Eccrine porocarcinoma of the scalp

Ekmekçi, Sümeyye; Lebe, Banu

doi:10.5146/tjpath.2013.01169

Cited by 5 publications

(2 citation statements)

References 25 publications

(23 reference statements)

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“…The remaining 116 EPC cases of the head and neck from 90 studies were included in the meta‐analysis. The studies consist of 77 single case reports 7‐14,21,25‐93 and 13 case series with an average of three cases 20,23,24,94‐103 . Additionally, four EPC cases of the University Hospital of the Medical University of Vienna and Evangelical Hospital Vienna could be included in the meta‐analysis.…”

Section: Methodsmentioning

confidence: 99%

Eccrine porocarcinoma of the head and neck: Meta‐analysis of 120 cases

Janik

Liu

et al. 2020

Head & Neck

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Background The aim of the study is to analyze potential prognostic factors and to evaluate therapy strategies regarding clinical outcome in patients with eccrine porocarcinoma (EPC) of the head and neck. Methods One hundred and sixteen EPC cases from ninety studies and four authors' EPC cases were included in the meta‐analysis. Results At an average follow up of 20.48 months, the 3‐year overall survival and regional recurrence rate were 70.3% and 19.0%, respectively. Patients without surgical treatment had a significantly worse 3‐year overall survival. Mohs microscopic surgery led to significantly less occurrence of regional recurrences compared to wide excision. An ulcerating lesion, high mitotic activity, and lymphovascular invasion were significant prognostic factors. Conclusion Surgical resection is the cornerstone in the therapy of EPC and represents the therapeutic modality that offers the best chance of disease‐free survival. Due to the high probability of recurrence, close follow‐ups are strongly recommended.

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Section: Methodsmentioning

confidence: 99%

Eccrine porocarcinoma of the head and neck: Meta‐analysis of 120 cases

Janik

Liu

et al. 2020

Head & Neck

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“…Our case represents a rare clinical presentation that occurred on the scalp of a relatively young patient with an unexpected histopathologic finding of cytoplasmic eosinophilia. To date, only 16 cases of porocarcinoma have been reported on the scalp ( Ekmekcı and Lebe, 2013 , Grimme et al, 1999 , Kim et al, 2012 , Kose et al, 2006 , Matloub et al, 1988 , Permi et al, 2011 , Puttick et al, 1986 , Ritter et al, 1999 , Shaw et al, 1982 , Sigal et al, 1997 , Tarkhan and Domingo, 1985 , Urso et al, 2001 , Vessels et al, 2011 ). Of these 16 cases, three of the porocarcinomas metastasized, two demonstrated a recurrent local invasion, and one had an intracranial extension.…”

Section: Discussionmentioning

confidence: 99%

Eosinophilic variant of eccrine porocarcinoma of the scalp: Case report and review of the literature

Horwich

Finch

Ibrahimi

et al. 2017

International Journal of Women's Dermatology

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Porocarcinoma is a rare malignant neoplasm of the acrosyringium with metastatic potential that most commonly presents on the acral skin in older adults (mean age = 72 years). We present the case of a 43-year-old woman who developed a rapidly growing de novo porocarcinoma on the scalp with an unusual oncocytic appearance. The tumor consisted of benign eccrine poroma that arose from the epidermis and broad pushing borders with minimal cytological atypia but ample eosinophilic cytoplasm with numerous mitotic figures. Although some tumors may appear deceptively bland, the histologic recognition of pushing/infiltrative borders and mitotic figures are helpful to make the appropriate diagnosis of carcinoma. This lesion was treated with Mohs micrographic surgery and the patient remained free of recurrence after more than 2 years. It is important to recognize the eosinophilic variants of eccrine porocarcinoma because it can histologically mimic a squamous cell carcinoma.

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