EEF1D (eukaryotic translation elongation factor 1 delta)

Abstract

Eukaryotic translation elongation factor 1 delta, alias EEF1D, is a protein-coding gene that plays a role in the elongation step of translation and considering its importance it is found frequently overexpressed in human cancer cells. This review collects the data on DNA/RNA, on the protein encoded and on the diseases where EEF1D is involved.

The pseudogenes of eukaryotic translation elongation factors (EEFs): Role in cancer and other human diseases

“…EEF1D , alias eEF1δ or eEF1Bδ , is a coding gene with several alternative splicing transcript variants that encode several protein isoforms. 58 Like the other members of the eEF1H complex, it is involved in the elongation step of translation and closely collaborates with eEF1B2 in the conversion of eEF1A from its inactive GDP-bound form to its active GTP-bound form. 56 , 57 Analysis of the human genome revealed the presence of eight pseudogenes.…”