Efecto de terapias farmacológicas para el control glicémico en pacientes con diabetes mellitus tipo 2 en los desenlaces vasculares

Vargas, John M.; Fontalvo, Jorge Eduardo Rico; R, Enrique Melgarejo; Barrios, Gilberto Amed Castillo; Rincón, Alex Ramírez; Gómez, Ana María; Rojas, Susan; Bernai, Linda Ibatá

doi:10.22265/acnef.7.1.372

Cited by 7 publications

(8 citation statements)

References 61 publications

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“…The authors conclude that in patients with DM2, more advanced CKD was associated with greater insulin use, proposing different explanations of this relationship, however, we consider that in addition to these findings, within the study there are no patients using Dipeptidyl Peptidase-4 Inhibitors (DPP4i), probably by that time they were not being used yet [2]. Therefore, patients with advanced CKD only had insulin as the only option, which explains a greater frequency of its use in this group of patients [3].…”

mentioning

confidence: 75%

Severe hypoglycemia: Is it important to take into account the albuminuria value?

Rico-Fontalvo

Daza-Arnedo

Bohórquez-Rivero

et al. 2023

Rev. Colomb. Nefrol.

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The authors conclude that in patients with DM2, more advanced CKD was associated with greater insulin use, proposing different explanations of this relationship, however, we consider that in addition to these findings, within the study there are no patients using Dipeptidyl Peptidase-4 Inhibitors (DPP4i), probably by that time they were not being used yet. Therefore, patients with advanced CKD only had insulin as the only option, which explains a greater frequency of its use in this group of patients.

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mentioning

confidence: 75%

Severe hypoglycemia: Is it important to take into account the albuminuria value?

Rico-Fontalvo

Daza-Arnedo

Bohórquez-Rivero

et al. 2023

Rev. Colomb. Nefrol.

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“…Therefore, the continuous search for novel biomarkers in urine and serum, based on proteomics and metabolomics, has gained relevance in recent years. This is due to the improved understanding of the pathophysiology and mechanisms associated with the development of DKD [ 23 , 25 ].…”

Section: Novel Biomarkers In Diabetic Kidney Diseasementioning

confidence: 99%

Novel Biomarkers of Diabetic Kidney Disease

et al. 2023

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Diabetic kidney disease (DKD) is a highly prevalent condition worldwide. It represents one of the most common complications arising from diabetes mellitus (DM) and is the leading cause of end-stage kidney disease (ESKD). Its development involves three fundamental components: the hemodynamic, metabolic, and inflammatory axes. Clinically, persistent albuminuria in association with a progressive decline in glomerular filtration rate (GFR) defines this disease. However, as these alterations are not specific to DKD, there is a need to discuss novel biomarkers arising from its pathogenesis which may aid in the diagnosis, follow-up, therapeutic response, and prognosis of the disease.

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“…Algunos hipoglucemiantes han demostrado un enlentecimiento de la progresión del daño renal, incluso en pacientes con ERC estadio III con HbA1c entre 7 % y 8 % [44]. Por su parte, los inhibidores del transportador sodio-glucosa tipo 2 (SGLT2i) y péptido similar a glucagón-1 pueden generar bene cios adicionales al control de la glicemia como mejorar los desenlaces renales y cardiovasculares.…”

Section: Prevención Secundariaunclassified

Modelo ideal de nefroprevención para Colombia

Perez

Torres

et al. 2021

Rev. Colomb. Nefrol.

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La enfermedad renal crónica (ERC) es una patología altamente prevalente en países en vía de desarrollo como Colombia, en donde afecta a gran parte de la población. Esta es una enfermedad que afecta la calidad de vida y la longevidad de los pacientes, así como los costos del sistema de salud. La ERC tiene un carácter progresivo e irreversible, por lo que intervenirla en etapas tempranas resulta ser una medida altamente costo-efectiva; a partir de esto surge el concepto de nefroprevención, mediante la cual, teniendo en cuenta los niveles de prevención primaria, secundaria y terciaria, se puede lograr una identificación precoz y la interrupción o enlentecimiento de la progresión, y además se puede implementar un manejo oportuno e integral del daño renal según el estadio de la enfermedad. Esto es posible haciendo una búsqueda activa de casos, realizando pruebas de cribado y haciendo intervenciones interdisciplinarias que incluyan educación de la población y del personal en salud, para así promover el autocuidado y realizar un seguimiento que impacte de forma positiva en la calidad de vida de los pacientes, en los desenlaces de la enfermedad y en la economía de los países en vía de desarrollo, los cuales deben optimizar sus limitados recursos e invertir en los procesos que generen mayor costo-efectividad.

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Efecto de terapias farmacológicas para el control glicémico en pacientes con diabetes mellitus tipo 2 en los desenlaces vasculares

Abstract: Efecto de terapias farmacológicas para el control glicémico en pacientes con diabetes mellitus tipo 2 en los desenlaces vascularesEffect of pharmacological therapies for glycemic control in patients with type 2 diabetes mellitus on vascular outcomes

Cited by 7 publications

References 61 publications

Severe hypoglycemia: Is it important to take into account the albuminuria value?

Severe hypoglycemia: Is it important to take into account the albuminuria value?

Novel Biomarkers of Diabetic Kidney Disease

Modelo ideal de nefroprevención para Colombia

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