Abstract:The effect of Vesiculogen (a hot-water extracted B cell mitogen from Peziza vesiculosa) on antibody production in mouse spleens was studied. The number of plaque-forming cells (PFC) elicited by injection with Vesiculogen and/or 2,4,6-trinitrophenyl substituted sheep red blood cells (TNP-SRBC) were comparatively assayed. In the mice injected with 100 micrograms of Vesiculogen (i.p.), an obvious increase in the numbers of anti-SRBC and anti-TNP SRBC PEC in spleens was observed after 2 d of injection, and the num… Show more
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