Effect of Corneal Drying on Central Corneal Thickness

Dayanir, Volkan; Sakarya, Rabia; Özçura, Fatih; Kır, Erkin; Aktunç, Turgay; Ozkan, Bahar Seyhan; Okyay, Pınar

doi:10.1097/00061198-200402000-00002

Cited by 42 publications

(27 citation statements)

References 16 publications

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“…Previous studies showed a decrease in CCT in dry-eye syndrome, because of the osmolality of tear film and hypertonic tear film. 8,9 According to our results, a decrease in CCT is not related with corneal biomechanical changes in dry eye. In another study, an increase in CCT values was seen at night but corneal viscoelasticity did not change.…”

Section: Discussionmentioning

confidence: 55%

“…7 Another factor is central corneal thickness (CCT), which is shown to be decreased in dry eye. 8,9 The consensus is that IOP measurement using GAT may be falsely reduced in patients with thin corneas. 7 All these corneal changes seen in dry eye can affect the corneal viscoelasticity, which can be measured with the Ocular Response Analyser (ORA; Reichert Ophthalmic Instruments, Buffalo, NY, USA).…”

Section: Introductionmentioning

confidence: 99%

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Corneal hysteresis in patients with dry eye

Fırat

Doğanay

2011

Eye

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Section: Discussionmentioning

confidence: 55%

Section: Introductionmentioning

confidence: 99%

Corneal hysteresis in patients with dry eye

Fırat

Doğanay

2011

Eye

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“…Third, all IOP measurements using the three tonometers were taken after instillation of anesthetic drops, which may change the corneal biomechanical parameters. 17 However, in the IOPen learning curve, we found that without corneal anesthesia, the IOPen was uncomfortable for most subjects. Also the drops were instilled before the IOP measurements and the influence for the corneal properties modifications is similar for all tonometers.…”

Section: Gendermentioning

confidence: 84%

Comparation of the new rebound tonometer IOPen and the Goldmann tonometer, and their relationship to corneal properties

Moreno-Montañés

Gosende

Caire

et al. 2010

Eye

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Purpose To compare the intraocular pressures (IOPs) obtained with the IOPen rebound tonometer, Goldmann applanation tonometer (GAT) and the ocular response analyzer (ORA) and investigate the effects of corneal biomechanical properties on IOPen measurements. Methods A total of 198 normal eyes were included in this cross-sectional and randomized study. Three measurements were taken using IOPen. Agreement between tonometers was calculated using the Bland and Altman limits of agreement (LoA) analysis. Results The median IOPen IOP was 3 mm Hg below the GAT (Po0.001), 3 mm Hg below the ORA IOP similar to Goldmann (IOPg), and 3 mm Hg below the ORA IOP corrected using corneal parameters (IOPcc)(Po0.01). The LoA width between the IOPen and GAT IOPs varied between 13.92 (mean IOPen IOP) and 15.99 mm Hg (third IOPen measurement). The central corneal thickness (CCT) was unrelated to IOPen measurements (P40.05). Corneal hysteresis (CH) and corneal rigidity factor (CRF) were correlated with IOPen and GAT. Conclusions IOPen underestimated the IOP compared with GAT and ORA. The effect of measurement quality or measurement order on IOPen was low. CCT did not affect the IOPen, but the CH and CRF did. The LoA width between the IOPen and GAT IOPs was higher than between the ORA IOPg or ORA IOPcc and GAT IOPs.

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“…9,10,11,13 In our study dry eye tests were not taken into consideration when comparing groups so we do not know how many patients have dry eye which may affect CCT as some studies show lower CCT in dry eye patients. 25,26 One of the limitations of this study is that the systemic therapy of patients are unknown. We do not know medications that patients currently use or used in the past that may have an effect on ORA parameters directly or indirectly by influencing IOP and CCT.…”

Section: Discussionmentioning

confidence: 97%