Echinacea for preventing and treating the common cold

Linde, Klaus; Barrett, Bruce; Bauer, Rudolf; Melchart, Dieter; Woelkart, Karin

doi:10.1002/14651858.cd000530.pub2

Cited by 123 publications

(82 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Previous studies showed to decrease the severity and reduce the duration of colds and upper respiratory infections, especially when Echinacea is taken early in the course of infection (33,34). A recent case-control study showed the favourable effect of Echinacea on gastrointestinal mucosal recovery in children with mucositis due to chemotherapy (35).…”

Section: Discussionmentioning

confidence: 99%

The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid

Doğan¹,

Ergül²,

Sarıkaya³

et al. 2014

BLL

View full text Add to dashboard Cite

Abstract:Background: Ulcerative colitis is a chronic infl ammatory condition of the colon, and reactive oxidative metabolites (ROMs) play an important role in its pathogenesis. Alternative therapies such as herbal remedies are increasingly being used in the treatment of ulcerative colitis for better clinical outcome of ulcerative colitis and less adverse effects. Echinacea has many features including antioxidant and wound-healing properties. Hence, the present study was undertaken to evaluate the protective effect of Echinacea spp. on experimental colitis model induced by acetic acid in Wistar albino rats. Methods: Acute colitis was induced by intrarectal administration of acetic acid. Rats were divided into four groups, namely control, Echinacea-administered, Echinacea-administered-colitis and colitis. Malondialdehyde and total antioxidant status were assayed in tissue samples. Histopathological evaluation was also performed. Results: Macroscopic and microscopic scores were signifi cantly higher in colitis group compared to control, Echinacea and Echinacea-colitis groups (p < 0.001). There was no signifi cant differences in respect of macroscopic and microscopic scores between control, Echinacea and Echinacea-colitis groups (p > 0.3, p > 0.22). Malondialdehyde levels were elevated in colitis group compared to other groups (p < 0.001). Total antioxidant status was signifi cantly higher in Echinacea group compared with other groups and also signifi cantly higher in Echinacea-colitis group compared with colitis group (p < 0.001, p < 0.001, respectively). Conclusion: Echinacea may possibly have some therapeutic usefulness in the management of ulcerative colitis (Tab. 2, Fig. 4, Ref. 35). Text in PDF www.elis.sk.

show abstract

Section: Discussionmentioning

confidence: 99%

The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid

Doğan¹,

Ergül²,

Sarıkaya³

et al. 2014

BLL

View full text Add to dashboard Cite

show abstract

“…Alprazolam, amiodarone, amlodipine, atorvastatin, bicalutamide, cilostazol, cimetidine, cyclosporine, fluoxetine, fluvoxamine, ginkgo, § isoniazid, nilotinib, oral contraceptives, ranitidine, ranolazine, tipranavir/ritonavir, zileuton Amprenavir, aprepitant, armodafinil, echinacea, § pioglitazone, prednisone, rufinamide 116 Randomized, double-blind, placebo-controlled trials showed no beneficial effects of unrefined echinacea or echinacea capsules on symptoms of common cold or rhinovirus infection compared to placebo. 117,118 Echinacea use has been reported to cause side effects such as nausea, dizziness and gastrointestinal upset.…”

Section: Weak Inducers (20-50% ↓ In Auc)mentioning

confidence: 99%

Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease

Sultan¹,

Maria²,

Ali³

et al. 2015

Journal of Patient-Centered Research and Reviews

View full text Add to dashboard Cite

“…In brief, the numerous randomized studies, systematic reviews and meta-analysis indicate that a likely benefit exists, albeit small, due to the pharmacological activity of Echinacea. [17][18][19] Unfortunately, certain controversy has been generated about these results. As Hart et al 20 discussed regarding the results obtained from three meta-analyses on the efficacy of Echinacea in the prevention and treatment of common cold, the methodology followed in a systematic review (search strategy, inclusion and exclusion criteria, data analysis, etc.)…”

Section: Assessment Of Pfs High and Low Intakesmentioning

confidence: 99%

Plant food supplement (PFS) market structure in EC Member States, methods and techniques for the assessment of individual PFS intake

et al. 2011

View full text Add to dashboard Cite

The popularity of herbal products, especially plant food supplements (PFS) and herbal medicine is on the rise in Europe and other parts of the world, with increased use in the general population as well as among specific subgroups encompassing children, women or those suffering from diseases such as cancer. The aim of this paper is to examine the PFS market structures in European Community (EC) Member States as well as to examine issues addressing methodologies and consumption data relating to PFS use in Europe. A revision of recent reports on market data, trends and main distribution channels, in addition an example of the consumption of PFS in Spain, is presented. An overview of the methods and administration techniques used to assess individual food consumption as a starting point, including their uses and limitations, as well as some examples of studies that collect Food Supplement (FS) information, including herbal/botanical/plant-derived products are also discussed. Additionally, the intake estimation process of food nutrients is described and used to propose the PFS ingredients intake estimation process. Nationally representative PFS consumption data is scarce in Europe. The majority of studies have been conducted in Scandinavia and the UK. However the heterogeneity of definitions, study design and objectives make it difficult to compare results and extrapolate conclusions.

show abstract

Echinacea for preventing and treating the common cold

Cited by 123 publications

References 42 publications

The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid

The antioxidant effect of Echinacea angustifolia and Echinacea purpurea in rat colitis model induced by acetic acid

Essentials of Herb-Drug Interactions in the Elderly With Cardiovascular Disease

Plant food supplement (PFS) market structure in EC Member States, methods and techniques for the assessment of individual PFS intake

Contact Info

Product

Resources

About