Effect of ciprofloxacin antibiotic on the partial-nitritation process and bacterial community structure of a submerged biofilter

González‐Martínez, Alejandro; Rodríguez-Sánchez, Alejandro; Martı́nez-Toledo, M.V.; García-Ruiz, María Jesús; Hontoria, E.; Osorio-Robles, F.; González‐López, Jesús

doi:10.1016/j.scitotenv.2014.01.012

Cited by 94 publications

(54 citation statements)

References 54 publications

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“…Today, there are six examples of full-scale partial nitritation plants in The Netherlands and one in the USA [9]. 15 mg/L (10,000-100,000 population equivalent) 3 10 mg/L (more than 100,000 population equivalent) 3 …”

Section: Partial Nitritation Process: An Overviewmentioning

confidence: 99%

“…In this context, it has been reported that the partial nitritation process can be drastically inhibited by quinolone antibiotics, such as ciprofloxacin [76]. Quinolone antibiotics have been found in influent urban wastewater in concentrations ranging up to 426 ng/L [3].…”

Section: Effect Of Salinity Starvation Of Biomass and Emerging Contamentioning

confidence: 99%

“…Antibiotics, such as fluoroquinolones, have been reported [2,3] as able to impact the performance of the partial nitritation process, suggesting that there is a negative correlation between antibiotic concentration in the influent and performance of the partial nitritation process. Furthermore, the microbial community inside the bioreactors suffers a period of adaptation or a deep change with a significant reduction of the ammonium-oxidizing bacteria in response to the antibiotic concentration in the influent [3].…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, the microbial community inside the bioreactors suffers a period of adaptation or a deep change with a significant reduction of the ammonium-oxidizing bacteria in response to the antibiotic concentration in the influent [3]. Additionally, the presence of antibiotics in the bioreactor increases the number of antibiotic-resistant bacteria.…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, the presence of antibiotics in the bioreactor increases the number of antibiotic-resistant bacteria. In this way, it could be suggested that the presence of selected antibiotics, such as quinolones, can seriously affect partial nitritation systems and select microorganisms with antibiotic resistance [3].…”

Section: Introductionmentioning

confidence: 99%

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The Effect of Influent Characteristics and Operational Conditions over the Performance and Microbial Community Structure of Partial Nitritation Reactors

Rodríguez-Sánchez

González‐Martínez

Martı́nez-Toledo

et al. 2014

Water

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Nitrogen is a main contaminant of wastewater worldwide. Novel processes for nitrogen removal have been developed over the last several decades. One of these is the partial nitritation process. This process includes the oxidation of ammonium to nitrite without the generation of nitrate. The partial nitritation process has several advantages over traditional nitrification-denitrification processes for nitrogen removal from wastewaters. In addition, partial nitritation is required for anammox elimination of nitrogen from wastewater. Partial nitritation is affected by operational conditions and substances present in the influent, such as quinolone antibiotics. In this review, the impact that several operational conditions, such as temperature, pH, dissolved oxygen concentration, hydraulic retention time and solids retention time, have over the partial nitritation process is covered. The effect of quinolone antibiotics and other emerging contaminants are discussed. Finally, future perspectives for the partial nitritation process are commented upon.

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Section: Partial Nitritation Process: An Overviewmentioning

confidence: 99%

Section: Effect Of Salinity Starvation Of Biomass and Emerging Contamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

The Effect of Influent Characteristics and Operational Conditions over the Performance and Microbial Community Structure of Partial Nitritation Reactors

Rodríguez-Sánchez

González‐Martínez

Martı́nez-Toledo

et al. 2014

Water

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UPLC–MS/MS method validation of ciprofloxacin in human urine: Application to biodegradability study in microbial fuel cell

Sharma

Kumar

Mutnuri

2018

Biomedical Chromatography

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To enable the reliable quantification of ciprofloxacin in human urine, a sensitive and selective assay based on liquid chromatography-tandem mass spectrometry was developed. The chromatographic separation of the ciprofloxacin was carried out on a Zorbex Eclipse C 18 column using methanol and ammonium acetate as a mobile phase by the gradient elution method. The developed assay covered a wide range of concentrations (1.56-100 ng/mL) with a lower limit of detection of 0.76 ng/mL. Quantification was performed using the multiple reaction monitoring transitions 331.8/231 for ciprofloxacin and 362/318 for ofloxacin (internal standard). This assay was validated for linearity, accuracy, precision and recovery. The validated method was then applied to the biodegradability of ciprofloxacin (99%) from human urine in the microbial fuel cell.

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Bacterial community structure of a lab‐scale anammox membrane bioreactor

González‐Martínez

Osorio

Rodríguez-Sánchez

et al. 2014

Biotechnology Progress

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Autotrophic nitrogen removal technologies have proliferated through the last decade. Among these, a promising one is the membrane bioreactor (MBR) Anammox, which can achieve very high solids retention time and therefore sets a proper environment for the cultivation of anammox bacteria. In this sense, the MBR Anammox is an efficient technology for the treatment of effluents with low organic carbon and high ammonium concentrations once it has been treated under partial nitrification systems. A lab-scale MBR Anammox bioreactor has been built at the Technological University of Delft, The Netherlands and has been proven for efficient nitrogen removal and efficient cultivation of anammox bacteria. In this study, next-generation sequencing techniques have been used for the investigation of the bacterial communities of this MBR Anammox for the first time ever. A strong domination of Candidatus Brocadia bacterium and also the presence of a myriad of other microorganisms that have adapted to this environment were detected, suggesting that the MBR Anammox bioreactor might have a more complex microbial ecosystem that it has been thought. Among these, nitrate-reducing heterotrophs and primary producers, among others, were identified. Definition of the ecological roles of the OTUs identified through metagenomic analysis was discussed.

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Effect of ciprofloxacin antibiotic on the partial-nitritation process and bacterial community structure of a submerged biofilter

Cited by 94 publications

References 54 publications

The Effect of Influent Characteristics and Operational Conditions over the Performance and Microbial Community Structure of Partial Nitritation Reactors

The Effect of Influent Characteristics and Operational Conditions over the Performance and Microbial Community Structure of Partial Nitritation Reactors

UPLC–MS/MS method validation of ciprofloxacin in human urine: Application to biodegradability study in microbial fuel cell

Bacterial community structure of a lab‐scale anammox membrane bioreactor

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