Effect of a tart cherry juice blend on exercise-induced muscle damage in horses

Ducharme, N. G.; Fortier, Lisa A.; Kraus, Marc S.; Hobo, Seiji; Mohammed, Hussni O.; McHugh, Malachy P.; Hackett, Richard P.; Soderholm, L. V.; Mitchell, Lisa M.

doi:10.2460/ajvr.70.6.758

Cited by 30 publications

(31 citation statements)

References 47 publications

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“…For the purpose of statistical analysis, all samples with a result below the limit of detection were assigned a value of 20 pg/ml. Thiobarbituric acid reactive substances (TBARS) were measured fluorometrically using a commercial kit previously validated in the horse (Ducharme et al . 2009) 3 .…”

Section: Methodsmentioning

confidence: 99%

Neuroendocrine and non‐neuroendocrine markers of inflammation associated with performance in endurance horses

Holbrook¹,

McFarlane

Schott

2010

Equine Veterinary Journal

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SummaryReasons for performing study: The inflammatory and neuroendocrine response to endurance exercise and relationship of these parameters to performance is not well documented in horses. Hypotheses or objectives: Evidence of systemic inflammation is associated with poor performance in horses competing in endurance events. Methods: Blood was collected prior to and at the finish or elimination point from horses competing in both the 80 and 160 km American Endurance Ride National Championship competitions in 2006. Immunoreactive alphamelanocyte stimulating hormone (a-MSH) and tumour necrosis factor-alpha (TNF-a) were quantified utilising radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) techniques, respectively. The concentration of total thiobarbituric acid reactive substances (TBARS) was measured fluorometrically. Results: Thirty horses were included in the study. Endurance exercise was associated with a significant increase in TBARS in the 80 km group but not the 160 km group. TNF-a and a-MSH did not significantly change as a result of exercise in either distance group. Precompetition TBARS was significantly higher in horses that failed to finish the 80 km race, as well as when distances were combined. In addition, precompetition a-MSH was significantly lower in nonfinishers in the 160 km group. Furthermore, competition speed was positively correlated with precompetition a-MSH in the 80 km and negatively correlated with precompetition TNF-a when distances were combined. Conclusions: Our results suggest that basal oxidative stress markers, circulating cytokines and anti-inflammatory neuroendocrine hormones appear to correlate with endurance performance in horses. Potential relevance: Basal oxidative stress markers, circulating cytokines and anti-inflammatory neuroendocrine hormones may be predictive of athletic performance in endurance horses. Future studies evaluating the effect of training on these markers in endurance horses are warranted.

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Section: Methodsmentioning

confidence: 99%

Neuroendocrine and non‐neuroendocrine markers of inflammation associated with performance in endurance horses

Holbrook¹,

McFarlane

Schott

2010

Equine Veterinary Journal

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“…Besides concerns regarding the possibility that excessive use of NSAIDS may contribute to race-related injuries [33], long-term use of NSAIDs is associated with other adverse effects [35]. Thus, there is growing interest in nonpharmacologic approaches to ameliorate exercise-induced inflammation [36][37][38][39]. Various dietary supplements have been proposed to alleviate exercise-related injuries and illnesses [40][41][42][43][44][45][46][47][48][49][50].…”

Section: Introductionmentioning

confidence: 98%

The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training

Horohov

Sinatra

Chopra

et al. 2012

Journal of Equine Veterinary Science

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“…Thus, measuring the serum SAA concentration before entering a competition may indicate whether the horse is in poor condition, including subclinical disorders, overtraining or slight injuries that may worsen with exertion and lead to elimination from the ride [25]. Other authors have reported an increase in SAA concentration after moderate treadmill exercise during an experimental study on the effect of an antioxidative compound on exercise-induced muscle damage [27]. This observation is in agreement with Liburt’s et al findings that the level of proinflammatory and acute phase-related cytokines, including IL-1, TNF-α and IL-6 (in the muscles), increased after an incremental exercise test in unfit Standardbreds [28].…”

Section: Introductionmentioning

confidence: 99%

Serum amyloid A (SAA) concentration after training sessions in Arabian race and endurance horses

et al. 2013

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BackgroundSerum amyloid A (SAA) is the major acute phase protein in horses. Its concentration increases in various pathologies but also in response to prolonged, strenuous effort. The purpose of this study was to establish whether routine race and endurance training produces changes in the SAA level in Arabian horses. Additionally, the differences between SAA response in experienced endurance horses and endurance horses that were beginning their career were investigated.ResultsThere were no changes in SAA concentrations after race training and endurance training in experienced horses. In horses that were beginning their endurance training, exercise produced an increase in SAA level as compared with rest level.ConclusionIn Arabians, the SAA concentration seems to be a good indicator of endurance training but is useless in race training. The routine training of experienced horses, which were prepared for long distance rides, did not promote any changes in the SAA level. In contrast, a significant increase in the SAA concentration was observed in horses that were beginning their endurance training and were only prepared for moderate distance rides and underwent the same effort. Further research is needed to elucidate whether this difference reflects too heavy training or adaptation to an increasing workload. Additionally, the adaptation to long distance rides in Arabians may include a reduced acute phase response.

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Effect of a tart cherry juice blend on exercise-induced muscle damage in horses

Abstract: Administration of TCJB may diminish muscle damage induced by exercise.

Cited by 30 publications

References 47 publications

Neuroendocrine and non‐neuroendocrine markers of inflammation associated with performance in endurance horses

Neuroendocrine and non‐neuroendocrine markers of inflammation associated with performance in endurance horses

The Effect of Exercise and Nutritional Supplementation on Proinflammatory Cytokine Expression in Young Racehorses During Training

Serum amyloid A (SAA) concentration after training sessions in Arabian race and endurance horses

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