Effect of a Brown Algae Extract on Postprandial Glucose Control in Neonatal Diabetic and Obese Rats

Nam, Jeongsu; Lee, Wonjun; Yoon, Imsil; Kang, Min Jae; Jang, Hyunsoo; Youn, Jihye; Kim, Boram; Kong, Hyejoo; Kim, Ki-Hoon; Kim, Yong-Ho; Lee, Dongseok; Choi, Hyunju

doi:10.1096/fasebj.21.6.a1085

Cited by 2 publications

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“…These findings suggested that T. decurrens acetone extract might slow the absorption of dietary carbs, hence preventing a rise in postprandial blood glucose levels. In a previous study, brown algae extract was shown to have a beneficial effect in controlling postprandial glucose levels in diabetic obese rats [127].…”

Section: Effect Of Algal Treatment On the Blood Glucose Levels Of Dia...mentioning

confidence: 93%

Antioxidant and Antidiabetic Activity of Algae

Abo-Shady¹,

Gheda²,

Ismail³

et al. 2022

Preprint

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Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological, cosmetic, and nutraceutical applications. Many of these bioactive compounds are secondary metabolites whose amounts in the algae vary with varying environmental conditions. Free radicals and other active oxygen derivatives are recognized as a natural by-product of aerobic metabolism. However, reactive oxygen species directly participate in mechanisms related to various pathological states such as cancer, diabetes, atherosclerosis, Alzheimer's, and Parkinson's, among others. Diabetes mellitus (DM) is a metabolic disease resulting from changes in glucose metabolism and/or deficient production/action of insulin. This review has as its main objective to reveal the potential antioxidant and antidiabetic capacity of algae extracts.

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Section: Effect Of Algal Treatment On the Blood Glucose Levels Of Dia...mentioning

confidence: 93%

Antioxidant and Antidiabetic Activity of Algae

Abo-Shady¹,

Gheda²,

Ismail³

et al. 2022

Preprint

View full text Add to dashboard Cite

Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological, cosmetic, and nutraceutical applications. Many of these bioactive compounds are secondary metabolites whose amounts in the algae vary with varying environmental conditions. Free radicals and other active oxygen derivatives are recognized as a natural by-product of aerobic metabolism. However, reactive oxygen species directly participate in mechanisms related to various pathological states such as cancer, diabetes, atherosclerosis, Alzheimer's, and Parkinson's, among others. Diabetes mellitus (DM) is a metabolic disease resulting from changes in glucose metabolism and/or deficient production/action of insulin. This review has as its main objective to reveal the potential antioxidant and antidiabetic capacity of algae extracts.

show abstract

“…These findings suggested that T. decurrens acetone extract might slow the absorption of dietary carbohydrates, hence preventing the rise in postprandial blood glucose levels. In a former study, extracts of some brown algae species exposed a beneficial effect in controlling postprandial glucose levels in diabetic obese rats [ 125 ].…”

Section: Treatment Of Diabetesmentioning

confidence: 99%

Antioxidant and Antidiabetic Activity of Algae

Abo-Shady

Gheda

Ismail

et al. 2023

Life

View full text Add to dashboard Cite

Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes mellitus, a metabolic illness, is the third largest cause of death globally. The hunt for an efficient natural-based antidiabetic therapy is crucial to battling diabetes and the associated consequences due to the unfavorable side effects of currently available antidiabetic medications. Finding the possible advantages of algae for the control of diabetes is crucial for the creation of natural drugs. Many of algae’s metabolic processes produce bioactive secondary metabolites, which give algae their diverse chemical and biological features. Numerous studies have demonstrated the antioxidant and antidiabetic benefits of algae, mostly by blocking carbohydrate hydrolyzing enzyme activity, such as α-amylase and α-glucosidase. Additionally, bioactive components from algae can lessen diabetic symptoms in vivo. Therefore, the current review concentrates on the role of various secondary bioactive substances found naturally in algae and their potential as antioxidants and antidiabetic materials, as well as the urgent need to apply these substances in the pharmaceutical industry.

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Effect of a Brown Algae Extract on Postprandial Glucose Control in Neonatal Diabetic and Obese Rats

Cited by 2 publications

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Antioxidant and Antidiabetic Activity of Algae

Antioxidant and Antidiabetic Activity of Algae

Antioxidant and Antidiabetic Activity of Algae

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