Early Nephrologic Consultation After Acute Kidney Injury

Puher, Stefanie L.; Bucaloiu, Ion D.; Perkins, Robert M.

doi:10.1053/j.ajkd.2011.04.013

Cited by 2 publications

(1 citation statement)

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“…Acute kidney injury (AKI) is a prevalent complication in critically ill patients, which results in long length of intensive care unit (ICU) stay, increased morbidity and mortality, and high risk of chronic kidney disease (CKD) and endstage renal disease (ESRD) [1,2]. Emerging evidence has demonstrated that early screening and managing the risk factors associated with AKI prevent in-hospital mortality of critical patients [3,4]. Therefore, it is necessary to identify economic and reliable clinical indicators that can outperform or add significant value to the existing conventional score system for ICU patients with AKI.…”

Section: Introductionmentioning

confidence: 99%

Prognostic value of fibrinogen to albumin ratios among critically ill patients with acute kidney injury

Xia

Yao

et al. 2021

Intern Emerg Med

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Fibrinogen to albumin ratios (FAR) have shown to be a promising prognostic factor for improving the predictive accuracy in various diseases. This study explores FAR's prognostic significance in critically ill patients with acute kidney injury (AKI). All clinical data were extracted from the Multiparameter Intelligent Monitoring in Intensive Care Database III version 1.4. All patients were divided into four groups based on FAR quartiles. The primary endpoint was in-hospital mortality. A generalized additive model was applied to explore a nonlinear association between FAR and in-hospital mortality. The Cox proportional hazards models were used to determine the association between FAR and in-hospital mortality. A total of 5001 eligible subjects were enrolled. Multivariate analysis demonstrated that higher FAR was an independent predictor of in-hospital mortality after adjusting for potential confounders (HR, 95% CI 1.23, 1.03–1.48, P = 0.025). A nonlinear relationship between FAR and in-hospital mortality was observed. FAR may serve as a potential prognostic biomarker in critically patients with AKI and higher FAR was associated with increased risk of in-hospital mortality among these patients.

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