Effect of a CPP-ACP agent on the demineralization and remineralization of dentine in vitro

Rahiotis, Christos; Vougiouklakis, G

doi:10.1016/j.jdent.2007.05.008

Cited by 153 publications

(140 citation statements)

References 12 publications

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“…6 Clinpro ™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste contains an innovative Tri-Calcium Phosphate ingredient and provides over 4 times more fluoride than regular toothpaste. 3,5 During the manufacturing of Clinpro5000, a protective barrier is created around the calcium allowing it to coexist with the fluoride ions. It acts as a bubble that transports the Tri-Calcium Phosphate to the teeth.…”

Section: Discussionmentioning

confidence: 99%

“…Concentrating mainly on prevention and early intervention of caries, MID's first basic principle is the remineralisation of early carious lesions, advocating a biological or therapeutic approach rather than the traditional surgical approach for early surface lesions. 3 Number of remineralizationtechniques have been tried out, among which the use of fluoride is well known. A newerconcept for remineralization is the use of milk and milk products, which appear to have a protective effect against the development of dental caries.…”

Section: Introductionmentioning

confidence: 99%

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Comparative evaluation of efficacy of CPP-ACPF and Clinpro on enamel remineralization with the help of DIAGNOdent- An invitro study.

Chapla¹,

Shah²,

Parekh³

et al. 2013

Int J of Biomed & Adv Res

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Aim: Comparative evaluation of the efficacy of CPP-ACPF and Sodium fluoride with tri-calcium phosphate on enamel remineralisation using the Diagnodent.

Materials & method: Thirty extracted human premolars were selected and divided into three groups of 10 teeth each: A (artificial saliva), B (CPP-ACPF), C (Sodium fluoride with tri-calcium phosphate -Clinpro 5000). All the samples were assessed using DIAGNOdent at the baseline and after demineralization and remineralisation after 7 days.

Result: Statistical analysis showed that group B(CPP-ACPF) and group C(Clinpro 5000) had significantly higher amount of remineralisation than group A(artificial saliva).

Conclusion: All the three groups showed a statistically significant amount of remineralization. However, Clinpro 5000 showed marginally more amount of remineralisation than CPP-ACPF.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of efficacy of CPP-ACPF and Clinpro on enamel remineralization with the help of DIAGNOdent- An invitro study.

Chapla¹,

Shah²,

Parekh³

et al. 2013

Int J of Biomed & Adv Res

View full text Add to dashboard Cite

Aim: Comparative evaluation of the efficacy of CPP-ACPF and Sodium fluoride with tri-calcium phosphate on enamel remineralisation using the Diagnodent.

Result: Statistical analysis showed that group B(CPP-ACPF) and group C(Clinpro 5000) had significantly higher amount of remineralisation than group A(artificial saliva).

Conclusion: All the three groups showed a statistically significant amount of remineralization. However, Clinpro 5000 showed marginally more amount of remineralisation than CPP-ACPF.

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“…Rahiotis and Vougiouklakis, (2007) investigated the effect of CPP-ACP complex on the demineralisation of sound human dentine in an in vitro study. Dentine in test groups received Tooth Mousse, whereas no Tooth Mousse was provided to the control group.…”

Section: Cpp-acp Effect On Demineralisationmentioning

confidence: 99%

Comparison of the newer preventive therapies on remineralisation of enamel in vitro

Bataineh

Malinowski

Duggal

et al. 2017

Journal of Dentistry

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“…CPP-ACP ürünlerinin klinik kullanım protokolleri henüz geliştirilmemiştir. CPP-ACP süt kazeininden elde edildiği için süt proteinine alerjisi olan çocuklarda önerilmemektedir (33,54). BAKH görülen çocuklarda uygulanacak koruyucu yöntemlerden biri de düzenli aralıklarla uygulanan topikal fluorid vernik ve jelleridir.…”

Section: Sürekli Birinci Büyük Azı Dişlerinde Tedavi Seçenekleriunclassified

Current View on the Diagnosis and Treatment of Molar Incisor Hypomineralization

Güner¹,

Salcıoğlu²

2016

Clin Exp Health Sci

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Yeditepe Üniversitesi Diş Hekimliği Fakültesi, İstanbul, Türkiye Molar incisor hypomineralization (MIH) is defined as the hypomineralization of one or more first permanent molars with or without the involvement of the maxillary and mandibular permanent incisors. Although the etiology of MIH remains unclear, several etiological factors, such as the genetic and environmental factors and systemic disturbance during pre-, peri-, and postnatal period, can cause enamel defects and their occurrence. The prevalence of MIH is reported to be between 2.4% and 25% in different communities. Teeth with MIH are extremely hypersensitive, prone to rapid caries development, and can be difficult to manage in young patients, and thus, dentists may have difficulties during diagnosis, treatment planning, and managing children with MIH during treatment. Early diagnosis is essential because rapid breakdown of tooth structure may occur, resulting in acute symptoms and complicated treatment. This study aimed to review the diagnosis and etiological factors involved in the occurrence of MIH and to evaluate treatment approaches in the management of MIH. Keywords: Molar incisor hypomineralization, children, incisor, molar GİRİŞ Tanımı ve Oluşum MekanizmasıBir veya birkaç sürekli birinci büyük azı dişi ile birlikte sürekli keser dişlerinde etkilenebildiği, etiyolojisi tam olarak bilinmeyen, amelogenezisin olgunlaşma safhasında gözlenen, sistemik kaynaklı klinik hipomineralizasyona büyük azı keser hipomineralizasyonu (BAKH) denir (1). Son yıllarda yapılan çalışmalarda BAKH'nin sadece daimi dişleri etkilediği düşünülürken, Elfrink ve ark. (2) süt dişlerinde de BAKH görüldüğünü bildirmişler ve süt dişlerinin etkilendiği bu hipomineralizasyonu "süt azı keser hipomineralizasyonu" olarak tanımlamışlardır (2, 3). Doku anomalileri dişlerin organik matriks yapımı ve mineralizasyonunun histogenez döneminde karşılaştığı etkenler sonucunda meydana gelmektedir. Amelogenezis 3 ana evreden oluşur (4). Salgılama Evresi: Ameloblastlar mine matriks proteini üretirler. Mine oluşumu öncelikle tüberkül tepelerinden başlar ve servikale doğru ilerler. Hidroksiapatit kristalleri uzayarak büyümeye başlar ve bu sayede mine tabakası kalınlaşır. Bu evrede minenin %20'si mineralden oluşurken geri kalan kısmı ise su ve mine matriks proteininden oluşmaktadır (4).Geçiş Evresi: Mine matriks salgılanması sonucunda mine tam kalınlığına ulaşır. Ameloblastlar olgunlaşma evresindeki ameloblastlara dönüşür (4).Olgunlaşma Evresi: Olgun ameloblastlar mineralizasyonu düzenlerler ve mine tabakası sertleşir, kalınlaşır, kristaller büyür, mineralizasyonun %95'i tamamlanmış olur. Doğumda sekonder mineralizasyon tüberkül tepelerinden itibaren başlar ve mineralizasyon doğumdan sonraki 1 yıl boyunca devam eder (4).

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Effect of a CPP-ACP agent on the demineralization and remineralization of dentine in vitro

Cited by 153 publications

References 12 publications

Comparative evaluation of efficacy of CPP-ACPF and Clinpro on enamel remineralization with the help of DIAGNOdent- An invitro study.

Comparative evaluation of efficacy of CPP-ACPF and Clinpro on enamel remineralization with the help of DIAGNOdent- An invitro study.

Comparison of the newer preventive therapies on remineralisation of enamel in vitro

Current View on the Diagnosis and Treatment of Molar Incisor Hypomineralization

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