Early onset, severe fetal growth restriction with absent or reversed end‐diastolic flow velocity waveform in the umbilical artery: Perinatal and long‐term outcomes

Abstract

The overall perinatal survival rate for pregnancies complicated by early onset, severe growth restriction with an EFW of < 501 g and AREDF is low. When delivery occurs for fetal indications, the majority of these women require classical CS. Short-term neonatal morbidity is high though none of the survivors had cerebral palsy.

The influence of mode of birth on neonatal survival and maternal outcomes at extreme prematurity: A retrospective cohort study

“…The rate of classical CS in our cohort is higher than that reported in 1997 from an Australian tertiary referral institution: 56% in our cohort compared with 20% at 24 weeks . This may reflect different definitions, case characteristics and/or clinician biases between the centres, but more likely reflects a change in clinical practice given the overall CS rate of 18% at that time at that institute. There was no increased maternal morbidity following classical incision in our cohort.…”

Sildenafil citrate therapy for severe early-onset intrauterine growth restriction

“…Complicating approximately 0.2% of pregnancies, severe early‐onset intrauterine growth restriction (IUGR) increases the risk of perinatal morbidity and mortality, particularly as a result of iatrogenic premature delivery 1 . Survival rates for severely growth‐restricted fetuses very remote from term (<28 weeks of gestation) are dismal 1,2 . Following supportive data from rat and guinea pig models of IUGR, Wareing et al 3 .…”

Neurodevelopmental and Somatic Growth Outcomes of Premature IUGR Newborns with Absent or Reversed End-diastolic Flow on Umblical Artery Doppler

“…Petersen ve ark. (23) çalışmasında, AREDF ve REDF'li olgularda tanı ve doğurtulma yaşını ortalama 4 gün olarak bildirmişlerdir. Diğer yandan bu olgularda önerilen doğurtulma yaşının 30 hafta ve üzeri olmasının morbiditeyi olumlu etkilemesi (24) bizim olgularımızda da söz konusu olmuştur.…”