Ease of oral administration and owner-perceived acceptability of triglyceride oil, dissolving thin film strip, and gelatin capsule formulations to healthy cats

Traas, Anne M.; Fleck, Thomas J.; Ellings, Andrea; Mahabir, Sean P.; Stuebner, Kathy; Brown, Dorothy Cimino; Durso, Dana; DiGregorio, Michael; Bode, Lora; Kievit, Kelly I.; McCall, Robert B.

doi:10.2460/ajvr.71.6.610

Cited by 8 publications

(5 citation statements)

References 4 publications

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“…Administration of AM agents used for dogs was principally by oral tablet (81 per cent), whereas the majority of AM agents for cats were administered via the injectable method (55 per cent). This likely reflects general differences in methods of administering medicines between the species, with oral tablets being perceived as more difficult to effectively administer in cats (Traas and others 2010). Dogs received proportionally more aminopenicillin types (54 per cent v 46 per cent) and nitromidazoles (11 per cent v 5 per cent) than cats.…”

Section: Discussionmentioning

confidence: 99%

Characterisation of antimicrobial usage in cats and dogs attending UK primary care companion animal veterinary practices

et al. 2016

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(200 words)There is scant evidence describing antimicrobial usage in companion animal primary-care veterinary practices in the UK. The use of antimicrobials in dogs and cats was quantified using data extracted from 374 veterinary practices participating in VetCompass. The frequency and quantity of systemic antimicrobial usage was described.Overall, 25% of 963,463 dogs and 21% of 594,812 cats seen at veterinary practices received at least one antimicrobial over the two-year period , and 42% of these animals were given repeated antimicrobials. The main agents used were amino-penicillin-types and cephalosporins. Of the AM events, 60% in dogs and 81% in cats were antimicrobials classified as critically important (CIAs) to human health by the World Health Organisation. CIAs of highest importance (fluoroquinolones, macrolides, third-generation cephalosporins) accounted for just over 6% and 34% of antimicrobials in dogs and cats, respectively. The total quantity of antimicrobials used within the study population was estimated to be 1473Kg for dogs and 58Kg for cats.This study has identified a high frequency of usage of antimicrobials in companion animal practice and for certain agents classified as of critical importance in human medicine. The study highlights the usefulness of veterinary practice electronic health records for studying AM usage.2

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Section: Discussionmentioning

confidence: 99%

Characterisation of antimicrobial usage in cats and dogs attending UK primary care companion animal veterinary practices

et al. 2016

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“…On the other hand, several field trials have been conducted in the last few years in cats (Litster and others 2007, Gunew and others 2008, Traas and others 2010, Morton and others 2011, Khor and others 2012). In these studies, the owners evaluated the acceptability of pharmaceutical drugs via questionnaires, a rating of the ease of administration on a 10‐cm visual analogue scale, a rating of overall acceptability of formulations from their own perspective and their overall perception of acceptability to their cat, or via the ease of administration of the tested formulations.…”

Section: Discussionmentioning

confidence: 99%

Palatability evaluation study of a new oral formulation of marbofloxacin in cats

Cron¹,

Zemirline²,

Beranger³

et al. 2014

Veterinary Record

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At a time when antimicrobial resistance is a global concern in human and animal health, it is of primary importance to draw attention to the problem of compliance with antibiotic therapy in animals hard to medicate such as cats. Resistance may develop because of poor patient compliance with the prescribed course of antibiotic therapy. Increasing palatability might enhance administration compliance. We assessed the acceptability of EFEX tablets, a new oral marbofloxacin formulation for cats. The objective of this study was to compare EFEX to two commercial formulations of marbofloxacin: MARBOCYL P palatable tablets and MARBOCYL Vet tablets. Acceptance tests were run in experimental conditions in 24 cats to compare the spontaneous intake and full consumption of the three pharmaceutical products. The results indicated that EFEX was more palatable than MARBOCYL Vet (0.001

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“…It was evaluated the overall owner-perceived acceptability and the easiness administration of an orodispersible film compared with gelatin capsules in cats. Although there were no significant differences in the general acceptability of the owners, it was shown that the orodispersible films facilitated significantly the administration of the medication [149,150]. Currently, few companies have developed oral films applied to this segment, and the available products are scarce and limited to OTC products based on blends of herbal extracts [151,152].…”

Section: Market Outlookmentioning

confidence: 99%

Oral films: Current status and future perspectives II — Intellectual property, technologies and market needs

Borges

Silva²,

Coelho

et al. 2015

Journal of Controlled Release

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Ease of oral administration and owner-perceived acceptability of triglyceride oil, dissolving thin film strip, and gelatin capsule formulations to healthy cats

Cited by 8 publications

References 4 publications

Characterisation of antimicrobial usage in cats and dogs attending UK primary care companion animal veterinary practices

Characterisation of antimicrobial usage in cats and dogs attending UK primary care companion animal veterinary practices

Palatability evaluation study of a new oral formulation of marbofloxacin in cats

Oral films: Current status and future perspectives II — Intellectual property, technologies and market needs

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