Early outcomes of laparoscopic sleeve gastrectomy in a multiethnic Asian cohort

Ching, Siok Siong; Cheng, Anton; Kong, Lucy W. C.; Lomanto, Davide; So, Jimmy Bok Yan; Shabbir, Asim

doi:10.1016/j.soard.2015.05.009

Cited by 11 publications

(8 citation statements)

References 35 publications

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“…Medications for hypertension and T2DM were reduced or removed from the patient after surgery, before hospital discharge 31 . The same result was obtained by Ching et al 11 with 60% remission rate for T2DM.…”

Section: Resultssupporting

confidence: 87%

The Role of the Sleeve Gastrectomy and the Management of Type 2 Diabetes

Fuchs¹,

Loureiro²,

Both

et al. 2017

ABCD, arq. bras. cir. dig.

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Background : Currently, bariatric surgery has promoted weight loss and improved glycemic control in obese patients through different techniques, including vertical sleeve gastrectomy. Aim : Present and update the different vertical sleeve gastrectomy ways of action, both in the treatment of obesity and diabetes, approaching its potential effect on gastrointestinal physiology, as well as the benefits achieved by this manipulation. Methods : Pubmed database search was used crossing the headings: obesity, type 2 diabetes and sleeve gastrectomy. Results : Published data have shown that short-term weight loss tends to be higher in patients undergoing vertical sleeve gastrectomy compared to Roux-en-Y gastric bypass. In relation to glycemic control, the procedure demonstrated remission of diabetes in up to 60% after one year of surgery. After three years, however, differences in remission rate between surgical and clinical group was not observed, questioning the durability of the technical in a long-term. Conclusion : Despite showing good results, both in the weight loss and co-morbidities, conflicting results reinforce the need for more studies to prove the efficiency of the vertical sleeve gastrectomy as well as to understand its action about the molecular mechanisms involved in the disease.

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Section: Resultssupporting

confidence: 87%

The Role of the Sleeve Gastrectomy and the Management of Type 2 Diabetes

Fuchs¹,

Loureiro²,

Both

et al. 2017

ABCD, arq. bras. cir. dig.

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show abstract

“…In our study, the overall remission rate among the 189 patients with T2DM was 80.3%, which is comparable to that in literature . We also found that LSG is an effective bariatric surgery with a high remission rate for T2DM (82.2%) and a % EWL of 61.2% at 1 year in a multi‐ethnic Asian population.…”

Section: Discussionsupporting

confidence: 87%

“…Current available evidence is predominantly Western‐based reports. In Asia, early outcomes of laparoscopic sleeve gastrectomy have been reported to be safe and effective in achieving significant weight loss . Considering the growing number of metabolic surgeries in Asia, we have attempted to provide a regional perspective on 5‐year long‐term clinical outcomes post bariatric surgery in Singapore.…”

Section: Introductionmentioning

confidence: 99%

Five‐year long‐term clinical outcome after bariatric metabolic surgery: A multi‐ethnic Asian population in Singapore

Toh

Chan

Eng

et al. 2018

Diabetes Obesity Metabolism

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Bariatric surgery is an effective treatment for morbid obesity and its metabolic related comorbidities; type 2 diabetes, hypertension and hyperlipidaemia. However, the literature is scarce regarding the long-term outcome after bariatric surgery, especially among multi-ethnic Asian populations. Considering the growing number of bariatric metabolic surgeries in Asia, we have attempted to provide a regional perspective on 5-year long-term clinical outcomes post bariatric surgery in Singapore. Between 2010 and 2016, all bariatric operative cases were included, and these comprised: laparoscopic sleeve gastrectomy (LSG), 393; laparoscopic Roux-En-Y gastric bypass (RYGB), 125; laparoscopic mini-gastric bypass (MGB), 43. The primary outcome measure was the percentage of excess weight loss (% EWL) at 6 months, 1, 2, 3, 4 and 5 years, with % remission of type 2 diabetes mellitus (T2DM) at 1 year following LSG (49.7%, 61.2%, 56.1%, 47.8%, 40.8% and 47.3%; 82.2%), RYGB (60.2%, 62.1%, 57.6%, 50.1%, 48.7% and 47.7%; 86.9%) and MGB (58%, 68.1%, 62.7%, 66.2%, 64.0%, 65.2%; 71.9%). In conclusion, MGB and RYGB showed the greatest % EWL at 5 years and are recommended for moderate T2DM. LSG is an effective bariatric operation with a high % EWL up to 2 years, and a high remission rate of mild T2DM. The remission rate of T2DM was equally high in all 3 surgical groups, independent of ethnic differences.

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“…Medications for T2DM and hypertension were decrease or withdrawn for those undergoing bariatric surgery, as early as prior to hospital discharge (Tritsch et al, 2015). In line with this, Ching et al (2016) found a 60% remission rate of T2DM after LSG that did not correlate with weight loss.…”

Section: Parasympathetic Nervous System and Laparoscopic Sleeve Gastrectomymentioning

confidence: 70%

Role of the Autonomic Nervous System in Mechanism of Energy and Glucose Regulation Post Bariatric Surgery

Wang

Mokadem

2021

Front. Neurosci.

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Even though lifestyle changes are the mainstay approach to address obesity, Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are the most effective and durable treatments facing this pandemic and its associated metabolic conditions. The traditional classifications of bariatric surgeries labeled them as “restrictive,” “malabsorptive,” or “mixed” types of procedures depending on the anatomical rearrangement of each one of them. This conventional categorization of bariatric surgeries assumed that the “restrictive” procedures induce their weight loss and metabolic effects by reducing gastric content and therefore having a smaller reservoir. Similarly, the “malabsorptive” procedures were thought to induce their main energy homeostatic effects from fecal calorie loss due to intestinal malabsorption. Observational data from human subjects and several studies from rodent models of bariatric surgery showed that neither of those concepts is completely true, at least in explaining the multiple metabolic changes and the alteration in energy balance that those two surgeries induce. Rather, neuro-hormonal mechanisms have been postulated to underly the physiologic effects of those two most performed bariatric procedures. In this review, we go over the role the autonomic nervous system plays- through its parasympathetic and sympathetic branches- in regulating weight balance and glucose homeostasis after SG and RYGB.

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Early outcomes of laparoscopic sleeve gastrectomy in a multiethnic Asian cohort

Cited by 11 publications

References 35 publications

The Role of the Sleeve Gastrectomy and the Management of Type 2 Diabetes

The Role of the Sleeve Gastrectomy and the Management of Type 2 Diabetes

Five‐year long‐term clinical outcome after bariatric metabolic surgery: A multi‐ethnic Asian population in Singapore

Role of the Autonomic Nervous System in Mechanism of Energy and Glucose Regulation Post Bariatric Surgery

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