Early stroke case-fatality rates in three hospital registries in the Northeast and Southeast of Brazil

Fernandes, Tiótrefis Gomes; Goulart, Alessandra Carvalho; Campos, Tânia; Lucena, Neide María Gomes de; Freitas, Karen L. A.; Trevisan, Cláudia Morais; Lotufo, Paulo A.

doi:10.1590/s0004-282x2012001100009

Cited by 14 publications

(14 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In two other crosssectional, hospital-based studies conducted during 2001 and 2006-2008 in Qom, a well-known religious city of Iran, the casefatality rate within the first month was reported at 24.6% during 2001, and at 15.3% from 2006 to 2008. Although, these figures showed an apparently declining rate over time in this region, but were still greater than reported ones from western countries and lesser than other developing countries [8][9][10][11][12].…”

Section: Introductioncontrasting

confidence: 60%

Case-Fatality and Disability of Patients with Stroke in Iran

A¹

2015

JNSK

View full text Add to dashboard Cite

show abstract

Section: Introductioncontrasting

confidence: 60%

Case-Fatality and Disability of Patients with Stroke in Iran

A¹

2015

JNSK

View full text Add to dashboard Cite

show abstract

“…It is suggested that the low hospital assistance of these FU may be the source of such stability or even low quality of the SIH/ SUS in the state health system. In general, Fernandes et al 37 verified the non-existence of mortality by stroke among hospitals in Northeast and Southeast Brazil.…”

mentioning

confidence: 96%

Hospitalização por acidente vascular encefálico isquêmico no Brasil: estudo ecológico sobre possível impacto do Hiperdia

Lopes

Sanchis

Medeiros

et al. 2016

Rev. bras. epidemiol.

View full text Add to dashboard Cite

Objective:The study evaluated the trend of hospitalization for ischemic stroke (HIS) and its hospital mortality in Brazil over the last 15 years as well as the impact of the Hiperdia program in this scenario. Methods: An ecological study was designed with analytical approach and data collected in the Hospital Admission System on episodes of stroke, over the years 1998 to 2012. All data were stratified by sex and age, creating an indicator for HIS and proportion of hospital mortality. To estimate the trend of the data a polynomial curve fitting was created; and the Generalized Linear Model was applied to investigate the impact of Hiperdia on the endpoint HIS and hospital mortality. We adopted a 5% significance level to minimize an error type I. Results: We observed a reduction of HIS from 37.57/10 5 inhabitants in 1998 to 2001 to 10.33/10 5 inhabitants in 2002 to 2005, declining 73.64%. The reduction occurred in both sexes and for all age groups. The mortality rate of ischemic stroke also declined in Brazil since 2002, in both men and women, therefore in less than 3%; and only in the groups aged between 0 and 14 and above 80 years, we did not detect trend. Conclusion: Therefore, the decline of HIS temporally coincided with the implementation of Hiperdia in 2002 and this trend continues today.

show abstract

“…This cohort was the first one to demonstrate the prognosis value of multimorbidity using CCI in long-term survival in a stroke cohort in Latin America. EMMA study is an ongoing stroke cohort, which demonstrated several stroke outcomes mentioned in previous publications in the last decade [10,23,29,30,31,32]. The study population in EMMA comes from a low-income area with poor public health support in the city of São Paulo located in Brazil.…”

Section: Discussionmentioning

confidence: 99%

Multimorbidities Are Associated to Lower Survival in Ischaemic Stroke: Results from a Brazilian Stroke Cohort (EMMA Study)

Castro¹,

Alencar²,

Benseñor³

et al. 2017

Cerebrovasc Dis

Self Cite

View full text Add to dashboard Cite

Background: Stroke prognosis is related to the multimorbidity profile. Moreover, performing an individual evaluation of most common cerebrovascular risk factors (CVRF) not always identifies patients with poor prognosis. Thus, we decided to evaluate multimorbidity profile, focusing on the Charlson Comorbidity Index (CCI) validated by Goldstein for ischaemic stroke (IS) patients, a score that measures a burden of comorbidities and its related mortality in the long-term survival of the EMMA Study (Study of Stroke Mortality and Morbidity). Methods: Nine hundred fifty-nine individuals (median age 70 years) had validated data on the diagnosis of IS, main CVRF and clinical comorbidities pre index event such as atrial fibrillation (AF), stroke recurrence, diabetes, hypertension, heart failure and cancer. CCI modified by Goldstein was calculated, which includes 17 clinical conditions with scores ranging from 1 to 6 (0-31 points). Survival analyses were performed by Kaplan-Meier curves and Cox logistic regression models (cumulative hazard ratio [HR] with [95% CI]) for all-cause mortality at 180 days, and every 3 years up to 9-year follow-up. Mortality analyzes were performed by CCI categorized according to weight added to comorbidities (Reference group: zero, moderate: 1, severe: 2 and very severe: ≥3 points). We also tested the modification effect of AF and stroke recurrence including these conditions in the CCI. Results: The overall survival rate was 47% (508 deaths/959). The worst survival (577, 95% CI 381-773 days) and the highest risk of death after stroke were observed in the very severe CCI group (HR 3.18; 95% CI 2.16-4.69) up to 9 years. The inclusion of previous AF and stroke in the CCI slightly increased the risk of death for very severe CCI (HR 3.27; 95% CI 2.07-5.18). Conclusions: A high burden of comorbidities represented an independent predictor of poor prognosis increasing the risk of dying by 2 to 3 times among IS up to 9 years in the EMMA study. The inclusion of other CVRF such as AF and stroke recurrence slightly modified all-cause mortality risk.

show abstract

Early stroke case-fatality rates in three hospital registries in the Northeast and Southeast of Brazil

Cited by 14 publications

References 12 publications

Case-Fatality and Disability of Patients with Stroke in Iran

Case-Fatality and Disability of Patients with Stroke in Iran

Hospitalização por acidente vascular encefálico isquêmico no Brasil: estudo ecológico sobre possível impacto do Hiperdia

Multimorbidities Are Associated to Lower Survival in Ischaemic Stroke: Results from a Brazilian Stroke Cohort (EMMA Study)

Contact Info

Product

Resources

About