Early-Onset Cancers in Adults: A Review of Epidemiology, Supportive Care Needs and Future Research Priorities

Hamilton, Ashleigh C.; Donnelly, David; Fitzpatrick, Deirdre; Coleman, Helen

doi:10.3390/cancers14164021

Cited by 12 publications

(9 citation statements)

References 73 publications

(74 reference statements)

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“…In addition, the disease and treatments used can leave patients with sequelae that require health systems to provide appropriate resources for their care. 3 , 25 …”

Section: Discussionmentioning

confidence: 99%

Increasing Annual Cancer Incidence in Patients Age 20-49 Years: A Real-Data Study

Ribelles,

Pascual,

Galvez-Carvajal

et al. 2024

JCO Glob Oncol

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PURPOSE Data from population-based studies have shown an increased incidence of certain types of neoplasms in patients younger than 50 years (early-onset cancer [EOC]); however, little information is derived from other real-world data sources. In a nonpopulation registry, we analyzed changes in the incidence of several neoplasms in successive generations. METHODS This cross-sectional study included all patients with a cancer diagnosis registered in one university hospital in Málaga, Spain, between 1998 and 2021, and 18 neoplasms were analyzed. For each neoplasm, the proportion of patients younger than 50 years and age 50 years and older (late-onset cancer [LOC]) of the total number of patients diagnosed each year was determined. In addition, the age limit was lowered to 45-40 years. Changes in these proportions between each year and the following year were assessed by calculating the annual percentage change (APC), and a final assessment of these changes was performed by determining the average APC (AAPC). RESULTS Of the 24,596 patients, 5,466 (22.2%) had EOC, and 19,130 (77.8%) had LOC. The incidence of all tumors increased throughout the study period in both age groups. The AAPC increase was higher in patients with EOC than in those with LOC for the following neoplasms: head and neck (6.1% v 4.6%), colon (11.0% v 8.2%), testicular (16.3% v –13.1%), non-Hodgkin lymphoma (8.4% v 5.9%), rectum (16.1% v 6.8%), kidney (27.8% v 20.1%), and sarcoma (43.4% v 28.6%). This increase was confirmed in patients younger than 45 years and 40 years. CONCLUSION Our results are consistent with the data published for most tumor sites analyzed. This global public health problem requires the utmost attention to decrease excess cancer in young patients.

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“…In addition, the disease and treatments used can leave patients with sequelae that require health systems to provide appropriate resources for their care. 3 , 25 …”

Section: Discussionmentioning

confidence: 99%

Increasing Annual Cancer Incidence in Patients Age 20-49 Years: A Real-Data Study

Ribelles,

Pascual,

Galvez-Carvajal

et al. 2024

JCO Glob Oncol

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“…As a result of these gaps, delays in the diagnostic process are common [ 24 ]. To address this challenge, it is necessary to promote the collection of family history (CRC and polyps) in primary care, especially amongst younger adults, to better inform screening and referral for risk assessment [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Understanding Colorectal Cancer Patient Experiences with Family Practitioners in Canada

Mksyartinian,

Mohammad,

Wildgoose

et al. 2024

Current Oncology

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Despite ongoing screening efforts, colorectal cancer (CRC) remains a leading cause of death in Canada. The aim of this study was to better understand the experiences of Canadian CRC patients with their family practitioners (FPs) during and after their CRC diagnosis. Patient-reported data were collected through an online questionnaire to understand their CRC diagnosis experiences and identify potential gaps in care. Various factors contributing to challenges throughout a patient’s CRC diagnosis (e.g., delayed CRC diagnosis) were determined using descriptive, qualitative, and inferential analyses. These factors could be targeted to optimize CRC care. This study found that 40.6% of the 175 respondents were unaware of at least one of the following aspects of CRC prior to their diagnosis: early-age onset (EAO), symptoms, and screening procedures. While 84.6% had access to a family physician (FP) before their diagnosis, only 17.7% were diagnosed by FPs. Higher proportions of younger individuals experienced misdiagnoses and felt dismissed compared to older individuals. Only half felt fully informed about their diagnosis when it was explained to them by their FP, while 53.1% had their diagnosis explained in plain language. Transitioning towards patient-centred care would promote pre-diagnosis CRC awareness, address differences in management of CRC care (e.g., dismissal and support), and accommodate for age and health-literacy-related disparities, thereby improving CRC care pathways for patients. Future research should investigate FPs experiences in detecting CRC cases to develop educational resources and recommendations, enhancing early detection and improving patient outcomes (1).

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“…Similarly, Martinez et al (2019) found that clinical distress related to unmet psychological needs affects one in four women. Focus groups, Social media can be used for patient support, advocacy, and information sharing [19]. Also, participants identified information needs as critical needs.…”

Section: Discussionmentioning

confidence: 99%

Supportive Care Needs of Jordanian Women Undergoing Breast Cancer Treatments

Al-Husban,

Maabreh

2023

Advances in Health Sciences Research

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Living with breast cancer and experiencing a wide range of issues necessitates supportive care (SC). SC provides the necessary services for those affected by cancer to meet their physical, psychological, informational, practical, and spiritual needs. Therefore, this study's objectives were to identify the SCN of women undergoing breast cancer treatments and identify the predictors of SCN. A descriptive quantitative design was used using a convenience sample of 289 women with breast cancer drawn from the two largest cancer centers in Amman city. SCNs were measured using the Supportive Care Needs Survey Short Form (SCNS-SF -34). The reported needs were mainly within the following domains: informational (Mean, 34.07, SD = 8.91), physical (Mean = 16.85, SD = 4.74, and psychological (Mean = 28.49, SD = 7.20). Results also showed that SCN was influenced by the participants' education (R = 0.395), stage of illness (R2 = 0.156), and functional status (R2 = 0.129), produced at (F = 10.73 and P ≤ .001). It indicated that 16% of the variance in the needs of women with breast cancer could be predicted by stage, education, and the functional status of the women. In conclusion, a routine and systematic assessment of the SCN, social support, available resources such as trained clinical nurse specialists, and access to information is recommended to provide appropriate support.

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Early-Onset Cancers in Adults: A Review of Epidemiology, Supportive Care Needs and Future Research Priorities

Cited by 12 publications

References 73 publications

Increasing Annual Cancer Incidence in Patients Age 20-49 Years: A Real-Data Study

Increasing Annual Cancer Incidence in Patients Age 20-49 Years: A Real-Data Study

Understanding Colorectal Cancer Patient Experiences with Family Practitioners in Canada

Supportive Care Needs of Jordanian Women Undergoing Breast Cancer Treatments

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