Eating disorders in adolescent girls with insulin-dependent diabetes mellitus: a population-based case-control study

Abstract

In this study the prevalence of eating disorders in a population-based cohort of 89 female patients with type 1 diabetes, 14-18 y of age, was compared with that in age-matched healthy controls. Of all diabetic girls in the study area, 92% participated in the study. The majority were treated with multiple insulin injections and the mean HbA1c of the participants was 8.4%. On average, diabetic girls were 6.8 kg heavier than the controls. A two-stage design was used. The first consisted of a validated self-report questionnaire, the Eating Disorder Inventory (EDI). Girls who had high scores were then interviewed about eating habits and mental health using a semistructured interview, the BAB-T (Assessment of Anorexia-Bulimia - Teenager version). No cases of anorexia or bulimia nervosa were found, but 15 diabetic patients (16.9%) compared with 2 control girls (2.2%), p<0.01, had disturbed eating behaviour according to the questionnaire. In 6 of these 15 diabetic girls an eating disorder was confirmed at the interview, mainly binge eating and self-induced vomiting. None of the control girls showed an eating disorder. Overweight diabetic girls scored higher on EDI than non-overweight diabetic girls (chi2 = 4.9; p = 0.038). No relationships were found between EDI scores and metabolic control (HbA1c), dose of insulin, frequency of hypoglycaemia or diabetic ketoacidosis.

Metformin as additional therapy in adolescents with poorly controlled type 1 diabetes: randomised placebo-controlled trial with aspects on insulin sensitivity

“…The non-participating adolescents did not differ from those who did participate regarding age, daily dosage of insulin, body mass index (BMI) or HbA 1c . In the other centres, which had a comparable number of patients, treatment guidelines and mean HbA 1c (14), the participation rates were lower due to the need for travelling by car or train to the centre in Ö rebro.…”

Eating Disorders in Adolescent Girls and Young Adult Women With Type 1 Diabetes

“…7,29 All but the study by Jones and colleagues 7 had small sample sizes and consequently insufficient power to demonstrate that a difference of this magnitude was statistically significant.…”

“…7,23- 29 The outcomes of these studies appear to depend heavily on the sample studied, the methodology employed, and the diagnostic criteria for eating disorders applied.…”

“…8,[22][23][24]47,48 Finally, studies using DSM-IV criteria have reported the prevalence of eating disorders to range from 7-11% of adolescent and young adult females with type 1 diabetes. 7,29,49 In all of the studies employing DSM-IV criteria, bulimia nervosa and ED-NOS are much more common than anorexia nervosa. This finding is not surprising, given that bulimia nervosa and its variants are more common than anorexia nervosa in the general population.…”

Diabetes e transtornos alimentares: uma associação de alto risco

“…[3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] Parte da literatura parece inconclusiva quanto à verificação da prevalência da comorbidade. Alguns estudos controlados com mulheres jovens diabéticas do tipo 1 não encontraram qualquer diferença de prevalência de transtornos alimentares entre portadoras ou não de DM.…”