A 55-year-old man, a retired bricklayer, born in Itapetim (State of Pernambuco, Brazil), sought medical care due to shortness of breath (11/04/2005). Three years earlier, he had started to develop progressive worsening of dyspnea, which was initially triggered by severe exertion. One year earlier, dyspnea started to be triggered by moderate exertion and was associated with tachycardic palpitations. The patient sought medical care in a primary health care unit where he was prescribed medications, the names of which he could not recall. He improved after the use of these medications. He had been previously diagnosed with Chagas disease. The patient was receiving carvedilol 3.125 mg bid, digoxin 0.25 mg, spironolactone 25 mg, acetylsalicylic acid 100 mg, and hydrochlorothiazide 12.5 mg in combination with amiloride 1.25 mg daily. Physical examination revealed weight of 74.8 kg, height of 1.64 m, body mass index of 27.8 kg/m 2 , pulse of 78 beats per minute, and blood pressure of 110/80 mmHg. Lung examination was normal. Heart examination revealed normal heart sounds, regular rhythm, no extra sounds, clicks or murmurs. Abdominal examination was normal. There was no leg edema. Electrocardiogram (11/01/2005) showed sinus rhythm and low-amplitude R-waves in limb and precordial leads; intraventricular conduction abnormality; left ventricular; and atrial overload (Figure 1). Chest radiography showed grade 3/4 cardiomegaly. A diagnosis of heart failure secondary to chagasic cardiomyopathy was made. Medication adjustment was made with discontinuation of acetylsalicylic acid and of the combination hydrochlorothiazide/ amiloride, and increase in the carvedilol dose to 6.25 mg bid; enalapril was added at 10 mg bid. A test for detection of anti-Trypanosoma cruzi antibody was positive (11/3/2005).