Ectopic Pacinian Corpuscle in the Prostate

Pai, Sanjay A

doi:10.1177/1066896917705200

Cited by 10 publications

(8 citation statements)

References 6 publications

(5 reference statements)

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“…The occurrence of ectopic Pacinian corpuscle is rare. In the scientific literature, there are reports of its sporadic presence in the pancreas [9,11], in the lymph node [12][13][14][15], inside the prostate [16,17] and the urinary bladder wall [18]. In animals, the Pacinian corpuscle was found in the mesentery of cats [19] and nerve endings similar to the Pacinian corpuscles were also described in the lungs of Indian black rats [20].…”

Section:  Discussionmentioning

confidence: 99%

Ectopic lamellar Pacinian corpuscle within the thymus. Atypical or abnormal location?

Varga

Nosál²,

Babál³

2020

Rom J Morphol Embryol

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Lamellar (Pacinian) corpuscle is a cutaneous encapsulated sensory corpuscle, mainly functioning as a rapidly adapting low-threshold mechanoreceptor with characteristic "onion skin"-like appearance. Even though the Pacinian corpuscle is typically located in the skin, histomorphologically and confirmed by using immunohistochemical methods, we have identified it within the interstitium of the thymus of a newborn with congenital heart defect. To the best of our knowledge, this is the first such account ever to be published. The structure of the thymic Pacinian corpuscle was the same as the Pacinian corpuscle in the skin. The ectopic thymic Pacinian corpuscle can be hypothetically explained as the consequence of impaired migration of neural crest cells, since neural crest-derived cells play an important role in the development of the Pacinian corpuscle, as well as the thymus and heart. In general, the occurrence of ectopic Pacinian corpuscle in different organs is rare. In the scientific literature, there are reports of its sporadic presence in the pancreas, in the lymph nodes, inside the prostate and the urinary bladder wall. Our report presents the first described case of the Pacinian corpuscle in a heterotopic location in the thymus. Similar to other incidental findings of this anatomic structure, explanation of its ectopic development, as well as its local function remains only speculative.

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Section:  Discussionmentioning

confidence: 99%

Ectopic lamellar Pacinian corpuscle within the thymus. Atypical or abnormal location?

Varga

Nosál²,

Babál³

2020

Rom J Morphol Embryol

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“…The presence of many Pacinian corpuscles (i.e., lamellar corpuscles) within the stroma of the circumorbital gland in the bowhead whale is intriguing. Rare reports of ectopic Pacinian corpuscles in glandular tissue (e.g., prostate, pancreas), and lymphatic tissues have been reported in humans (Feito, Cobo, Santos-Briz, & Vega, 2017;García-Suárez et al, 2010;Pai, 2017;Standop, Ulrich, Schneider, Andrén-Sandberg, & Pour, 2001). The physiological significance of these anatomical rarities is unknown.…”

Section: Gland Structurementioning

confidence: 99%

Whale tear glands in the bowhead and the beluga whales: Source and function

Rehorek

Stimmelmayr

George

et al. 2020

Journal of Morphology

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Orbital glands are found in many tetrapod vertebrates, and are usually separate structures, consisting of individual glands lying in the eyelids and both canthi of the orbit. In cetaceans, however, the orbital glandular units are less distinct and have been described by numerous authors as a single, periorbital mass. There are few histochemical and immunhistochemical studies to date of these structures. In this study, we examined the orbital glandular region of both the bowhead whale (Balaena mysticetus: Mysticeti) and the beluga whale (Delphinapterus leucas: Odontoceti) using histological, histochemical, and immunohistochemical techniques. Histologically, in the bowhead, three glandular areas were noted (circumorbital, including Harderian and lacrimal poles), palpebral (midway in the lower eyelid), and rim (near the edge of the eyelid). In the beluga, there was only a large, continuous mass within the eyelid itself. Histochemical investigation suggests neither sexual dimorphism nor age‐related differences, but both whales had two cell types freely intermingling with each other in all glandular masses. Large cells (cell type 1) were distended by four histochemically distinct intracellular secretory granules. Smaller cells (cell type 2) were not distended (fewer granules) and had two to three histochemically distinct intracellular secretory granules. The beluga orbital glands had additional lipid granules in cell type 1. Counterintuitively, both lipocalin and transferrin were localized to cell type 2 only. This intermingling of cell types is unusual for vertebrates in whom individual orbital glands usually have one cell type with one to two different secretory granules present. The heterogeneity of the orbital fluid produced by cetacean orbital glands implies a complex function, or series of functions, for these orbital glands and their role in producing the tear fluid.

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“…Pacinian corpuscle, also known as lamellated corpuscle or Vater-Pacinian corpuscle, is a mechano-receptor sensing rapid vibration, pressure, and coarse touch. It is located predominantly in the dermal and subcutaneous tissues of the skin (mainly non-hairy), and has also been commonly reported in mesentery, nipples, genitals, ligaments, tendons, and periosteum [1,2]. Rare reports of ectopic Pacinian corpuscle in human beings have described it in the urinary bladder [3], pancreas [4], and prostate [2].…”

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confidence: 99%

“…It is located predominantly in the dermal and subcutaneous tissues of the skin (mainly non-hairy), and has also been commonly reported in mesentery, nipples, genitals, ligaments, tendons, and periosteum [1,2]. Rare reports of ectopic Pacinian corpuscle in human beings have described it in the urinary bladder [3], pancreas [4], and prostate [2]. Some authors have also described its unusual presence in human lymph nodes, with a total of 8 cases so far mentioned in 5 reports [1,[5][6][7][8] (Table 1).…”

mentioning

confidence: 99%