Effect of collagen type I and vitamin D3 functionalization of biomimetic bioglass scaffolds on hydroxyapatite condensation

Abad-Javier, Mario E.; Cajero-Juárez, Marcos; Núñez-Anita, Rosa Elvira; Contreras-Garcı́a, M.E.

doi:10.1016/j.jeurceramsoc.2019.02.050

Cited by 4 publications

(2 citation statements)

References 17 publications

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“…The band located at 812 cm −1 corresponds to the presence of aromatic rings, especially an alkane ring with six C atoms with three substitutions, of which the VD3 molecule has two in its structure. Between 1310 and 1000 cm −1 , the bands corresponding to C-C and C-O bonds can be found, which are related to aliphatic chains and a hydroxyl group that form the molecular structure of VD3 [40]. At the same time, cholecalciferol is characterized by the asymmetric CH 3 and symmetric CH 2 stretching modes at 2928 cm −1 and 2860 cm −1 , respectively [41].…”

Section: Surface Investigation Of As-deposited Thin Filmsmentioning

confidence: 96%

“…Two other characteristic peaks are found around the values of 1744 and 1112 cm −1 , representing the stretching vibrations of C=O and C-O-C bonds, respectively. Since BG was deposited as a thin film together with VD3, the presence of Si-O-Si groups can also be observed [40,42]. However, from the point of view of the efficient transfer of the composite material and the preservation of chemical integrity, optimal results were revealed for the BG+VD3_025 samples.…”

Section: Surface Investigation Of As-deposited Thin Filmsmentioning

confidence: 99%

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Bioglass and Vitamin D3 Coatings for Titanium Implants: Osseointegration and Corrosion Protection

Negut,

Gradisteanu-Pircalabioru,

Dinu

et al. 2023

Biomedicines

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The use of MAPLE synthesized thin films based on BG and VD3 for improving the osseointegration and corrosion protection of Ti-like implant surfaces is reported. The distribution of chemical elements and functional groups was shown by FTIR spectrometry; the stoichiometry and chemical functional integrity of thin films after MAPLE deposition was preserved, optimal results being revealed especially for the BG+VD3_025 samples. The morphology and topography were examined by SEM and AFM, and revealed surfaces with many irregularities, favoring a good adhesion of cells. The thin films’ cytotoxicity and biocompatibility were evaluated in vitro at the morphological, biochemical, and molecular level. Following incubation with HDF cells, BG57+VD3_ 025 thin films showed the best degree of biocompatibility, as illustrated by the viability assay values. According to the LDH investigation, all tested samples had higher values compared to the unstimulated cells. The evaluation of cell morphology was performed by fluorescence microscopy following cultivation of HDF cells on the obtained thin films. The cultivation of HDF’s on the thin films did not induce major cellular changes. Cells cultured on the BG57+VD3_025 sample had similar morphology to that of unstimulated control cells. The inflammatory profile of human cells cultured on thin films obtained by MAPLE was analyzed by the ELISA technique. It was observed that the thin films did not change the pro- and anti-inflammatory profile of the HDF cells, the IL-6 and IL-10 levels being similar to those of the control sample. The wettability of the MAPLE thin films was investigated by the sessile drop method. A contact angle of 54.65° was measured for the sample coated with BG57+VD3_025. Electrochemical impedance spectroscopy gave a valuable insight into the electrochemical reactions occurring on the surface.

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Section: Surface Investigation Of As-deposited Thin Filmsmentioning

confidence: 96%

Section: Surface Investigation Of As-deposited Thin Filmsmentioning

confidence: 99%

Bioglass and Vitamin D3 Coatings for Titanium Implants: Osseointegration and Corrosion Protection

Negut,

Gradisteanu-Pircalabioru,

Dinu

et al. 2023

Biomedicines

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Sol–gel‑templated bioactive glass scaffold: a review

Shoushtari,

Hoey,

Biak

et al. 2024

Res. Biomed. Eng.

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Purpose This review paper explores diverse synthesis strategies within the sol–gel technique for producing silicate bioglass with a focus on tailoring these materials for bone scaffold design. Method A comprehensive search was conducted across various databases, including ScienceDirect, Taylor & Francis, PubMed, Hindawi, Royal Society of Chemistry (RSC), Wiley Online Library, ResearchGate, and Google Scholar, using keywords such as “silica bioglass,” “Sol–gel technique,” “Templating,” and “Bone scaffold.” The analysis considered variables such as the sol–gel method, the templating approach, and materials used to fabricate silica bioglass bone scaffolds. Out of 140 initially identified studies, 92 were selected for detailed review published within the last two decades. Result and conclusion In this study, the effect of the sol–gel fabrication technique on the improvement of the structure of silicate bioglass bone scaffolds has been reviewed, along with a consideration of the associated advantages and disadvantages. Specifically, the focus of this study was on the templating sol–gel method and its direct impact on morphology and pore structures. Consequently, these findings have evaluated the development of templating sol–gel fabrication techniques for enhancing the bioactivity and biocompatibility of bone scaffolds.

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Effect of magnetite nanoparticles on the biological and mechanical properties of hydroxyapatite porous scaffolds coated with ibuprofen drug

Sahmani

Khandan

Saber‐Samandari

et al. 2020

Materials Science and Engineering: C

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Effect of collagen type I and vitamin D3 functionalization of biomimetic bioglass scaffolds on hydroxyapatite condensation

Cited by 4 publications

References 17 publications

Bioglass and Vitamin D3 Coatings for Titanium Implants: Osseointegration and Corrosion Protection

Bioglass and Vitamin D3 Coatings for Titanium Implants: Osseointegration and Corrosion Protection

Sol–gel‑templated bioactive glass scaffold: a review

Effect of magnetite nanoparticles on the biological and mechanical properties of hydroxyapatite porous scaffolds coated with ibuprofen drug

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