Effect of Blue Light on Acne Vulgaris: A Systematic Review

Diogo, Mara Lúcia Gonçalves; Campos, Thalita Molinos; Fonseca, Elsa; Pavani, Christiane; Horliana, Anna Carolina Ratto Tempestini; Fernandes, Kristianne Porta Santos; Bussadori, Sandra Kalil; Fantin, Francisca Goreth Malheiro Moraes; Leite, Diego Portes Vieira; Araki, Ângela Toshie; Navarro, Ricardo Scarparo; Motta, Lara Jansiski

doi:10.3390/s21206943

Cited by 25 publications

(25 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The blue light therapy is suitable for treating acne and killing bacteria on the skin layer. Sadowska et al [5], Diogo et al [6], and Opel et al [7] stated a large number of documented reviews related to the use of blue LEDs phototherapy and they confirmed the conclusive findings that the light from blue LEDs (405-420 nm) was effective in mild to moderate inflammatory of the face treatment of the acne vulgaris and P.acne. In addition, some data [6], [7] indicated that light from the blue LEDs (400-470 nm) may also help treat the acne and P.acne.…”

Section: Introductionmentioning

confidence: 84%

“…These parameters should include at least the type of light source, wavelength, optical power, energy, radiation exposure (J/cm 2 ) irradiation or power density (W/m or mW/cm 2 ) and the mode of use of the device (wearable, portable or distance). In this paper, the design goal was set as a power density of red light of 1 0mW/cm 2 and blue light of 20 mW/cm 2 , which was a light intensity suitable for LLLT phototherapy [5], [6], [17], [21] . The authors focused on selecting the LED spectrum to meet the research objectives.…”

Section: -In-1 Led Array Modulementioning

confidence: 99%

See 1 more Smart Citation

Design and realization of a dual-wavelength low level light therapy for acne and face rejuvenation treatment

Watjanatepin

Kiatsookkanatorn

Boonmee

et al. 2022

IJEECS

View full text Add to dashboard Cite

Low-level light therapy (LLLT) uses the light of wavelength between 400–700 nm to treat acne, reduce inflammation, stimulate collagen production, and rejuvenate the facial skin. This study designed and constructed a dual-wavelength LED LLLT device for the facial treatment. The light spectrum, power density, uniformity, stability, and safety of the device were analyzed. The proposed system consisted of an LED array with 415 and 633 nm wavelengths. Human machine interface with embedded system was used to control light intensity and treatment time. The phototherapy device is designed to be curvaceously sized to suit the face shape of Asian people. The results showed that the LLLT device emitted 633±5 nm red and 415±5 nm blue light with a linear adjustable light power density of 0-18.56 mW/cm2 and 0-3.70 mW/cm2, respectively. The spectrum distribution of the red and blue light was relatively constant over 30 minutes of operation. The uniformity and stability of red spectrum were about 89.9% and 95.08% and blue spectrum were 87.6% and 97.08%, respectively. The experimental face’s temperature was below 31.5 . For the future study, the LED phototherapy device will be applied for clinical research in collaboration with dermatologists.Low-level light therapy (LLLT) uses the light of wavelength between 400–700 nm to treat acne, reduce inflammation, stimulate collagen production, and rejuvenate the facial skin. This study designed and constructed a dual-wavelength LED LLLT device for the facial treatment. The light spectrum, power density, uniformity, stability, and safety of the device were analyzed. The proposed system consisted of an LED array with 415 and 633 nm wavelengths. Human machine interface with embedded system was used to control light intensity and treatment time. The phototherapy device is designed to be curvaceously sized to suit the face shape of Asian people. The results showed that the LLLT device emitted 633±5 nm red and 415±5 nm blue light with a linear adjustable light power density of 0-18.56 mW/cm2 and 0-3.70 mW/cm2, respectively. The spectrum distribution of the red and blue light was relatively constant over 30 minutes of operation. The uniformity and stability of red spectrum were about 89.9% and 95.08% and blue spectrum were 87.6% and 97.08%, respectively. The experimental face’s temperature was below 31.5 . For the future study, the LED phototherapy device will be applied for clinical research in collaboration with dermatologists.

show abstract

Section: Introductionmentioning

confidence: 84%

Section: -In-1 Led Array Modulementioning

confidence: 99%

Design and realization of a dual-wavelength low level light therapy for acne and face rejuvenation treatment

Watjanatepin

Kiatsookkanatorn

Boonmee

et al. 2022

IJEECS

View full text Add to dashboard Cite

show abstract

“…The mice were anesthetized using 2% isoflurane (MSD Animal Health, Kenilworth, NJ, USA); the mice were placed in the supine position, and the abdomen was irradiated using a blue laser (100 or 30 mW/cm 2 for 20 min). The irradiation conditions were based on those used in clinical practice for PBM using blue light [ 20 , 21 ]. Skin tissues (5 × 5 mm) were collected immediately after irradiation.…”

Section: Methodsmentioning

confidence: 99%

Blue Laser Irradiation Decreases the ATP Level in Mouse Skin and Increases the Production of Superoxide Anion and Hypochlorous Acid in Mouse Fibroblasts

Nakayama

Kubota

Mayumi

et al. 2022

Biology

View full text Add to dashboard Cite

Photobiomodulation studies have reported that blue light irradiation induces the production of reactive oxygen species. We investigated the effect of blue laser (405 nm) irradiation on the ATP levels in mouse skin and determined the types of reactive oxygen species and reactive nitrogen species using cultured mouse fibroblasts. Blue laser irradiation caused a decrease in the ATP level in the mouse skin and triggered the generation of superoxide anion and hypochlorous acid, whereas nitric oxide and peroxynitrite were not detected. Moreover, blue laser irradiation resulted in reduced cell viability. It is believed that the decrease in the skin ATP level due to blue light irradiation results from the increased levels of oxidative stress due to the generation of reactive oxygen species. This method of systematically measuring the levels of reactive oxygen species and reactive nitrogen species may be useful for understanding the effects of irradiation conditions.

show abstract

“…Therefore, light signals are converted into intracellular signals through OPN in human skin photoreception, and this new phototransduction mechanism is of vital importance for understanding photobiomodulation (PBM) therapy, a form of local light therapy based on non-ionizing light sources. Clinically, PBM therapy is becoming a promising treatment for a variety of skin conditions, such as hair regeneration, wound healing, psoriasis, eczema, and atopic dermatitis [135][136][137][138][139]. Future studies focusing on elucidating the underlying mechanisms of different opsins to regulate skin physiological processes, and defining the corresponding light parameters to optimize light therapy will expand clinical indications for PBM and change the treatment landscape for more skin diseases.…”

Section: Phototransductionmentioning

confidence: 99%

Recognition of Melanocytes in Immuno-Neuroendocrinology and Circadian Rhythms: Beyond the Conventional Melanin Synthesis

Chen

Liu

Zhou

et al. 2022

Cells

View full text Add to dashboard Cite

Melanocytes produce melanin to protect the skin from UV-B radiation. Notwithstanding, the spectrum of their functions extends far beyond their well-known role as melanin production factories. Melanocytes have been considered as sensory and computational cells. The neurotransmitters, neuropeptides, and other hormones produced by melanocytes make them part of the skin’s well-orchestrated and complex neuroendocrine network, counteracting environmental stressors. Melanocytes can also actively mediate the epidermal immune response. Melanocytes are equipped with ectopic sensory systems similar to the eye and nose and can sense light and odor. The ubiquitous inner circadian rhythm controls the body’s basic physiological processes. Light not only affects skin photoaging, but also regulates inner circadian rhythms and communicates with the local neuroendocrine system. Do melanocytes “see” light and play a unique role in photoentrainment of the local circadian clock system? Why, then, are melanocytes responsible for so many mysterious functions? Do these complex functional devices work to maintain homeostasis locally and throughout the body? In addition, melanocytes have also been shown to be localized in internal sites such as the inner ear, brain, and heart, locations not stimulated by sunlight. Thus, what can the observation of extracutaneous melanocytes tell us about the “secret identity” of melanocytes? While the answers to some of these intriguing questions remain to be discovered, here we summarize and weave a thread around available data to explore the established and potential roles of melanocytes in the biological communication of skin and systemic homeostasis, and elaborate on important open issues and propose ways forward.

show abstract

Effect of Blue Light on Acne Vulgaris: A Systematic Review

Cited by 25 publications

References 39 publications

Design and realization of a dual-wavelength low level light therapy for acne and face rejuvenation treatment

Design and realization of a dual-wavelength low level light therapy for acne and face rejuvenation treatment

Blue Laser Irradiation Decreases the ATP Level in Mouse Skin and Increases the Production of Superoxide Anion and Hypochlorous Acid in Mouse Fibroblasts

Recognition of Melanocytes in Immuno-Neuroendocrinology and Circadian Rhythms: Beyond the Conventional Melanin Synthesis

Contact Info

Product

Resources

About