Effect of a combination of arterial hypertension and insulin resistance on hemostasis activity

Zavalishina, S. Yu.; Vatnikov, Yuri Anatolyevich; Kulikov, Evgeny Vladimirovich; Kubatbekov, T. S.; Vilkovysky, I. F.; Petrov, Alexander Konstantinovich; Tishchenko, A. L.; Drukovsky, Stanislav Gennadievich; Жаров, А. Н.; Grishin, Victor Nikolaevich; Glagoleva, T

doi:10.15562/bmj.v8i1.1151

Cited by 3 publications

(2 citation statements)

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“…The results of this study follow research by Epcacan et al, 2019, the average age of children with pulmonary artery hypertension caused by CHD is 4-5 years old 17. Research at RSUD Dr. Soetomo by Sidqoh 2020 stated that the characteristic distribution of PAH was caused by congenital heart disease at 0-5 years (86.67) 18.…”

supporting

confidence: 84%

Effect of Pomegranate Extract On N-Terminal Pro Brain Natriuretic Peptide and Asymmetric Dimetylarginine Levels in Children with Pulmonary Artery Hypertension in Acyanotic Congenital Heart Disease

Noer¹,

Rahman²,

Utomo³

2023

Pharmacogn J.

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Background: Pulmonary arterial hypertension (PAH) is one of the complications due to acyanotic congenital heart disease. New treatment approach using natural ingredients from plants has been demonstrated in vitro to prevent and improve vascular remodeling in PAH. Objective: This study aimed to analyze the effect of pomegranate extract on N-terminal pro brain natriuretic peptide (NT pro BNP) and asymmetric dimethylarginine (ADMA) levels in children with PAH in acyanotic CHD. Method: This study is a double-blind, quasi-experimental text with pre-test, post-test, and control group approach to children aged one month to 10 years old in Outpatient

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supporting

confidence: 84%

Effect of Pomegranate Extract On N-Terminal Pro Brain Natriuretic Peptide and Asymmetric Dimetylarginine Levels in Children with Pulmonary Artery Hypertension in Acyanotic Congenital Heart Disease

Noer¹,

Rahman²,

Utomo³

2023

Pharmacogn J.

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“…The ongoing scientific research is increasingly aimed at studying in detail the main stages of the implementation of aging and the processes of formation of age-related pathology with a deep consideration of the mechanisms of gerontogenesis on various models (Klebanov et al, 2019). Modern researchers attach particular importance to monitoring various parameters of blood cells (Kulikov et al, 2020) and especially the most numerous group -erythrocytes (Zavalishina et al, 2018) in different conditions of the body (Zavalishina et al, 2019) and of course in the course of aging (Vakhtin, 2009). The significance of these studies is that aging affects the state of all cells in the body, as a rule, leading to a weakening of their work, with the occurrence of dysfunctions, and sometimes pathological processes.…”

Section: Introductionmentioning

confidence: 99%

Physiological Features of Erythrocytes in the Aging Organism

Tkacheva¹,

Медведев²,

Vorobyeva³

et al. 2023

J Biochem Technol

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The progression of aging affects various blood parameters, which can weaken the viability of the body. Clarification of various aspects of this process requires additional observations, especially with the use of animals. The study was conducted on 43 healthy outbred male rats aged 24 months. Also, 32 healthy outbred male rats 3 months old, which formed the control group, were taken under observation. The examined 24-month-old rats showed standard aging phenomena. In their erythrocytes, there was an increase in lipid peroxidation caused by a weakening of the activity of their antioxidant defense. In the blood of two-year-old rats, there was a decrease in the level of erythrocyte-discocytes. This was accompanied in them by an excess content of erythrocytes in the blood, which had a changed shape to varying degrees. In rats of the older group, erythrocyte aggregation was increased, as indicated by an increase in the numberof erythrocytes that entered the aggregates in the blood and an increase in the number of most erythrocyte aggregates with a decrease in the level of free erythrocytes. For two-year-old rats, low content of erythrocytesdisconcytes in the blood and an excess number of erythrocytes with a modified shape, as well as an increase in their aggregation, are characteristics. An important reason for these changes is the weakening of the antioxidant protection of erythrocytes, leading to a pronounced activation of lipid peroxidation in them.

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Physiological Changes in the Erythrocytes of an Aging Organism Experiencing Physical

Kartashev¹,

Sun²,

Медведев³

et al. 2022

J Biochem Technol

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Effect of a combination of arterial hypertension and insulin resistance on hemostasis activity

Cited by 3 publications

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Effect of Pomegranate Extract On N-Terminal Pro Brain Natriuretic Peptide and Asymmetric Dimetylarginine Levels in Children with Pulmonary Artery Hypertension in Acyanotic Congenital Heart Disease

Effect of Pomegranate Extract On N-Terminal Pro Brain Natriuretic Peptide and Asymmetric Dimetylarginine Levels in Children with Pulmonary Artery Hypertension in Acyanotic Congenital Heart Disease

Physiological Features of Erythrocytes in the Aging Organism

Physiological Changes in the Erythrocytes of an Aging Organism Experiencing Physical

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