Effect of 1000 or More ppm Relative to 440 to 550 ppm Fluoride Toothpaste - A Systematic Review

Cadavid, Alexandra Saldarriaga; Hernández, Rubén Darío Manrique; Lince, Clara María Arango

doi:10.5772/38315

Cited by 1 publication

(1 citation statement)

References 25 publications

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“…The results are in line with several studies indicating low protection levels in toothpastes with low fluorine content compared to those with higher concentrations [28–30]. Although the validity of with low doses of fluorine is controversial, it lowers the risk of fluorosis by accidental ingestion of the product [31, 32]. Studies on the samples treated with Biomimetic Hydroxyapatite toothpaste show a homogeneous surface, in which the roughness of the demineralized enamel are repaired and smoothly leveled.…”

Section: Discussionsupporting

confidence: 87%

Enamel remineralization and repair results of Biomimetic Hydroxyapatite toothpaste on deciduous teeth: an effective option to fluoride toothpaste

et al. 2019

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BackgroundDental caries is a recognized worldwide public health problem. Despite being one of the most effective strategies against dental caries, the excessive use of fluorine may result in a potential risk of developing dental fluorosis especially in children under age of six. The purpose of this work is to analyze a fluorine-free toothpaste containing Biomimetic Hydroxyapatite to assess enamel re-mineralizing and repairing properties.ResultsThe study was performed in vitro and in vivo, comparing the hydroxyapatite toothpaste with two others toothpaste containing different fluorine concentrations. The coating effect of the micro-structured Hydroxyapatite nanoparticles reintegrates the enamel with a biomimetic film reproducing the structure and the morphology of the biologic Hydroxyapatite of the enamel. As demonstrated, the coating is due to the deposit of a new layer of apatite, which presents fewer particles than the natural enamel, not based on the chemical—physical changes occurring in fluorinated toothpastes. Moreover, it shows resistance to brushing as a consequence of chemical bonds between the synthetic and natural crystals of the enamel.ConclusionsThe use of Biomimetic Hydroxyapatite toothpastes has proven to be a valuable prevention measure against dental caries in primary dentition since it prevents the risk of fluorosis.

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Section: Discussionsupporting

confidence: 87%