Evaluation of Some Haematological Parameters Among Post-menopausal Women in Bayelsa State, Nigeria: A Case Study of Patients Attending Federal Medical Centre, Yenagoa

Abstract

This study evaluated some haematological parameters among post-menopausal women in Yenagoa, Bayelsa state, Nigeria. Sixty two post-menopausal women within the age of 52 -70 and forty adult females within the age of 18 -32 participated in this study. About 5ml of blood was collected from each participant and analyzed using Westergren method for erythrocyte sedimentation rate (ESR) and automated haematology analyser (System XS-1000i) for packed cell volume (PCV), haemoglobin (Hb), total white cell count (WBC), platelet count (PLT) and differential viz: lymphocytes, neutrophil, monocytes, eosinophils and basophils. Results showed that the test (post-menopausal women) and control subject had 12.21±1.00 g/dl and 13.22±0.71 g/dl respectively (Hb), 36.60±3.00% and 39.70±2.22% respectively (PCV), 5.24±0.63×10 9 /L and 7.23±1.04×10 9 /L respectively (WBC), 174.63±27.46×10 9 /L and 260.20±45.54×10 9 /L respectively (PLT) and 43.02±6.77 mm/hour and 8.08±2.68 mm/hour respectively (ESR). Statistically, there was a significant (P<0.05) reduction in PLT, PCV, Hb and monocytes, and significant increase in ESR and neutrophil among the post-menopausal women when compared to the control. Other blood differential such as lymphocytes, eosinophils and basophils were not affected by menopause. This suggests that post-menopausal changes alter some haematological parameters, which may predispose the women to infections.