Effect of aging on various haematological parameters

Padalia, Maulik; Trivedi, Radhe Shyam; Panchal, Preeti; Jani, Hitesh A.

doi:10.7439/ijbar.v5i10.901

Cited by 2 publications

(3 citation statements)

References 3 publications

(3 reference statements)

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“…The results of white blood cell and platelets in this study had some similarity with another study that showed the effect of oral contraceptive pills on haematological indices [24]. Furthermore, haemoglobin, red blood cell count and packed cell volume of individual within the age grade of 20 -89 do not significantly vary in male but significantly varies in females [22]. This could be due to the changes in body physiology among females probably due to mensuration, pregnancy and menopause conditions.…”

Section: Resultssupporting

confidence: 83%

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Evaluation of Some Haematological Parameters Among Post-menopausal Women in Bayelsa State, Nigeria: A Case Study of Patients Attending Federal Medical Centre, Yenagoa

Eledo¹

2017

AJLM

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This study evaluated some haematological parameters among post-menopausal women in Yenagoa, Bayelsa state, Nigeria. Sixty two post-menopausal women within the age of 52 -70 and forty adult females within the age of 18 -32 participated in this study. About 5ml of blood was collected from each participant and analyzed using Westergren method for erythrocyte sedimentation rate (ESR) and automated haematology analyser (System XS-1000i) for packed cell volume (PCV), haemoglobin (Hb), total white cell count (WBC), platelet count (PLT) and differential viz: lymphocytes, neutrophil, monocytes, eosinophils and basophils. Results showed that the test (post-menopausal women) and control subject had 12.21±1.00 g/dl and 13.22±0.71 g/dl respectively (Hb), 36.60±3.00% and 39.70±2.22% respectively (PCV), 5.24±0.63×10 9 /L and 7.23±1.04×10 9 /L respectively (WBC), 174.63±27.46×10 9 /L and 260.20±45.54×10 9 /L respectively (PLT) and 43.02±6.77 mm/hour and 8.08±2.68 mm/hour respectively (ESR). Statistically, there was a significant (P<0.05) reduction in PLT, PCV, Hb and monocytes, and significant increase in ESR and neutrophil among the post-menopausal women when compared to the control. Other blood differential such as lymphocytes, eosinophils and basophils were not affected by menopause. This suggests that post-menopausal changes alter some haematological parameters, which may predispose the women to infections.

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Section: Resultssupporting

confidence: 83%

“…Furthermore, it could also be due to nutritional/dietary intake of some nutrients, environmental and or genetic makeup. Poor nutrition resulting in vitamin B12 and folic acid deficiency in old age could cause early haematological changes during ageing [22].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Some Haematological Parameters Among Post-menopausal Women in Bayelsa State, Nigeria: A Case Study of Patients Attending Federal Medical Centre, Yenagoa

Eledo¹

2017

AJLM

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“…Authors have reported that nutrition could also affect some haematological parameters. For instance, Padalia et al [39] reported that poor nutrition resulted in vitamin B12 and folic acid deficiency; in old age this could cause haematological changes. This reduction in total white blood cell and CD4 cells could be due to the effect of ageing.…”

Section: Resultsmentioning

confidence: 99%

Evaluation of Total White Blood Cells and Cluster of Differentiation 4 Cells among Post-Menopausal Women in Elele, Nigeria

Eledo¹,

Igwe²,

Izah³

2018

MRI

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This study investigated some immune system related parameters among post-menopausal women in Elele, River state, Nigeria. Forty-two individuals participated in this study and forty control subjects were established as well. Blood was collected from the participants, and CD4 cells and total white blood cells count were analyzed using standard procedures. Result showed that test subjects and control values were 5.46 ± 1.64 × 10 9 /L and 7.24 ± 1.47 × 10 9 /L, respectively for total white blood cell and 1265.19 ± 458.56 cells/µl and 2159.53 ± 400.02 cells/µl respectively, for CD4 cells. There was significant difference (P < 0.001) among the test subject and control for both parameters. The results in the test subjects for both parameters were significantly lower compared to the control. The decline in immune system related parameters among the test subjects may predispose them at risk of multiple infections and other associated health conditions.

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Effect of aging on various haematological parameters

Cited by 2 publications

References 3 publications

Evaluation of Some Haematological Parameters Among Post-menopausal Women in Bayelsa State, Nigeria: A Case Study of Patients Attending Federal Medical Centre, Yenagoa

Evaluation of Some Haematological Parameters Among Post-menopausal Women in Bayelsa State, Nigeria: A Case Study of Patients Attending Federal Medical Centre, Yenagoa

Evaluation of Total White Blood Cells and Cluster of Differentiation 4 Cells among Post-Menopausal Women in Elele, Nigeria

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