EARLY STUDY THE POTENCY OF TURMERIC (Curcuma domestica Val.) AS IMMUNOSTIMULATOR FOR LAYERS CHICKENS AGAINST AVIAN INFLUENZA (AI) VACCINE

Abstract

Abstract-This study was conducted to know the effect of turmeric as immunomodulator in layer chicken against Avian influenza vaccine. This research used DOC that were given turmeric ethanol extract 50% concentration at day 8 until day 21, and Avian influenza vaccine was given at day 15. The bloods sample were collected at day 7, 14, and 21 at brachial vein. It was an experimental research and data were analyzed using t test paired sample. The result of total heterophils before AI vaccine was given showed an increased significant effect (p<0.05) (12.6563 ± 4.60) %, and after vaccine was (19.0000 ± 9.22) %. The results of total basophils before AI was given showed there was no significant effect (p>0.05) (2.9688 ± 1.96) %, and after vaccined was (3.2813 ± 1.76) %. It can be concluded that turmeric has an immunomodulatory effect.

Pengaruh Ekstrak Kunyit (Curcuma domestica Val) Terhadap Berat Badan, Jumlah Eosinofil dan Basofil Ayam Petelur yang Diinfeksi Salmonella pullorum

“…Penelitian yang dilakukan oleh Widhowati et al (2017) juga menunjukkan bahwa pemberian kunyit sebagai suplemen makanan untuk ayam petelur telah meningkatkan jumlah heterofil dan basofil serta berefek imunostimulan terhadap vaksin flu burung. Kurkuminoid memodulasi sistem imun dengan meningkatkan poliferasi sel yang berperan dalam imunitas yaitu sel leukosit.…”

Herbal Medicine Additives as Powerful Agents to Control and Prevent Avian Influenza Virus in Poultry – A Review

“…Since long time herbal and traditional plants had been used to prevent and control many diseases and health problems on a small scale such as in heavy metals toxicity (Khafaga et al, 2019 a, b), ectoparasites (Abbas et al, 2018), reproductive and renal toxicity (Khafaga and Bayad, 2016 a, b), heat stress (Khafaga et al, 2019 a, b), and viral disease (Oyuntsetseg et al, 2014;Mahmood et al, 2018;Sun et al, 2018). People around the world are now aware of the advantageous use of natural derived products such as microalgae (Subhani et al, 2018;Abdelnour et al, 2019;Abd El-Hack et al, 2015, 2016, 2018, 2019, rare earth elements (Abdelnour et al, 2019), and botanicals (Mahmood et al, 2018;Shah et al, 2018) over synthetic drugs and chemicals in terms of lower cost, toxicity and adverse effects and very low resistance (Karimi et al, 2015). As a result, herbal medicine is gaining more importance in the anti-influenza research owing to their widespread availability and easy application in the diet (Abd El-Hamid et al, 2018).…”