Effect of consuming fiber from corn bran, soy hulls, or apple powder on glucose tolerance and plasma lipids in type II diabetes

Abstract

The effects of consuming corn bran, soy hulls, or apple powder on glucose and lipid metabolism were investigated in two studies of persons with type II diabetes. Fiber sources, completely or partially added to bread, were incorporated into subjects' self-selected diets. Low fiber white bread served as a control. In study A, 10 subjects consumed 26 g fiber source daily; in study B, eight subjects consumed 52 g fiber source. Biochemical tests, including a 2-h postprandial glucose test using a low fiber formula meal, were scheduled after 2 and 4 wk of each dietary treatment. Soy hull consumption slightly improved some measures of glucose tolerance, with results varying between the studies. Consumption of 52 g corn bran decreased very low-density lipoprotein cholesterol, triglycerides, and glycosylated Hb, but subject tolerance was poor with the particle size used. Consumption of 52 g apple powder increased low-density lipoprotein and total cholesterol levels.

Soyfood consumption and risk of glycosuria: a cross-sectional study within the Shanghai Women's Health Study

“…Animal studies have demonstrated that soy protein and soy isoflavones improve glycemic control, lower insulin requirement, and increase insulin sensitivity (Vahouny et al, 1985;Iritani et al, 1997;Wagner et al, 1997;Lavigne et al, 2000). Similar benefits have also been documented in several intervention studies with soy supplements (soy protein, soy fiber, and soy isoflavones), but results have been inconsistent (Mahalko et al, 1984;Lo et al, 1986;Hermansen et al, 2001;Jayagopal et al, 2002). One cross-sectional study has examined the effect of usual dietary intake of isoflavones on glucose metabolism and observed an inverse association with insulin level (Goodman-Gruen & Kritz-Silverstein, 2001).…”

Beneficial Effects of a Soy-Based Dietary Supplement on Lipid Levels and Cardiovascular Risk Markers in Type 2 Diabetic Subjects

“…A very modest improvement in blood glucose attributed to fiber intake from soy beans has been reported in type 2 diabetic subjects both in some acute (17) and some more long-term experiments (36), while this was not seen in other studies (37). No change in insulin levels occurred (17,38).…”

Pharmaceutical Prospects of Phytoestrogens

“…Many studies in animals as well as in humans suggest that soy has beneficial effects on diabetes mellitus, and several studies in obese humans and animals suggest that soy as a source of dietary protein has significant antiobesity effects (Table 2) [103][104][105][106][107][108][109][110][111][112][113][114][115][116][117]. Mahalko et al fed different sources of fiber to type 2 diabetic subjects for 2 to 4 weeks and observed beneficial effects of soy hulls on glucose tolerance, lipid indexes, and glycated hemoglobin [110].…”

“…Mahalko et al fed different sources of fiber to type 2 diabetic subjects for 2 to 4 weeks and observed beneficial effects of soy hulls on glucose tolerance, lipid indexes, and glycated hemoglobin [110]. Tsai et al observed that in obese subjects with type 2 diabetes, soy polysaccharides significantly reduced increases in postprandial serum glucose and triacylglycerol concentrations [108].…”