Effect of chitosan reinforcement on properties of hydroxyapatite/silk fibroin composite for biomedical application

Mobika, J.; Rajkumar, M.; Priya, V. Nithya; Sibi, Srinath

doi:10.1016/j.physe.2021.114734

Cited by 10 publications

(7 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the first 24 h of degradation, the pH decreased from 7.4 to the range of 6.7-6.5, which may be due to the degradation of the residual amino or acetic acid group of the composite material, since the variations were close to a neutral pH, it can be concluded that the dressing will not have adverse damage to the host. 23…”

Section: Enzymatic Degradationmentioning

confidence: 99%

O-carboxymethyl chitosan/gelatin/silver-copper hydroxyapatite composite films with enhanced antibacterial and wound healing properties

et al. 2022

View full text Add to dashboard Cite

Wound dressing composite films of O-carboxymethyl chitosan (OCMC) and gelatin were prepared and mixed with hydroxyapatite (HA) composited with Silver (Ag) and Copper (Cu) at different concentrations. The chemical, thermal, morphological, and biological properties of the composite films were studied. The analysis by FTIR confirmed the presence of interactions between gelatin and OCMC, and at the same time, the polymer matrix interactions with Ag-Cu/HA complex. The inclusion of nanoparticle to the composite was associated with an improvement of the thermal stability, morphological roughness, a 9–12% more hydrophobic behavior (composite C1, C5, and C8), increase in antibacterial activity from 23.2 to 33.1% for gram negative bacteria and from 37.28 to 40.59% for gram positive bacteria, and with a cell viability greater than 100% for 24 and 72 h. The films obtained can serve as a wound healing dressing and regenerating biomaterial.

show abstract

Section: Enzymatic Degradationmentioning

confidence: 99%

O-carboxymethyl chitosan/gelatin/silver-copper hydroxyapatite composite films with enhanced antibacterial and wound healing properties

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Hydroxyapatite (HAp), Ca 10 (PO 4 ) 6 (OH) 2 is a bioceramic-based calcium phosphate compound that is stable under body fluids [ 1 ]. The crystal structure of HAp is hexagonal, having a molar ratio of a Ca/P of 1.67 [ 2 ], which is currently widely applied in biomedical fields such as orthopedics and dentistry, bone tissue engineering, drug delivery materials, and cell imaging [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…Polymers are large molecules formed by small and simple chemical units in the form of monomers. Therefore, polymers are often used, such as alginate [ 12 ], chitosan [ 13 ], cellulose [ 14 ], silk fibroin [ 1 ], PVA [ 15 ], and others. In this study, the polymer is alginate.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Alginate Concentration on Crystallinity, Morphology, and Thermal Stability Properties of Hydroxyapatite/Alginate Composite

et al. 2023

View full text Add to dashboard Cite

Hydroxyapatite (HAp) has been used for various applications such as orthopedics, drug delivery material, and bone tissue engineering. It is well known that HAp has a good biocompatibility and osteoconductivity, so HAp can be used in biomedical applications. Hydroxyapatite can be combined with other materials, in particular polymer, to expand its range of applications. In this study, the polymer that will be used as a support for the HAp composite is alginate (Alg). The HAp/Alg composite has been synthesized by the precipitation method. The XRD results show that the crystal system of HAp was hexagonal. The spheric-like shaped particles can be observed from SEM images, and particle size distribution spread from 400 to 1100 nm. The EDS spectrum exhibited the peak of Ca, C, P, and O elements, indicating that alginate had interacted with hydroxyapatite in the synthesized composite. The as-fabricated composite showed not only good crystallinity but also high thermal resistance. Thermogravimetric-differential thermal analysis (TGA-DTA) revealed that the HAp/Alg composites have a constant weight at 750 °C, so it might be applied in advanced applications such as bioimaging, drug carrier, and other cancer treatments.

show abstract

“…Carbon nanotubes and reduced graphene oxide display unique and exceptional properties such as high specific surface area, ultralightweight, high mechanical and tensile strengths, high electrical and thermal conductivity, oxygen-containing groups sites, and good thermal and chemical stability which are transferred to the matrix where they are combined, bringing additional properties [20]. The synergistic effect of nano-sized filler with polymeric matrices becomes suitable for enhancing biopolymers such as chitosan's electrical, optical, and mechanical properties [21][22][23][24][25][26][27][28][29][30][31][32][33]. Theoretical calculations have reported that chitosan promotes the dispersion of CNT in an aqueous solution by wrapping along the CNT axis [34][35][36].…”

Section: Introductionmentioning

confidence: 99%

Improved mechanical, optical, and electrical properties of chitosan films with the synergistic reinforcing effect of carbon nanotubes and reduced graphene oxide for potential optoelectronic applications

González-Martínez

Magallanes-Vallejo²,

López‐Oyama³

et al. 2023

Preprint

View full text Add to dashboard Cite

The purpose of this study was to determine the effects of carbon nanotubes (CNT), reduced graphene oxide (rGO), and a mixture of the (CNT-rGO) on the structural, mechanical, electrical, and optical properties of low (CSL), medium (MCS) and high-molecular (HCS) weight chitosan. The formed films' structure and physical properties were analyzed using swelling, X-ray diffraction, mechanical testing, and SEM micrographs. The 4-Probe technique showed that chitosan electrical conductivity was improved by six orders of magnitude strongly influenced by the CNT addition. The photoluminescence (PL) studies showed that rGO addition induces a non-radiative process in composites and decreases the PL intensity by nearly 43%. The CNTs in CSL and the mixture in CSL present the best electrical, optical, and swelling degree properties. The composites properties and ease of preparation of the films reported in this work make them suitable for optoelectronic applications due to their electrical conductivity and PL values.

show abstract

Effect of chitosan reinforcement on properties of hydroxyapatite/silk fibroin composite for biomedical application

Cited by 10 publications

References 46 publications

O-carboxymethyl chitosan/gelatin/silver-copper hydroxyapatite composite films with enhanced antibacterial and wound healing properties

O-carboxymethyl chitosan/gelatin/silver-copper hydroxyapatite composite films with enhanced antibacterial and wound healing properties

The Effect of Alginate Concentration on Crystallinity, Morphology, and Thermal Stability Properties of Hydroxyapatite/Alginate Composite

Improved mechanical, optical, and electrical properties of chitosan films with the synergistic reinforcing effect of carbon nanotubes and reduced graphene oxide for potential optoelectronic applications

Contact Info

Product

Resources

About