Effect of cortical bone micro-structure in fragility fracture patients on lamellar stress

Ascenzi, Maria-Grazia; Zonca, A.; Keyak, Joyce H.

doi:10.1016/j.jbiomech.2019.109596

Cited by 7 publications

(4 citation statements)

References 22 publications

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“…In addition to changes in bone volume, changes in bone quality following fracture may also have an effect on bone strength and fracture risk. For example, previous studies in humans found that women who had low-trauma fractures in the absence of low BMD had significantly different lamellar width and osteonal structure than age-matched women without prevalent fractures [16,17]. In the current study we observed a small but significant decrease (~1%) in TMD in vertebral trabecular bone of Young mice following fracture.…”

Section: Discussionsupporting

confidence: 58%

Region-dependent bone loss in the lumbar spine following femoral fracture in mice

Ely

Osipov

Emami

et al. 2020

Bone

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Section: Discussionsupporting

confidence: 58%

Region-dependent bone loss in the lumbar spine following femoral fracture in mice

Ely

Osipov

Emami

et al. 2020

Bone

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“…Almost all of the elements were significantly different in all parts, and the Ca/P ratio in the middle part of the diaphysis was found to be significantly lower than of the proximal and distal parts. Increasing calcification in bone tissue results in increased stress and decreased strain levels (Ascenzi et al, 2020). It is possible that the bone stress at the middle part of the diaphysis might have been lower than at the proximal and distal parts.…”

Section: Discussionmentioning

confidence: 99%

Elements May Not Be Homogenously Distributed throughout The Bone, an Issue of Concern When Using X-Ray Fluorescence in Species Classification

Pitakarnnop¹,

Buddhachat²,

Piboon³

et al. 2020

CMUJNS

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One major question that arises when we talk about the elements in bones is whether all bones contain the same elements. This study was implemented to answer this question and determine what the elemental levels are in the femur bones of pigs using the handheld X-ray fluorescence technique. Ten dry femur bones taken from adult domestic pigs (Sus scrofa domesticus) were scanned using a handheld XRF analyzer. We compared three different groups in this study. First, comparisons were made between six locations of the whole femur bones as follows; compact bone at diaphysis (CD), compact bone at epiphysis (CE), spongy bone at diaphysis (SD), spongy bone at femoral head (SFH), spongy bone at femoral trochlea (SFT) and spongy bone at metaphysis (SM). Second, the different parts of the compact bones at the diaphysis were compared (proximal, middle and distal), Third, comparisons were made among four directions at the diaphysis (cranial, caudal, lateral and median). Differences in the elemental percentages and Ca/P ratio among all locations were determined by one-way ANOVA. The presence of most of the detected

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“…FEM has been well known and widely used to simulate cortical bone fracture under mode-I, mode-II, and mixed-mode fracture analysis. 12–14,65–67,87–91 However, XFEM was also used widely in some recent studies in multiscale modeling, anisotropic modeling, heterogeneous modeling, and fracture analysis of cortical bone. 92–96 In the recent study, Kumar et al 19 compared the numerically predicted and experimentally determined the K IC of cortical bone in longitudinally and transversely fractured orientation and stated that K IC in the transversely fractured specimen was more as compared to the longitudinally fractured specimen.…”

Section: Experimental and Numerical Analysis Of Cortical Bone Fractur...mentioning

confidence: 99%

A review on experimental and numerical investigations of cortical bone fracture

Kumar

Ghosh

2022

Proc Inst Mech Eng H

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This paper comprehensively reviews the various experimental and numerical techniques, which were considered to determine the fracture characteristics of the cortical bone. This study also provides some recommendations along with the critical review, which would be beneficial for future research of fracture analysis of cortical bone. Cortical bone fractures due to sports activities, climbing, running, and engagement in transport or industrial accidents. Individuals having different diseases are also at high risk of cortical bone fracture. It has been observed that osteon orientation influences cortical bone fracture toughness and fracture mechanisms. Apart from this, recent studies indicate that fracture parameters of cortical bone also depend on many factors such as age, sex, temperature, osteoporosis, orientation, location, loading condition, strain rate, and storage facility, etc. The cortical bone regains its fracture toughness due to various toughening mechanisms. Owing to these factors, several experimental, clinical, and numerical investigations have been carried out to determine the fracture parameters of the cortical bone. Cortical bone is the dense outer surface of the bone and contributes to 80%–82% of the skeleton mass. Cortical bone experiences load far exceeding body weight due to muscle contraction and the dynamics of motion. It is very important to know the fracture pattern, direction of fracture, location of the fracture, and toughening mechanism of cortical bone. A basic understanding of the different factors that affect the fracture parameters and fracture mechanisms of the cortical bone is necessary to prevent the failure and fracture of cortical bone. This review has summarized the advancement considered in the various experimental techniques and numerical methods to get complete information about the fracture mechanisms of cortical bone.

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Effect of cortical bone micro-structure in fragility fracture patients on lamellar stress

Cited by 7 publications

References 22 publications

Region-dependent bone loss in the lumbar spine following femoral fracture in mice

Region-dependent bone loss in the lumbar spine following femoral fracture in mice

Elements May Not Be Homogenously Distributed throughout The Bone, an Issue of Concern When Using X-Ray Fluorescence in Species Classification

A review on experimental and numerical investigations of cortical bone fracture

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