Effect of amelogenin ECM protein on the healing of chronic leg ulcers with atrophie blanche

Fogh, Karsten; Nielsen, Charles; W, Dam

doi:10.12968/jowc.2012.21.12.612

Cited by 4 publications

(1 citation statement)

References 4 publications

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“…High protein diets may improve the healing of pressure ulcer. A number of studies have demonstrated that high protein intake is beneficial for pressure ulcer healing ( 8 , 10 , 11 ). In addition, many animal pressure ulcer models have been developed to test the effect of protein in this field ( 12 , 13 ).…”

Section: Introductionmentioning

confidence: 99%

Pressure ulcer healing promoted by adequate protein intake in rats

et al. 2018

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The effect of protein intake on rat pressure ulcer healing was evaluated. One hundred rats were numbered according to body weight and then they were randomly divided into 4 groups (n=25) using the random number table. After rat models of stage II pressure ulcer were established, they were fed with feed containing different protein levels (10, 15, 20 and 25%). Healing time, pressure ulcer area, body weight, albumin (ALB) and hemoglobin (Hb) levels among groups were compared. Hematoxylin and eosin (H&E) staining was also performed to observe pressure ulcer tissue structure. In the healing process of pressure ulcer, rats with 20% protein intake had the shortest healing time and the smallest pressure ulcer area. Body weight, ALB and Hb levels were much closer to the normal level. H&E staining result also suggested that the pressure ulcer healing degree of rats with 20% protein intake was much better than the others. Adequate protein intake is therefore conducive to pressure ulcer healing, while excessive or insufficient protein intake has negative impact on healing.

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Section: Introductionmentioning

confidence: 99%

Pressure ulcer healing promoted by adequate protein intake in rats

et al. 2018

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Use of Collagen Extracellular Matrix Dressing for the Treatment of a Recurrent Venous Ulcer in a 52-Year-Old Patient

Gonzalez

2016

Journal of Wound, Ostomy &Amp; Continence Nursing

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The initial venous leg ulcer in this patient required 10 weeks to achieve closure. Ninety-eight percent resolution of the recurrent ulcer had occurred within 4 weeks of treatment, with complete closure at 7 weeks. The average healing time for recurrent venous ulcers is reported in the literature to be longer than initial venous ulcers. In the case provided, collagen ECM dressings promoted complete wound healing in 49 days.

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Effectiveness of extracellular matrix dressings and topical agents in the treatment of leg ulcers: a systematic review protocol

Petz

Meier

Roehrs

et al. 2018

JBI Database of Systematic Reviews and Implementation Reports

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Effect of amelogenin ECM protein on the healing of chronic leg ulcers with atrophie blanche

Abstract: The results of this retrospective study suggest that AEMP improves healing in chronic venous leg ulcers combined with atrophie blanche.

Cited by 4 publications

References 4 publications

Pressure ulcer healing promoted by adequate protein intake in rats

Pressure ulcer healing promoted by adequate protein intake in rats

Use of Collagen Extracellular Matrix Dressing for the Treatment of a Recurrent Venous Ulcer in a 52-Year-Old Patient

Effectiveness of extracellular matrix dressings and topical agents in the treatment of leg ulcers: a systematic review protocol

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