Ecotoxicological Impact of Sub-lethal Concentrations of Glyphosate–based Herbicide on Juvenile Clarias gariepinus

Ujowundu, C. O.; Koloseke, D; Uba, Nneamaka; Achilike, J; Ogbuagu, Henry D.; Ubuoh, E. A.

doi:10.9734/jammr/2017/34374

Cited by 3 publications

(1 citation statement)

References 28 publications

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“…Uproot is a commercially formulated glyphosate mix herbicide and a known terrestrial and aquatic contaminants [27][28][29]. This makes it very important and urgent to develop a therapy for sublethal and lethal exposure to Uproot-herbicide…”

Section: Discussionmentioning

confidence: 99%

Biochemical and liver histological changes in rats exposed to sub-lethal dose of Uproot-pesticide and the protective potentials of nutritional supplements

Ujowundu¹,

Isaac²,

Ntite³

et al. 2020

J Appl Biol Biotech

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This study determined the therapeutic potentials of vitamin C, glutathione, and garlic on the hepatic and histological changes induced by uproot-pesticide on albino Wistar rats. All animal groups (except normal control) received intraperitoneally 50 mg/kg body weight of uproot-pesticide (a commercially formulated glyphosate-based herbicide) on alternate days and daily oral administration (except Uproot control) of 20 mg/ kg body weight of glutathione, vitamin C, and garlic as nutritional supplements singly and in combination for 28 days. Liver function and oxidative stress parameters of the liver were determined using blood and liver samples. Histological studies were done on the liver tissue. The values obtained showed significant variation of measured parameters in Uproot control compared to groups administered nutritional supplements and the control. These variations indicated oxidative liver damage and significant therapeutic potential of the nutritional supplements. Other observed significant and non-significant changes were discussed.

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Section: Discussionmentioning

confidence: 99%

Biochemical and liver histological changes in rats exposed to sub-lethal dose of Uproot-pesticide and the protective potentials of nutritional supplements

Ujowundu¹,

Isaac²,

Ntite³

et al. 2020

J Appl Biol Biotech

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In vitro efficacy of emamectin benzoate and glyphosate against monogenean parasites from Colossoma macropomum

Baia,

Alves,

Malheiros

et al. 2024

Arq. Bras. Med. Vet. Zootec.

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This study investigated the in vitro efficacy of emamectin benzoate and glyphosate against monogeneans from Colossoma macropomum and tolerance of this species to these therapeutic drugs. In vitro assays demonstrated that concentrations of emamectin benzoate (12.5, 16.6, 20.8 and 25.0g/L) and glyphosate (2,000; 3,000; 4,000 and 5,000mg/L) were 100% effective against Anacanthorus spathulatus, Notozothecium janauachensis and Mymarothecium boegeri. The highest concentrations of emamectin benzoate (20.8 and 25.0g/L) were 100% effective after 30 minutes of exposure. For glyphosate, the highest concentrations were the most effective, and 4,000 and 5,000 mg/L immobilized 100% of parasites in 45 minutes and 30 minutes, respectively. Scanning electron microscopy revealed that the parasites exposed to 20.8 and 25.0g/L of emamectin benzoate and 5,000 mg/L of glyphosate presented integument covered with deeper wrinkles. Behavioral changes occurred in C. macropomum exposed to all concentrations of both drugs, were as mortality occurred following exposure to emamectin benzoate and glyphosate at 2.0,12,5 and 25.0g/L and 500, 1,000, 2,000, 3,000, 4,000 and 5,000mg/L, respectively. Low concentrations of emamectin benzoate and of glyphosate were tolerated by C. macropomum, but these concentrations may have not efficacy against infection of monogeneans.

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Chemoprotective Potentials of Selected Dietary Supplements in Glyphosate-based Herbicide-induced Nephrotoxicity and Dyslipidemia in Albino Wistar Rats

Ony¹,

Eberechukw²,

Nti³

et al. 2019

Asian J. of Biological Sciences

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Ecotoxicological Impact of Sub-lethal Concentrations of Glyphosate–based Herbicide on Juvenile Clarias gariepinus

Cited by 3 publications

References 28 publications

Biochemical and liver histological changes in rats exposed to sub-lethal dose of Uproot-pesticide and the protective potentials of nutritional supplements

Biochemical and liver histological changes in rats exposed to sub-lethal dose of Uproot-pesticide and the protective potentials of nutritional supplements

In vitro efficacy of emamectin benzoate and glyphosate against monogenean parasites from Colossoma macropomum

Chemoprotective Potentials of Selected Dietary Supplements in Glyphosate-based Herbicide-induced Nephrotoxicity and Dyslipidemia in Albino Wistar Rats

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