Wingate mas eleva a concentração de creatinina

“…one adopted in the present study, which may have caused increase in the P med . However, this finding contrasts with the ones observed in a study carried out in 20s 11 and 15s tests 10 . These authors did not report alteration in this variable after the use of CrS.…”

“…The result of the W30 test of the present study contrasts with the previous studies 6,11 , which did not identify significant alterations in P max during high-intensity and short duration test in the cycle ergometer after the CrS use. However, these authors used a protocol which consisted only of one stimulus and did not perform repeated stimuli which can cause the PCr depletion according to the present study, in which the 10s test was used.…”

Suplementação com creatina altera a potência no teste de Wingate mas eleva a concentração de creatinina

“…one adopted in the present study, which may have caused increase in the P med . However, this finding contrasts with the ones observed in a study carried out in 20s 11 and 15s tests 10 . These authors did not report alteration in this variable after the use of CrS.…”

“…The result of the W30 test of the present study contrasts with the previous studies 6,11 , which did not identify significant alterations in P max during high-intensity and short duration test in the cycle ergometer after the CrS use. However, these authors used a protocol which consisted only of one stimulus and did not perform repeated stimuli which can cause the PCr depletion according to the present study, in which the 10s test was used.…”

Creatine reduces human muscle PCr and pH decrements and Piaccumulation during low-intensity exercise

“…During the Cr supplementation period, the ATP values remained unchanged, which is in agreement with the results of other studies (4,10,13,19,21,22,43). Despite the comparatively low daily dose of Cr given in the present study, intramuscular PCr increased 1.3 mmol/kg wet wt after 9 days of Cr feeding.…”

Short-term creatine supplementation does not improve muscle activation or sprint performance in humans

“…The unchanged performance after Cr supplementation is also consistent with numerous other reports (Balsom et al 1993;Cooke et al 1995;Cooke and Barnes 1997;Odland et al 1997;Snow et al 1998), even when total muscle Cr content was elevated (Odland et al 1997;Snow et al 1998). If any ergogenic effect occurred with Cr supplementation, it may have been lower than the sensitivity of the intermittent test protocol.…”

Suplementação com creatina altera a potência no teste de Wingate mas eleva a concentração de creatinina

“…one adopted in the present study, which may have caused increase in the P med . However, this finding contrasts with the ones observed in a study carried out in 20s 11 and 15s tests 10 . These authors did not report alteration in this variable after the use of CrS.…”

“…The result of the W30 test of the present study contrasts with the previous studies 6,11 , which did not identify significant alterations in P max during high-intensity and short duration test in the cycle ergometer after the CrS use. However, these authors used a protocol which consisted only of one stimulus and did not perform repeated stimuli which can cause the PCr depletion according to the present study, in which the 10s test was used.…”

Creatine reduces human muscle PCr and pH decrements and Piaccumulation during low-intensity exercise

“…During the Cr supplementation period, the ATP values remained unchanged, which is in agreement with the results of other studies (4,10,13,19,21,22,43). Despite the comparatively low daily dose of Cr given in the present study, intramuscular PCr increased 1.3 mmol/kg wet wt after 9 days of Cr feeding.…”

Short-term creatine supplementation does not improve muscle activation or sprint performance in humans

“…The unchanged performance after Cr supplementation is also consistent with numerous other reports (Balsom et al 1993;Cooke et al 1995;Cooke and Barnes 1997;Odland et al 1997;Snow et al 1998), even when total muscle Cr content was elevated (Odland et al 1997;Snow et al 1998). If any ergogenic effect occurred with Cr supplementation, it may have been lower than the sensitivity of the intermittent test protocol.…”

Suplementação com creatina altera a potência no teste de Wingate mas eleva a concentração de creatinina

“…one adopted in the present study, which may have caused increase in the P med . However, this finding contrasts with the ones observed in a study carried out in 20s 11 and 15s tests 10 . These authors did not report alteration in this variable after the use of CrS.…”

“…The result of the W30 test of the present study contrasts with the previous studies 6,11 , which did not identify significant alterations in P max during high-intensity and short duration test in the cycle ergometer after the CrS use. However, these authors used a protocol which consisted only of one stimulus and did not perform repeated stimuli which can cause the PCr depletion according to the present study, in which the 10s test was used.…”

Creatine reduces human muscle PCr and pH decrements and Piaccumulation during low-intensity exercise

“…During the Cr supplementation period, the ATP values remained unchanged, which is in agreement with the results of other studies (4,10,13,19,21,22,43). Despite the comparatively low daily dose of Cr given in the present study, intramuscular PCr increased 1.3 mmol/kg wet wt after 9 days of Cr feeding.…”

Short-term creatine supplementation does not improve muscle activation or sprint performance in humans

“…The unchanged performance after Cr supplementation is also consistent with numerous other reports (Balsom et al 1993;Cooke et al 1995;Cooke and Barnes 1997;Odland et al 1997;Snow et al 1998), even when total muscle Cr content was elevated (Odland et al 1997;Snow et al 1998). If any ergogenic effect occurred with Cr supplementation, it may have been lower than the sensitivity of the intermittent test protocol.…”