Edema within Epiretinal Proliferation in a Diabetic Patient

Abstract

Edema within Epiretinal Proliferation in a Diabetic PatientA 40-year-old woman with proliferative diabetic retinopathy status post tractional retinal detachment repair of the right eye was found to have a lamellar hole with epiretinal proliferation (Fig A). Four years later, her visual acuity declined from 20/400 to count fingers. OCT showed interval development of cystoid macular edema and cystoid spaces within the epiretinal proliferation (Fig B). Arrows localize the OCT scans on the infrared image. To our knowledge, cystoid spaces within epiretinal proliferation have not previously been reported in diabetic retinopathy. The concurrent development of epiretinal and macular edema suggests either fluid flux between the middle retina and the epiretinal material or vascular structures within the epiretinal material. Future studies with OCT-angiography could distinguish these hypotheses.

Lamellar Macular Hole-Associated Epiretinal Proliferation with Cystoid Changes: Long-term Follow-up

“…The formation of cystoid spaces in EP and the inner nuclear layer in the same time interval may indicate similar mechanisms for this development. Intra-EP fluid due to exudative vascular complex in EP and diabetic macular edema have been reported in case reports 6 , 7 . Our case was different from the previous ones in that there was no vascular formation, no underlying retinal pathology, and the cavities kept their angular appearance.…”

“…The EP area may increase with the progression of the LMH 5 . Cystoid changes within EP have been reported in cases accompanied by various retinal pathologies 4 , 6 , 7 . We present a case of an LMH associated with EP, without any other accompanying retinal disorder that developed cystoid changes within the EP during a long-term follow-up of 8 1/2 years.…”