Eccrine Angiomatous Hamartoma Mimicking a Traumatic Hemorrhage

Abstract

Eccrine angiomatous hamartoma (EAH) is a rare benign disease that is characterized by an abnormal proliferation of eccrine glands and vascular elements. It is generally congenital, but it can appear before puberty. It usually presents as a single plaque or nodule, but multiple patch-like lesions are also possible. EAH is mostly asymptomatic, but it is sometimes associated with pain or hyperhidrosis. It generally does not require aggressive treatment, but the lesion can be excised due to pain, enlargement and cosmetic reasons. A 3-week-old Korean female presented with a hemorrhagic skin lesion on the right foot since birth. There was no specific birth history. The lesion first appeared on the third toe of the right foot and quickly spread to almost half of the right foot. Histopathology examination revealed acanthosis in the epidermis and a proliferation of eccrine ducts, glands and capillaries. The eccrine glands were immunohistochemically-positive for carcinoembryonic antigen.

Eccrine Angiomatous Hamartoma: A Review of Ten Cases

“…A previous article reviewed the characteristics of 15 Korean cases of EAH3. The lesions were mostly congenital (9/14, 64.2%), and although hyperhidrosis was frequent (10/15, 66.7%), they could be asymptomatic (5/15, 33.3%) or painful (6/15, 40.0%).…”