Effect of Carduus marrianus and Chelidonium majus in hepatic damage

Abstract

The present study was undertaken to investigate hepatoprotective activity of Carduus marrianus and Chelidonium majus against paracetamol intoxicated rats and supplemented by histopathological studies of liver tissues. The Homoeopathic Potencies of C. marianus and C. majus have significantly altered the Paracetamol induced liver damages. Hepatic collagen content as evident from decreased (p<0.05) hydroxyproline levels and hepatic mast cell infiltration were significantly decreased in pre-treated animals. In addition, C. marianus and C. majus potencies significantly (p<0.05) reduced hepatic lipid peroxidation as evident in the liver tissues. The findings of study suggested that potencies of C. marianus and C. Majus heal the Paracetamol induced Hepatic tissue damages. Hence it is have more potential effect in hepatoprotective activity.

Action of Carduus marianus 6cH on Hepatopathy and Gallstone in Ambystoma mexicanum (Axolotl): Case Report

“…It was concluded that there were no toxic effects from any of the different potencies used and, moreover, that C. marianus exerted a hepatoprotective effect superior to the widely used drug silymarin. 16 In 10 Magellanic penguins, use of C. marianus 6cH, once a day for 30 days, resulted in mean reductions in serum aspartate aminotransferase and alanine aminotransferase without side effects. It was also found that this agent was easily administered.…”