Ecotoxicological study on sediments of Mai Po marshes, Hong Kong using organisms and biomarkers

Kwok, Chun Kit; Yang, Shumin; Mak, Nai Ki; Wong, Chun Kit; Liang, Yan; Leung, S. Y.; Young, Leah Bendell; Wong, Ming Hung

doi:10.1016/j.ecoenv.2010.01.012

Cited by 16 publications

(2 citation statements)

References 44 publications

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“…Thus, the protein has been considered a suitable biochemical marker for metal exposure. Previous studies employed the MT proteins to monitor the coastal sediments which are contaminated by heavy metals (Wong et al 2000;Kwok et al 2010). In the present study, MT protein is used to assess the changes of co-exposure by heavy metals, and to investigate the influence of heavy metals on the induction of MT protein on human cell lines.…”

Section: Introductionmentioning

confidence: 99%

Cadmium, lead, and arsenic contamination in paddy soils of a mining area and their exposure effects on human HEPG2 and keratinocyte cell-lines

Xue

Shi

et al. 2017

Environmental Research

171

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A mining district in south China shows significant metal(loid) contamination in paddy fields. In the soil, Pb, Cd and As were 516.7, 11.7 and 35.1 mg•kg-1 respectively. The content of Cd exceeded the environmental quality standard for agricultural soils in China by approximately 82%. The contents of Pb, Cd and As in rice were 22.7, 1.1 and 0.7 mg•kg-1 respectively. These concentrations are also higher than the agricultural industry standard of China for rice. The elevated contents of Pb, Cd and As detected in soils around the factories, indicated that their spatial distribution was influenced by anthropogenic activity. Greater concentrations of Cd in rice appeared in the northwest region of the factories, indicating that the spatial distribution of heavy metals was affected by natural factors. The metals affected the viability of HepG2 and KERTr cells, which decreased with increasing metal concentration. Co-exposure to heavy metals (Pb+Cd) increased the metals (Pb or Cd)-mediated MT protein induction in both human HepG2 and KERTr cells. Increased levels of MT protein will lead to greater risk of carcinogenic manifestations, and it is likely that chronic exposure to metals may increase the risk to human health. Nevertheless, when co-exposure to two or more metals occur (such as As+Pb), they may have an antagonistic effect thus reducing the toxic effects of each other.

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Section: Introductionmentioning

confidence: 99%

Cadmium, lead, and arsenic contamination in paddy soils of a mining area and their exposure effects on human HEPG2 and keratinocyte cell-lines

Xue

Shi

et al. 2017

Environmental Research

171

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“…Many different approaches may be used in sediment quality assessment. Among them, chemical analyses and toxicity testing are the most commonly used around the world (Ingersoll et al 2002;Kwok et al 2010;Losso et al 2004). Chemical analyses consist in listing de contaminants and quantifying the contaminants and their respective concentrations.…”

Section: Introductionmentioning

confidence: 99%

Physicochemical and ecotoxicological based assessment of bottom sediments from the Luján River basin, Buenos Aires, Argentina

Peluso

Rossini

Salibián

et al. 2012

Environ Monit Assess

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The physicochemical analysis of bottom sediments of the Lujan River was done on samples from 14 sites situated along its course and covered grain size and organic matter, total N and P, sulfides, heavy metals, organochlorine, and pyrethroid pesticides. In addition, acute 10-day whole-sediment laboratory toxicity tests were carried with each sample, using the native amphipod Hyalella curvispina as test organism. In order to correlate both types of results, data were assessed by multivariate analysis, including principal component analysis (PCA). The physicochemical profile of samples resulted similar along the river course, though several anomalous data were registered in the middle course of the river, mainly in samples taken downstream a large industrial complex; with a few exceptions in upper basin sites characterized by the dominance of agricultural activities, the pesticides concentration were consistently below the analytical detection limits. Almost 50% of the samples induced adverse effects on the amphipod when testing sublethal and lethal end points. The toxicity of the samples in terms of survival rate was extremely high in two sites, in particular in samples taken downstream the Pilar industrial complex. The integration of a selection of physicochemical and toxicological parameters of the sediments by PCA allowed discriminating areas of the river basin according the type and intensity of their particular pollution condition.

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Effects of Salinity on Metal Uptake and Metallothionein mRNA Levels in the Organs of Tilapia Exposed to Cadmium, Copper, and Zinc Ions

Shek

Chan

2015

Arch Environ Contam Toxicol

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This study aimed to determine the effects of salinity on metal uptake and metallothionein (MT) mRNA levels in tilapia exposed to three metal ions. Male Oreochromis niloticus × O. aureus juveniles (hereafter, "tilapia") were exposed to various concentrations (100, 500, and 1 ppm) of metal ions (Cd(2+), Cu(2+) and Zn(2+)) in freshwater and water with two levels of salinity (10 and 20 ppt) for 7 days. Tests were then performed to investigate the effects of salinity on metal concentrations and MT mRNA induction in the test subjects' organs. Saline decreased cadmium (Cd) uptake and MT mRNA fold induction in various internal organs, but it did not enhance MT mRNA induction in the gills. Exposure to Cu(2+) caused greater copper (Cu) levels in the brains, intestines and livers, but Cu uptake in the intestines and kidneys occurred only at 10 ppm. MT mRNA induction caused by Cu(2+) was observed in various internal organs, but it occurred in the gills only at greater levels of salinity. Exposure at greater salinities also decreased zinc (Zn) uptake and MT mRNA induction in all organs except the gills. Although greater salinity decreased Cd and Zn uptake, the metal content in the water correlated with the MT mRNA levels in most of the organs, except for the intestines. In conclusion, metal accumulations in the livers and kidneys of tilapia correlated with MT mRNA levels. The levels of MT mRNA in the livers and kidneys of tilapia might therefore be used as biomarkers of exposure to Cd(2+), Cu(2+) and Zn(2+) in water of various salinities.

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Ecotoxicological study on sediments of Mai Po marshes, Hong Kong using organisms and biomarkers

Cited by 16 publications

References 44 publications

Cadmium, lead, and arsenic contamination in paddy soils of a mining area and their exposure effects on human HEPG2 and keratinocyte cell-lines

Cadmium, lead, and arsenic contamination in paddy soils of a mining area and their exposure effects on human HEPG2 and keratinocyte cell-lines

Physicochemical and ecotoxicological based assessment of bottom sediments from the Luján River basin, Buenos Aires, Argentina

Effects of Salinity on Metal Uptake and Metallothionein mRNA Levels in the Organs of Tilapia Exposed to Cadmium, Copper, and Zinc Ions

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