Ectopic nephrogenic rest in the inguinal canal in a 6-month-old girl and a review of published studies

Abstract

Ectopic nephrogenic rests in the inguinal canal are rare. Usually discovered incidentally during surgery, these rests should raise the suspicion of an early extrarenal Wilms tumor. The differential diagnosis between the two entities is not only difficult but also essential, since they imply different treatment decisions. We report a rare case of an inguinal ectopic nephrogenic rest found in a 6-month-old girl and discuss the clinicopathological implications of this condition. The patient was admitted for a routine repair of a presumed inguinal hernia; during suregry, a nodular mass was noted in the inguinal canal. Pathological diagnosis confirmed the diagnosis of an extrarenal hyperplastic nephrogenic rest. Five previous cases of ectopic nephrogenic rests originating in the inguinal canal have been reported, all of which were associated with a patent processus vaginalis. In this case, the nephrogenic rest was not associated with a congenital inguinal hernia.

Nephrogenic remnants: occasional ultrasound diagnosis and follow-up

“…In consideration of the accelerated growth rate of the lesion, we recommend elective surgery because of the potential evolution in WT. [8][9][10] In conclusion, NRs can be incidentally identified in a preclinical stage in the course of a sonographic exam done for other purposes. Most will regress, but when detected, serial abdominal US in a specialized center are mandatory.…”

Ectopic nephrogenic rests in children: A series of 13 cases in a single institution

“…Approximately 47 cases (including our 10 cases) have been reported . Approximately 80% of the patients were less than 10 years old, and most were infants, including several congenital cases.…”

Coexistence of Extrarenal Wilms’ tumor and Ganglioneuroblastoma in a child and literature review

“…Normalde mezonefroz ise gestasyonun 16. haftasında dejenere olur, ancak jukstagonadal mezonefrik glomerüller 21. haftaya kadar gecikebilir (12) . Bu dokulardan köken alan ektopik nefrojenik kalıntılardan, olgumuzda da görüldüğü gibi, inguinal bölge yerleşimli ERWT'in oluşmuş olabileceği iddia edilmektedir (1) .…”

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Abstract

Coexistence of Extrarenal Wilms tumor and ganglioneuroblastoma in a child and literature review

It is quite uncommon for multiple malignant tumors to ap-

GirişEktopik nefrojenik kalıntılardan köken alan ve gö-ğüs boşluğu ile skrotum arasında herhangi bir alanda yerleşen ekstrarenal Wilms tümörlerinin (ERWT) en sık lokalizasyon yeri retroperitondur, inguinal kanal yerleşimli ERWT ise çok enderdir (1,2) . Ganglionö-roblastomalar histolojik özellikleri, ganglionorom ve nöroblastom arasında yer alan, diferansiye nöroblast-ların hâkim olduğu kapsüllü olmasına rağmen, lokal invazyon yapabilen periferik nöroblastik tümörlerden (pNTs) biridir.

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