Effect of a probiotic multivitamin compound on stress and exhaustion

Gruenwald, Joerg; Graubaum, Hans‐Joachim; Harde, Andrea

doi:10.1007/bf02850270

Cited by 33 publications

(23 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Oral supplementation with B. brevi and L. casei reduced the occurrence of NEC in premature infants [103]; this was likely due to the improvement in gastrointestinal motility. Administration of a probiotic multivitamin preparation was also found to significantly reduce the stress or exhaustion symptoms in healthy subjects [104]. Another major gastrointestinal disease targeted to test probiotic application is irritable bowel syndrome (IBS).…”

Section: Discussionmentioning

confidence: 99%

Protection and Restitution of Gut Barrier by Probiotics: Nutritional and Clinical Implications

Rao¹,

Samak²

2013

CNF

199

View full text Add to dashboard Cite

Probiotics are beneficial bacteria present in various dietary components and many of these colonize in the human and animal intestine. In the gut probiotics help the host by assisting in maintenance of normal mucosal homeostasis. Probiotics not only help maintain normal function of the gut mucosa, but also protect mucosa from injurious factors such as toxins, allergens and pathogens. The beneficial effect of probiotics is mediated by multiple mechanisms, including cytoprotection, cell proliferation, cell migration, resistance to apoptosis, synthesis of proteins and gene expression. One of the important cytoprotective effects of probiotics in the intestinal mucosa is to strengthen the epithelial tight junctions and preservation of mucosal barrier function. Probiotics not only enhance barrier function by inducing synthesis and assembly of tight junction proteins, but also preventing disruption of tight junctions by injurious factors. Bioactive factors released by probiotics trigger activation of various cell signaling pathways that lead to strengthening of tight junctions and the barrier function. This article reviews and summarizes the current understanding of various probiotics that are involved in the protection of gut barrier function, highlights the cellular and molecular mechanisms involved in the protective effect and addresses the clinical implications of probiotic supplementation.

show abstract

Section: Discussionmentioning

confidence: 99%

Protection and Restitution of Gut Barrier by Probiotics: Nutritional and Clinical Implications

Rao¹,

Samak²

2013

CNF

199

View full text Add to dashboard Cite

show abstract

“…In another study, a combination of probiotic cultures and multivitamin/minerals has been shown to improve depressive symptoms in a group of fatigued adults under stress [148]. Chronic fatigue syndrome patients treated with Lactobacillus casei strain “Shirota” for two months showed a significant rise in both Lactobacillus and Bifidobacteria resulting in improved patient outcome [149].…”

Section: Future Emerging Areas For Probiotic Researchmentioning

confidence: 99%

Probiotics, Prebiotics, and Synbiotics: Gut and Beyond

Vyas

Ranganathan

2012

Gastroenterology Research and Practice

191

130

View full text Add to dashboard Cite

The human intestinal tract has been colonized by thousands of species of bacteria during the coevolution of man and microbes. Gut-borne microbes outnumber the total number of body tissue cells by a factor of ten. Recent metagenomic analysis of the human gut microbiota has revealed the presence of some 3.3 million genes, as compared to the mere 23 thousand genes present in the cells of the tissues in the entire human body. Evidence for various beneficial roles of the intestinal microbiota in human health and disease is expanding rapidly. Perturbation of the intestinal microbiota may lead to chronic diseases such as autoimmune diseases, colon cancers, gastric ulcers, cardiovascular disease, functional bowel diseases, and obesity. Restoration of the gut microbiota may be difficult to accomplish, but the use of probiotics has led to promising results in a large number of well-designed (clinical) studies. Microbiomics has spurred a dramatic increase in scientific, industrial, and public interest in probiotics and prebiotics as possible agents for gut microbiota management and control. Genomics and bioinformatics tools may allow us to establish mechanistic relationships among gut microbiota, health status, and the effects of drugs in the individual. This will hopefully provide perspectives for personalized gut microbiota management.

show abstract

“…Similarly in healthy human subjects, there was a decrease in HADS-A scores following ingestion over a 30 day period of formulation consisting of Lactobacillus helveticus and Bifidobacterium longum [24]. In a six-month study that looked at 42 subjects with stress and exhaustion, ingestion of a probiotic multivitamin led to an overall 40.7% improvement in stress [25]. Moreover, consumption of fermented foods that contain probiotics may have a protective effect against social anxiety symptoms in those at high genetic risk for social anxiety disorder [26].…”

Section: Discussionmentioning

confidence: 94%

Gut Microbiota and Anxiety: An Exploration of Key Findings

Ding¹

2017

J Depress Anxiety

View full text Add to dashboard Cite

Effect of a probiotic multivitamin compound on stress and exhaustion

Cited by 33 publications

References 4 publications

Protection and Restitution of Gut Barrier by Probiotics: Nutritional and Clinical Implications

Protection and Restitution of Gut Barrier by Probiotics: Nutritional and Clinical Implications

Probiotics, Prebiotics, and Synbiotics: Gut and Beyond

Gut Microbiota and Anxiety: An Exploration of Key Findings

Contact Info

Product

Resources

About