Effect of acupuncture on aromatase inhibitor-induced arthralgia in patients with breast cancer: A meta-analysis of randomized controlled trials

Chen, Lawrence R.; Lin, Chao Chun; Huang, Tsai-Wei; Kuan, Yi Chun; Huang, Yao; Chen, Hung-Chou; Kao, Chun Yu; Su, Chih-Ming; Tam, Ka Wai

doi:10.1016/j.breast.2017.03.015

Cited by 49 publications

(30 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…182 A metaanalysis of five trials suggested a possible role for acupuncture in the management of AIA. 183 Conducting high-quality studies that include inert controls or sham interventions prove methodologically challenging. 184 Acupuncture potentially represents a useful component of a multi-modal approach to improving the quality of life in cancer survivors and is popular with patients.…”

Section: Acupuncturementioning

confidence: 99%

Pain in cancer survivors; filling in the gaps

Brown

Farquhar-Smith

2017

British Journal of Anaesthesia

View full text Add to dashboard Cite

Cancer survivorship represents a growing clinical challenge for pain clinicians. The population of cancer survivors is rapidly expanding and many of these patients experience pain as a sequelae of their disease and its treatment. The features, pathophysiology and natural history of some painful conditions observed in cancer survivors, such as direct tumour effects, cancer induced bone pain (CIBP) or chronic post-surgical pain have received extensive exposure elsewhere in the literature. In this narrative review, we attempt to 'fill in the gaps' in the knowledge, by providing a succinct outline of a range of less well known pain states encountered in the cancer survivor population. These include neuropathies as a result of graft versus host disease (GVHD), novel chemotherapeutic agents and monoclonal antibodies (mAb), and radiation induced pain states. The increasing prevalence of visceral post-surgical pain and aromatase inhibitor-induced arthralgia (AIA) is also detailed. Additionally an overview of suggested approaches to the assessment of pain in cancer survivors is provided and potential treatment strategies, with a focus on novel approaches are discussed.

show abstract

Section: Acupuncturementioning

confidence: 99%

Pain in cancer survivors; filling in the gaps

Brown

Farquhar-Smith

2017

British Journal of Anaesthesia

View full text Add to dashboard Cite

show abstract

“…Previously, several reviews have been published, focusing on the various types of interventions that target specific symptoms associated with adjuvant endocrine therapy [18][19][20][21][22]. To the best of our knowledge, a systematic review that examines the effectiveness of the different types of interventions on various known adjuvant endocrine therapy-induced symptoms, overall QOL and functional ability of patients is yet to be conducted.…”

Section: Introductionmentioning

confidence: 99%

The Effects of Pharmacological and Non-Pharmacological Interventions on Symptom Management and Quality of Life among Breast Cancer Survivors Undergoing Adjuvant Endocrine Therapy: A Systematic Review

Chan

Tai

Kwong

et al. 2020

IJERPH

View full text Add to dashboard Cite

Breast cancer survivors need to undergo adjuvant endocrine therapy after completion of curative treatments to prevent disease recurrence. These individuals often experience symptoms which are detrimental to their quality of life (QOL). Implementation of interventions for effective symptom management among these survivors is warranted. This review provides an overview of studies on the effectiveness of the previously developed interventions for breast cancer survivors undergoing adjuvant endocrine therapy on symptom alleviation and enhancement of QOL or health-related QOL (HRQOL). Five electronic databases were employed in the literature search. Study selection, data extraction and critical appraisal of the included studies were conducted by three authors independently. Twenty-four studies were included. Both pharmacological and non-pharmacological interventions are effective in addressing the symptoms associated with adjuvant endocrine therapy among the breast cancer survivors, and in improving their QOL, although discrepancies were noted between the studies in terms of the significance of these effects. Pharmacological and non-pharmacological interventions can be effective for symptom management among breast cancer survivors. Their implementation is recommended for effective survivorship care for these individuals. Further research on intervention development for breast cancer survivors is recommended to provide further evidence for the utility of the explored interventions in survivorship care for these patients.

show abstract

“…Providing patients with additional information material does not appear to affect compliance and persistence with anastrozole [23]. Although yoga has been reported to significantly improve musculoskeletal symptoms in various trials [17,19,24,25], there are contradictory results in relation to physical activity [18,19,26,27]; and the same applies to acupuncture [19,20,28,29] and other complementary and alternative medicines (CAM) [19,30,31].…”

Section: Introductionmentioning

confidence: 99%

Complementary and alternative medicine and musculoskeletal pain in the first year of adjuvant aromatase inhibitor treatment in early breast cancer patients

et al. 2020

View full text Add to dashboard Cite

a b s t r a c tBackground: Patients with breast cancer (BC) show strong interest in complementary and alternative medicine (CAM), particularly for adverse effects of adjuvant endocrine treatment d e.g., with letrozole. Letrozole often induces myalgia/limb pain and arthralgia, with potential noncompliance and treatment termination. This analysis investigated whether CAM before aromatase inhibitor (AI) therapy is associated with pain development and the intensity of AI-induced musculoskeletal syndrome (AIMSS) during the first year of treatment. Patients and methods: The multicenter phase IV PreFace study evaluated letrozole therapy in postmenopausal, hormone receptorepositive patients with early BC. Patients were asked about CAM use before, 6 months after, and 12 months after treatment started. They recorded pain every month for 1 year in a diary including questions about pain and numeric pain rating scales. Data were analyzed for patients who provided pain information for all time points. Results: Of 1396 patients included, 901 (64.5%) had used CAM before AI treatment. Throughout the observation period, patients with CAM before AI treatment had higher pain values, for both myalgia/limb pain and arthralgia, than non-users. Pain increased significantly in both groups over time, with the largest increase during the first 6 months. No significant difference of pain increase was noted regarding CAM use. Conclusions: CAM use does not prevent or improve the development of AIMSS. Pain intensity was generally greater in the CAM group. Therefore, because of the risk of non-compliance and treatment discontinuation due to the development of higher pain levels, special attention must be paid to patient education and aftercare in these patients.

show abstract

Effect of acupuncture on aromatase inhibitor-induced arthralgia in patients with breast cancer: A meta-analysis of randomized controlled trials

Cited by 49 publications

References 21 publications

Pain in cancer survivors; filling in the gaps

Pain in cancer survivors; filling in the gaps

The Effects of Pharmacological and Non-Pharmacological Interventions on Symptom Management and Quality of Life among Breast Cancer Survivors Undergoing Adjuvant Endocrine Therapy: A Systematic Review

Complementary and alternative medicine and musculoskeletal pain in the first year of adjuvant aromatase inhibitor treatment in early breast cancer patients

Contact Info

Product

Resources

About