Editorial

Lr, Eversole

doi:10.1016/0030-4220(92)90015-i

Cited by 9 publications

(1 citation statement)

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“…Other forms of LP include reticular, papular, and plaque types, with the plaque form more frequently encountered among tobacco users 4,5 . When in the oral cavity, LP predominantly occurs on the buccal mucosa (80%‐99%) but is also seen on the dorsal or lateral tongue (13%‐38%) and is frequently multifocal and bilateral 6‐8 …”

Section: Introductionmentioning

confidence: 99%

Oral Lichen Planus and Its Association With Squamous Cell Carcinoma: An Update on Pathogenesis and Treatment Implications

1996

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Lichen planus of the oral mucosa (OLP) is characterized by lymphocytic mucositis, basal cell lysis, and lymphocyte transmigration into the epithelial compartment. Some reports have suggested a high incidence of oral squamous cell carcinoma (OSCCA) in OLP patients and have implicated OLP as a premalignant lesion. We describe five cases of OSCCA arising in patients with preexisting OLP. At our institution, the incidence of OSCCA in patients with OLP approximates that reported in other series. The immunopathologic basis for OLP, its potential association with malignancy, and the variable clinical picture of OSCCA in patients with OLP are reviewed. Specific recommendations are given for treatment and follow-up of lesions, including the role of future testing with viral and oncogene markers.

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Section: Introductionmentioning

confidence: 99%

Oral Lichen Planus and Its Association With Squamous Cell Carcinoma: An Update on Pathogenesis and Treatment Implications

1996

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Clinical guidelines in early detection of oral squamous cell carcinoma arising in oral lichen planus: a 5-year experience

et al. 2001

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Oral cancer in the UK: to screen or not to screen

1998

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Although oral squamous cell carcinoma accounts for only a small proportion of malignant neoplasms in the UK, oral cancer incidence and mortality rates have been rising in recent years. The natural history of oral cancer is not adequately understood at present and there is very little information about the epidemiology of precancerous lesions in the UK. There are also insucient data to provide ®rm evidence that the percentage of cases arising de novo is greater in the UK and the Western world as compared to the Indian subcontinent. Screening for oral cancer by visual examination is simple, inexpensive and causes little discomfort; however, there is no evidence for the eectiveness of screening for oral cancer either in reducing mortality from the disease or in reducing the incidence of invasive disease by detection and treatment of precancerous lesions. There is currently insucient evidence to recommend population screening for oral cancer in the UK. Measures aimed at primary prevention of the disease may be a more feasible method of disease control at present. #

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Editorial

Cited by 9 publications

References 0 publications

Oral Lichen Planus and Its Association With Squamous Cell Carcinoma: An Update on Pathogenesis and Treatment Implications

Oral Lichen Planus and Its Association With Squamous Cell Carcinoma: An Update on Pathogenesis and Treatment Implications

Clinical guidelines in early detection of oral squamous cell carcinoma arising in oral lichen planus: a 5-year experience

Oral cancer in the UK: to screen or not to screen

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